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Search results for m root_codes_WIKIPEDIA in WIKIPEDIA (approximate match)
Status:
Possibly Marketed Outside US
Source:
M005
(2024)
Source URL:
First approved in 2024
Source:
M005
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
M020
(2024)
Source URL:
First approved in 2024
Source:
M020
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
First approved in 2024
Source:
M016
Source URL:
Class (Stereo):
CHEMICAL (MIXED)
Conditions:
Agaricic acid is a resin acid that obtained by extraction with alcohol from obtained from various fungus plants (mushroom) such as Polyporus officinalis (a wood-decay fungus). Since the late 19th century it was used as an antipyretic and antiperspirant, and was official in the German Pharmacopoeia under the name of Agaricinum. Agaricic acid is a sesquihydrate, odorless, almost tasteless, crystalline powder, little soluble in cold water. It is irritant to the gastro-intestinal tract. Experiments on the synthesis of agaricic acid as well as studies of its pharmacological properties are known since 1960s. It was found that Agaricic acid was highly inhibitory (50 to 100%) to malic and alpha-glycerophosphate dehydrogenases of the insect trypanosomatid, Crithidia fasciculata. Agaricic acid is a mycotoxin and is considered under regulations and guidelines established in European Union to protect the consumer from the harmful effects mycotoxins in food. Agaricic acid is among the newest agents to function in
the treatment of wrinkles: it inhibits the cross-linking
process which leads to dermal proteins denaturation.
Status:
Possibly Marketed Outside US
Source:
Teeth Whitening Kit by Nanchang Dental Bright Technology Co.,Ltd.
(2023)
Source URL:
First approved in 2023
Source:
M021
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
21 CFR 347
(2023)
Source URL:
First approved in 2023
Source:
21 CFR 347
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
M016
(2024)
Source URL:
First approved in 2023
Source:
M020
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
M006
(2022)
Source URL:
First approved in 2022
Source:
M006
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
First approved in 2022
Source:
Dr. Zonskin Nunssup Jara by J 1010 Co., Ltd.
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Aceneuramic acid (also known as N-Acetylneuraminic Acid, Neu5Ac, the UX 001 tablets) prolonged released had been filed a marketing authorization application with the European Medicines Agency by Ultragenyx in the EU for the treatment of hereditary inclusion body myopathy (HIBM), a rare, progressive muscle-wasting disease. This compound, a muscle protein stimulant, is also in phase II of the clinical trial for the treatment thrombocytopenia. In addition, recently was made studies, which had shown, that existed the significant positive correlation between serum and salivary sialic acid levels in oral squamous cell carcinoma (OSCC) patients.
Status:
Possibly Marketed Outside US
Source:
NCT01380015: Phase 4 Interventional Completed Osteoarthritis of the Knee
(2011)
Source URL:
First approved in 2021
Source:
M020
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Rosmarinic acid (α-o-caffeoyl-3,4-dihydroxyphenyllactic acid; RA) is a naturally occurring hydroxylated compound commonly found in species of the subfamily Nepetoideae of the Lamiaceae and Boraginaceae, such as Rosmarinus officinalis, Salvia officinalis, and Perilla frutescens. RA is biosynthesized from the amino acids L-phenylalanine and L-tyrosine by eight enzymes that include phenylalanine ammonia lyase and cinnamic acid 4-hydroxylase. Recently, RA and its derivatives have attracted interest for their biological activities, which include anti-inflammatory, anti-oxidant, anti-angiogenic, anti-tumor, and anti-microbial functions. Clinically, RA attenuates T cell receptor-mediated signaling, attenuates allergic diseases like allergic rhinitis and asthma, and 2,4-dinitrofluorobenzene-induced atopic dermatitis-like symptoms, protects from neurotoxicity, and slows the development of Alzheimer's disease. Rosmarinic Acid seems to be able to suppress 5-lipoxygenase and 5-HETE synthesis (a pro-inflammatory compound in the omega-6 metabolic chain). Rosmarinic acid appeared to be effective in suppressing allergies in a dose-dependent manner, with 30% of the placebo group reporting symptom relief compared to 55.6% of the 50mg group and 70% of the 200mg group.
Status:
Possibly Marketed Outside US
Source:
21 CFR 348
(2020)
Source URL:
First approved in 2020
Source:
21 CFR 348
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)