N-SALICYLOYLGLYCINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H9NO4
Molecular Weight	195.1721
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)CNC(=O)C1=CC=CC=C1O

InChI

InChIKey=ONJSZLXSECQROL-UHFFFAOYSA-N

InChI=1S/C9H9NO4/c11-7-4-2-1-3-6(7)9(14)10-5-8(12)13/h1-4,11H,5H2,(H,10,14)(H,12,13)

HIDE SMILES / InChI

Molecular Formula	C9H9NO4
Molecular Weight	195.1721
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Drug structure-transport relationships.	2010-12	21107662
Quantitative analysis of clopidogrel bisulphate and aspirin by first derivative spectrophotometric method in tablets.	2010-11	21969765
Oral administration of ethanol with aspirin increases the concentration of salicylic acid in plasma and organs, especially the brain, in mice.	2010-06-10	20303949
Terbium-macrocycle complexes as chemical sensors: detection of an aspirin metabolite in urine using a salicylurate-specific receptor site.	2010-05-17	20405964
Serum albumin complexation of acetylsalicylic acid metabolites.	2009-06	19689242
Spatiotemporal integration of molecular and anatomical data in virtual reality using semantic mapping.	2009	19421373
Effect of genetic polymorphisms in UDP-glucuronosyltransferase 1A6 (UGT1A6) on acetylsalicylic acid metabolism in healthy female volunteers.	2009	19262071
Salicylic acid sans aspirin in animals and man: persistence in fasting and biosynthesis from benzoic acid.	2008-12-24	19053387
Synthesis of a new seleninic acid anhydride and mechanistic studies into its glutathione peroxidase activity.	2008	18604859
[Autopsy case of aspirin intoxication: distribution of salicylic acid and salicyluric acid in body fluid and organs].	2007-10	18044220
UGT1A6 polymorphism and salicylic acid glucuronidation following aspirin.	2007-08	17622933
Willow leaves' extracts contain anti-tumor agents effective against three cell types.	2007-01-31	17264881
Chemometric simultaneous estimation of clopidogrel bisulphate and aspirin from combined dosage form.	2006-11-07	20046769
Suppressive effect of post- or pre-treatment of aspirin metabolite on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster.	2006-06-12	17275250
Effect of cotreatment of aspirin metabolites on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster.	2006	16931440
Increased salicylate concentrations in urine of human volunteers after consumption of cranberry juice.	2005-04-20	15826036
Simultaneous determination of gentisic, salicyluric and salicylic acid in human plasma using solid-phase extraction, liquid chromatography and electrospray ionization mass spectrometry.	2004-10-05	15315774
Life-history traits of standard and autochthonous cladocerans: II. Acute and chronic effects of acetylsalicylic acid metabolites.	2004-10	15352270
Pharmacokinetics and metabolic rates of acetyl salicylic acid and its metabolites in an Otomi ethnic group of Mexico.	2004-05	15133250
Model complexes with naturally occurring ligands (salicylglycine and imidazol) and the biometals copper and cobalt.	2004-02	14729323
Comparative pharmacokinetics of acetyl salicylic acid and its metabolites in children suffering from autoimmune diseases.	2004-01	14716747
Urinary excretion of salicyluric and salicylic acids by non-vegetarians, vegetarians, and patients taking low dose aspirin.	2003-09	12944546
First- and second-order multivariate calibration applied to biological samples: determination of anti-inflammatories in serum and urine.	2002-10	12373394
Identification and determination of salicylic acid and salicyluric acid in urine of people not taking salicylate drugs.	2002-01	11853189
Uraemic toxins induce proximal tubular injury via organic anion transporter 1-mediated uptake.	2002-01	11815391
Pharmacokinetics of salicin after oral administration of a standardised willow bark extract.	2001-08	11599656
Does excretion of secondary metabolites always involve a measurable metabolic cost? Fate of plant antifeedant salicin in common brushtail possum, Trichosurus vulpecula.	2001-06	11504015
Synthesis and evaluation of the analgesic and antiinflammatory activities of O-substituted salicylamides.	2001-06	11440072
Determination of salicylate, gentisic acid and salicyluric acid in human urine by capillary electrophoresis with laser-induced fluorescence detection.	2001-03-05	11254191
Potentiometric and spectroscopic studies on the dimethyltin(IV) complexes of 2-hydroxyhippuric acid.	2001-01-15	11237258
[Effect of human serum albumin on transport of drugs through human erythrocyte membranes].	1996-08	8831264
Disposition of aspirin and its metabolites in the semen of man.	1987-04	3680588
Improved liquid-chromatography of aspirin, salicylate, and salicyluric acid in plasma, with a modification for determining aspirin metabolites in urine.	1982-05	7074905
Simultaneous liquid-chromatographic quantitation of salicylic acid, salicyluric acid, and gentisic acid in urine.	1980-01	7356541
Improved colorimetric determination of salicylic acid and its metabolites in urine.	1975-07	1137922

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:15:29 GMT 2025` Edited by `admin` on `Mon Mar 31 18:15:29 GMT 2025`
Record UNII	5BR3P7J05U
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

N-SALICYLOYLGLYCINE

Systematic Name

English

NSC-524135

Preferred Name

English

GLYCINE, N-(2-HYDROXYBENZOYL)-

Systematic Name

English

NSC-87566

Code

English

2-HYDROXYHIPPURIC ACID

Systematic Name

English

O-HYDROXYHIPPURIC ACID

Systematic Name

English

SALICYLURATE

Common Name

English

SALICYLURIC ACID

Systematic Name

English

SALICYLOYLGLYCINE

Systematic Name

English

Classification Tree Code System Code

LOINC

79478-4