U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C9H9NO4
Molecular Weight 195.1721
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of N-SALICYLOYLGLYCINE

SMILES

OC(=O)CNC(=O)C1=CC=CC=C1O

InChI

InChIKey=ONJSZLXSECQROL-UHFFFAOYSA-N
InChI=1S/C9H9NO4/c11-7-4-2-1-3-6(7)9(14)10-5-8(12)13/h1-4,11H,5H2,(H,10,14)(H,12,13)

HIDE SMILES / InChI

Molecular Formula C9H9NO4
Molecular Weight 195.1721
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Improved colorimetric determination of salicylic acid and its metabolites in urine.
1975 Jul
Simultaneous liquid-chromatographic quantitation of salicylic acid, salicyluric acid, and gentisic acid in urine.
1980 Jan
Improved liquid-chromatography of aspirin, salicylate, and salicyluric acid in plasma, with a modification for determining aspirin metabolites in urine.
1982 May
Disposition of aspirin and its metabolites in the semen of man.
1987 Apr
[Effect of human serum albumin on transport of drugs through human erythrocyte membranes].
1996 Aug
Pharmacokinetics of salicin after oral administration of a standardised willow bark extract.
2001 Aug
Potentiometric and spectroscopic studies on the dimethyltin(IV) complexes of 2-hydroxyhippuric acid.
2001 Jan 15
Does excretion of secondary metabolites always involve a measurable metabolic cost? Fate of plant antifeedant salicin in common brushtail possum, Trichosurus vulpecula.
2001 Jun
Synthesis and evaluation of the analgesic and antiinflammatory activities of O-substituted salicylamides.
2001 Jun
Determination of salicylate, gentisic acid and salicyluric acid in human urine by capillary electrophoresis with laser-induced fluorescence detection.
2001 Mar 5
Identification and determination of salicylic acid and salicyluric acid in urine of people not taking salicylate drugs.
2002 Jan
First- and second-order multivariate calibration applied to biological samples: determination of anti-inflammatories in serum and urine.
2002 Oct
Model complexes with naturally occurring ligands (salicylglycine and imidazol) and the biometals copper and cobalt.
2004 Feb
Comparative pharmacokinetics of acetyl salicylic acid and its metabolites in children suffering from autoimmune diseases.
2004 Jan
Life-history traits of standard and autochthonous cladocerans: II. Acute and chronic effects of acetylsalicylic acid metabolites.
2004 Oct
Increased salicylate concentrations in urine of human volunteers after consumption of cranberry juice.
2005 Apr 20
Effect of cotreatment of aspirin metabolites on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster.
2006
UGT1A6 polymorphism and salicylic acid glucuronidation following aspirin.
2007 Aug
Suppressive effect of post- or pre-treatment of aspirin metabolite on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster.
2007 Feb-Apr
Willow leaves' extracts contain anti-tumor agents effective against three cell types.
2007 Jan 31
[Autopsy case of aspirin intoxication: distribution of salicylic acid and salicyluric acid in body fluid and organs].
2007 Oct
Synthesis of a new seleninic acid anhydride and mechanistic studies into its glutathione peroxidase activity.
2008
Salicylic acid sans aspirin in animals and man: persistence in fasting and biosynthesis from benzoic acid.
2008 Dec 24
Chemometric simultaneous estimation of clopidogrel bisulphate and aspirin from combined dosage form.
2008 Jul-Aug
Spatiotemporal integration of molecular and anatomical data in virtual reality using semantic mapping.
2009
Effect of genetic polymorphisms in UDP-glucuronosyltransferase 1A6 (UGT1A6) on acetylsalicylic acid metabolism in healthy female volunteers.
2009
Serum albumin complexation of acetylsalicylic acid metabolites.
2009 Jun
Drug structure-transport relationships.
2010 Dec
Oral administration of ethanol with aspirin increases the concentration of salicylic acid in plasma and organs, especially the brain, in mice.
2010 Jun 10
Terbium-macrocycle complexes as chemical sensors: detection of an aspirin metabolite in urine using a salicylurate-specific receptor site.
2010 May 17
Quantitative analysis of clopidogrel bisulphate and aspirin by first derivative spectrophotometric method in tablets.
2010 Nov
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:59:17 GMT 2023
Edited
by admin
on Fri Dec 15 15:59:17 GMT 2023
Record UNII
5BR3P7J05U
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
N-SALICYLOYLGLYCINE
Systematic Name English
GLYCINE, N-(2-HYDROXYBENZOYL)-
Systematic Name English
NSC-87566
Code English
2-HYDROXYHIPPURIC ACID
Systematic Name English
O-HYDROXYHIPPURIC ACID
Systematic Name English
SALICYLURATE
Common Name English
SALICYLURIC ACID
Systematic Name English
NSC-524135
Code English
SALICYLOYLGLYCINE
Systematic Name English
Classification Tree Code System Code
LOINC 79478-4
Created by admin on Fri Dec 15 15:59:17 GMT 2023 , Edited by admin on Fri Dec 15 15:59:17 GMT 2023
LOINC 79489-1
Created by admin on Fri Dec 15 15:59:17 GMT 2023 , Edited by admin on Fri Dec 15 15:59:17 GMT 2023
Code System Code Type Description
SMS_ID
100000126022
Created by admin on Fri Dec 15 15:59:17 GMT 2023 , Edited by admin on Fri Dec 15 15:59:17 GMT 2023
PRIMARY
EVMPD
SUB33257
Created by admin on Fri Dec 15 15:59:17 GMT 2023 , Edited by admin on Fri Dec 15 15:59:17 GMT 2023
PRIMARY
CHEBI
9008
Created by admin on Fri Dec 15 15:59:17 GMT 2023 , Edited by admin on Fri Dec 15 15:59:17 GMT 2023
PRIMARY
EPA CompTox
DTXSID70197592
Created by admin on Fri Dec 15 15:59:17 GMT 2023 , Edited by admin on Fri Dec 15 15:59:17 GMT 2023
PRIMARY
WIKIPEDIA
Salicyluric acid
Created by admin on Fri Dec 15 15:59:17 GMT 2023 , Edited by admin on Fri Dec 15 15:59:17 GMT 2023
PRIMARY
NSC
87566
Created by admin on Fri Dec 15 15:59:17 GMT 2023 , Edited by admin on Fri Dec 15 15:59:17 GMT 2023
PRIMARY
PUBCHEM
10253
Created by admin on Fri Dec 15 15:59:17 GMT 2023 , Edited by admin on Fri Dec 15 15:59:17 GMT 2023
PRIMARY
CAS
487-54-7
Created by admin on Fri Dec 15 15:59:17 GMT 2023 , Edited by admin on Fri Dec 15 15:59:17 GMT 2023
PRIMARY
NSC
524135
Created by admin on Fri Dec 15 15:59:17 GMT 2023 , Edited by admin on Fri Dec 15 15:59:17 GMT 2023
PRIMARY
ECHA (EC/EINECS)
207-661-6
Created by admin on Fri Dec 15 15:59:17 GMT 2023 , Edited by admin on Fri Dec 15 15:59:17 GMT 2023
PRIMARY
FDA UNII
5BR3P7J05U
Created by admin on Fri Dec 15 15:59:17 GMT 2023 , Edited by admin on Fri Dec 15 15:59:17 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> METABOLITE INACTIVE
MAJOR
URINE