N-SALICYLOYLGLYCINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H9NO4
Molecular Weight	195.1721
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)CNC(=O)C1=CC=CC=C1O

InChI

InChIKey=ONJSZLXSECQROL-UHFFFAOYSA-N

InChI=1S/C9H9NO4/c11-7-4-2-1-3-6(7)9(14)10-5-8(12)13/h1-4,11H,5H2,(H,10,14)(H,12,13)

HIDE SMILES / InChI

Molecular Formula	C9H9NO4
Molecular Weight	195.1721
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Improved colorimetric determination of salicylic acid and its metabolites in urine.	1975 Jul	1137922
Simultaneous liquid-chromatographic quantitation of salicylic acid, salicyluric acid, and gentisic acid in urine.	1980 Jan	7356541
Improved liquid-chromatography of aspirin, salicylate, and salicyluric acid in plasma, with a modification for determining aspirin metabolites in urine.	1982 May	7074905
Disposition of aspirin and its metabolites in the semen of man.	1987 Apr	3680588
[Effect of human serum albumin on transport of drugs through human erythrocyte membranes].	1996 Aug	8831264
Pharmacokinetics of salicin after oral administration of a standardised willow bark extract.	2001 Aug	11599656
Potentiometric and spectroscopic studies on the dimethyltin(IV) complexes of 2-hydroxyhippuric acid.	2001 Jan 15	11237258
Does excretion of secondary metabolites always involve a measurable metabolic cost? Fate of plant antifeedant salicin in common brushtail possum, Trichosurus vulpecula.	2001 Jun	11504015
Synthesis and evaluation of the analgesic and antiinflammatory activities of O-substituted salicylamides.	2001 Jun	11440072
Determination of salicylate, gentisic acid and salicyluric acid in human urine by capillary electrophoresis with laser-induced fluorescence detection.	2001 Mar 5	11254191
Identification and determination of salicylic acid and salicyluric acid in urine of people not taking salicylate drugs.	2002 Jan	11853189
Uraemic toxins induce proximal tubular injury via organic anion transporter 1-mediated uptake.	2002 Jan	11815391
First- and second-order multivariate calibration applied to biological samples: determination of anti-inflammatories in serum and urine.	2002 Oct	12373394
Urinary excretion of salicyluric and salicylic acids by non-vegetarians, vegetarians, and patients taking low dose aspirin.	2003 Sep	12944546
Model complexes with naturally occurring ligands (salicylglycine and imidazol) and the biometals copper and cobalt.	2004 Feb	14729323
Comparative pharmacokinetics of acetyl salicylic acid and its metabolites in children suffering from autoimmune diseases.	2004 Jan	14716747
Pharmacokinetics and metabolic rates of acetyl salicylic acid and its metabolites in an Otomi ethnic group of Mexico.	2004 May	15133250
Life-history traits of standard and autochthonous cladocerans: II. Acute and chronic effects of acetylsalicylic acid metabolites.	2004 Oct	15352270
Simultaneous determination of gentisic, salicyluric and salicylic acid in human plasma using solid-phase extraction, liquid chromatography and electrospray ionization mass spectrometry.	2004 Oct 5	15315774
Increased salicylate concentrations in urine of human volunteers after consumption of cranberry juice.	2005 Apr 20	15826036
Effect of cotreatment of aspirin metabolites on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster.	2006	16931440
UGT1A6 polymorphism and salicylic acid glucuronidation following aspirin.	2007 Aug	17622933
Suppressive effect of post- or pre-treatment of aspirin metabolite on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster.	2007 Feb-Apr	17275250
Willow leaves' extracts contain anti-tumor agents effective against three cell types.	2007 Jan 31	17264881
[Autopsy case of aspirin intoxication: distribution of salicylic acid and salicyluric acid in body fluid and organs].	2007 Oct	18044220
Synthesis of a new seleninic acid anhydride and mechanistic studies into its glutathione peroxidase activity.	2008	18604859
Salicylic acid sans aspirin in animals and man: persistence in fasting and biosynthesis from benzoic acid.	2008 Dec 24	19053387
Chemometric simultaneous estimation of clopidogrel bisulphate and aspirin from combined dosage form.	2008 Jul-Aug	20046769
Spatiotemporal integration of molecular and anatomical data in virtual reality using semantic mapping.	2009	19421373
Effect of genetic polymorphisms in UDP-glucuronosyltransferase 1A6 (UGT1A6) on acetylsalicylic acid metabolism in healthy female volunteers.	2009	19262071
Serum albumin complexation of acetylsalicylic acid metabolites.	2009 Jun	19689242
Drug structure-transport relationships.	2010 Dec	21107662
Oral administration of ethanol with aspirin increases the concentration of salicylic acid in plasma and organs, especially the brain, in mice.	2010 Jun 10	20303949
Terbium-macrocycle complexes as chemical sensors: detection of an aspirin metabolite in urine using a salicylurate-specific receptor site.	2010 May 17	20405964
Quantitative analysis of clopidogrel bisulphate and aspirin by first derivative spectrophotometric method in tablets.	2010 Nov	21969765

Patents

Substance Class	Chemical Created by `admin` on `Wed Jul 05 23:27:31 UTC 2023` Edited by `admin` on `Wed Jul 05 23:27:31 UTC 2023`
Record UNII	5BR3P7J05U
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

N-SALICYLOYLGLYCINE

Systematic Name

English

GLYCINE, N-(2-HYDROXYBENZOYL)-

Systematic Name

English

NSC-87566

Code

English

2-HYDROXYHIPPURIC ACID

Systematic Name

English

O-HYDROXYHIPPURIC ACID

Systematic Name

English

SALICYLURATE

Common Name

English

SALICYLURIC ACID

Systematic Name

English

NSC-524135

Code

English

SALICYLOYLGLYCINE

Systematic Name

English

Classification Tree Code System Code

LOINC

79478-4