U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C12H22O4
Molecular Weight 230.3007
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DODECANEDIOIC ACID

SMILES

OC(=O)CCCCCCCCCCC(O)=O

InChI

InChIKey=TVIDDXQYHWJXFK-UHFFFAOYSA-N
InChI=1S/C12H22O4/c13-11(14)9-7-5-3-1-2-4-6-8-10-12(15)16/h1-10H2,(H,13,14)(H,15,16)

HIDE SMILES / InChI

Molecular Formula C12H22O4
Molecular Weight 230.3007
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Six weeks' sebacic acid supplementation improves fasting plasma glucose, HbA1c and glucose tolerance in db/db mice.
2010-12
Thiol-functionalized copolymeric polyesters by lipase-catalyzed esterification and transesterification of 1,12-dodecanedioic acid and its diethyl ester, respectively, with 1-thioglycerol.
2010-10
Localized fetomaternal hyperglycemia: spatial and kinetic definition by positron emission tomography.
2010-08-06
Lipase-catalyzed synthesis of poly(amine-co-esters) via copolymerization of diester with amino-substituted diol.
2010-04-12
The effect of processing history on physical behavior and cellular response for tyrosine-derived polyarylates.
2009-12
Poly(glycerol-dodecanoate), a biodegradable polyester for medical devices and tissue engineering scaffolds.
2009-11
Occupational asthma to gel flux containing dodecanedioic acid.
2009-07
Medium-chain fatty acids and glutathione derivatives as inhibitors of S-nitrosoglutathione reduction mediated by alcohol dehydrogenase 3.
2009-06-15
Different oxidized phospholipid molecules unequally affect bilayer packing.
2008-01
Characterization of a methyl jasmonate and wounding-responsive cytochrome P450 of Arabidopsis thaliana catalyzing dicarboxylic fatty acid formation in vitro.
2007-10
Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetic subjects.
2006-11
Copolymeric polythioesters by lipase-catalyzed thioesterification and transthioesterification of alpha,omega-alkanedithiols.
2006-04
Polycondensation of dicarboxylic acids and diols in water catalyzed by surfactant-combined catalysts and successive chain extension.
2006-01
Novel metabolic and molecular findings in hepatic carnitine palmitoyltransferase I deficiency.
2005-11
Approximate linear confidence and curvature of a kinetic model of dodecanedioic acid in humans.
2005-11
Photoinitiated free radical carbonylation enhanced by photosensitizers.
2005-10-13
alpha,omega-Dicarboxylic acid accumulation by acyl-CoA oxidase deficient mutants of Yarrowia lipolytica.
2005-06
Stochastic vs. deterministic uptake of dodecanedioic acid by isolated rat livers.
2005-05
Peroxisomal and mitochondrial oxidation of fatty acids in the heart, assessed from the 13C labeling of malonyl-CoA and the acetyl moiety of citrate.
2005-03-11
Single-crystal 2H NMR of deuterated 1,10-decanedicarboxylic acid included in hydrogenated urea channels.
2004-08
Preparation of dodecanol-tolerant strains of Yarrowia lipolytica.
2004-05
Temporal dynamics and degradation activity of an bacterial inoculum for treating waste metal-working fluid.
2004-03
Effects of fluid composition on mist composition.
2003-11
Macrocyclic musk compounds--an absence of genotoxicity in the Ames test and the in vivo Micronucleus assay.
2002-09-05
Synthesis of D-mannitol and L-iditol derivatives as monomers for the preparation of new regioregular AABB-type polyamides.
2002-04-02
Oxidation of D-[U-(14)C] glucose and [1,12-(14)C] dodecanedioic acid by pancreatic islets from Goto-Kakizaki rats.
2001-08
The metabolic effect of dodecanedioic acid infusion in non-insulin-dependent diabetic patients.
1998-04
Pharmacokinetic analysis of dodecanedioic acid in humans from bolus data.
1995-11-01
Fatty acids and derivatives as antimicrobial agents.
1972-07
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:34:05 GMT 2025
Edited
by admin
on Mon Mar 31 18:34:05 GMT 2025
Record UNII
978YU42Q6I
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NSC-400242
Preferred Name English
DODECANEDIOIC ACID
HSDB   INCI  
INCI  
Official Name English
DECAMETHYLENEDICARBOXYLIC ACID
Systematic Name English
DODECANEDIOIC ACID [HSDB]
Common Name English
1,10-DICARBOXYDECANE
Systematic Name English
1,10-DECANEDICARBOXYLIC ACID
Systematic Name English
N-DODECANE-.ALPHA.,.OMEGA.-DIOIC ACID
Common Name English
Code System Code Type Description
MESH
C036836
Created by admin on Mon Mar 31 18:34:05 GMT 2025 , Edited by admin on Mon Mar 31 18:34:05 GMT 2025
PRIMARY
CAS
693-23-2
Created by admin on Mon Mar 31 18:34:05 GMT 2025 , Edited by admin on Mon Mar 31 18:34:05 GMT 2025
PRIMARY
DAILYMED
978YU42Q6I
Created by admin on Mon Mar 31 18:34:05 GMT 2025 , Edited by admin on Mon Mar 31 18:34:05 GMT 2025
PRIMARY
CHEBI
4676
Created by admin on Mon Mar 31 18:34:05 GMT 2025 , Edited by admin on Mon Mar 31 18:34:05 GMT 2025
PRIMARY
ECHA (EC/EINECS)
211-746-3
Created by admin on Mon Mar 31 18:34:05 GMT 2025 , Edited by admin on Mon Mar 31 18:34:05 GMT 2025
PRIMARY
NSC
400242
Created by admin on Mon Mar 31 18:34:05 GMT 2025 , Edited by admin on Mon Mar 31 18:34:05 GMT 2025
PRIMARY
PUBCHEM
12736
Created by admin on Mon Mar 31 18:34:05 GMT 2025 , Edited by admin on Mon Mar 31 18:34:05 GMT 2025
PRIMARY
WIKIPEDIA
DODECANEDIOIC ACID
Created by admin on Mon Mar 31 18:34:05 GMT 2025 , Edited by admin on Mon Mar 31 18:34:05 GMT 2025
PRIMARY
EPA CompTox
DTXSID3027297
Created by admin on Mon Mar 31 18:34:05 GMT 2025 , Edited by admin on Mon Mar 31 18:34:05 GMT 2025
PRIMARY
HSDB
5745
Created by admin on Mon Mar 31 18:34:05 GMT 2025 , Edited by admin on Mon Mar 31 18:34:05 GMT 2025
PRIMARY
FDA UNII
978YU42Q6I
Created by admin on Mon Mar 31 18:34:05 GMT 2025 , Edited by admin on Mon Mar 31 18:34:05 GMT 2025
PRIMARY