Tifurac is a benzofuranacetic acid derivative patented by Syntex, Inc. as an analgesic, anti-inflammatory, and antipyretic agent. In preclinical models, Tifurac can exert anti-inflammatory and analgesic activity in rat paw edema assay and mouse writhing assay.

Denaverine is a benzilacid derivative. It is a phenobarbital-type microsomal enzyme inducer. Denaverine has a relaxing effect on the prepartum uterus and provides an increased flexibility of the soft birth canal. In addition, it has a surface anaestetic effect and an anticonvulsive effect as well as a slightly tranquilizing and antipyretic effect. In veterinary medicine denaverine hydrochloride is used to regulate myometrial contractions during parturition. It is a regularly used substance in obstetrics in veterinary medicine in many European countries.

Denipride is a gastrointestinal agent.

Demecycline is a tetracycline antibiotic drug. Tetracyclines have a broad spectrum of anti-microbial activity and act by interfering with bacterial protein synthesis. Demecycline is used to treat a wide range of infections caused by bacteria. Some of these infections are: Severe acne; Infections of the brain and liver caused by the bacteria Leptospira; Infection caused by Brucella bacteria (brucellosis); Infections caused by Rickettsiae micro-organisms transmitted by lice, fleas, ticks and mites; Infections of the sex organs and organs associated with urination (genito-urinary infections) such as an infection called chancroid, non-gonococcal urethritis; Rare infections such as Tularaemia and bubonic plague. The following undesirable effects have been reported for demecycline: loss of appetite, nausea, vomiting, diarrhea, inflammation of the tongue, difficulty in swallowing, intestinal inflammation, and inflammatory lesions, rashes, redness of the skin, pigmentation, sensitivity to light, acute kidney failure and others.

Cyclopregnol (neurosterone) is a synthetic pregnane steroid, developed in the 1950s by the British Drug Houses, Ltd, for the treatment of psychiatric disorders, such as anxiety, depression and obsessive behavior. In a clinical study, cyclopregnol was not superior to placebo and was inferior to chlorpromazine.

Cloxypendyl is an antipsychotic drug, invented in the 1960s by the Deutsche Gold und Silber-Scheideanstalt vormals Roessler. The compound was 3.5 times more effective than chlorpromazine in the mouse catalepsy test. No clinical and commercial development was reported.

Cotriptyline is a tricyclic antidepressant, discovered by French Societe Industrielle pour la Fabrication des Antibiotiques. The compound antagonized reserpine-induced ptosis and bradycardia in rodents and potentiated stereotyped behavior induced by administration of d-amphetamine.

Cloroqualone is an analog of Methaqualone developed in 1980. Cloroqualone possesses a weaker sedative effect than Methaqualone. It was marketed in France and some other European countries either alone or in combination with other ingredients as cough medicine.

Cloxacepride is an amide of the dopamine antagonist metoclopramide. It was discovered in the 1980s by Merkle and Panlabs and was found to possess anti-allergic properties. Cloxacepride demonstrated activity in a rat Passive Cutaneous Anaphylaxis (PCA) model after oral administration. Cloxacepride did not protect against histamine-induced anaphylaxis in guinea pigs, thus it was concluded that the effect of cloxacepride is not mediated by histamine receptors. In experiments with human mast cells from adenoidal tissues, cloxacepride at concentrations 10-100 uM significantly inhibited concanavalin A (con A) induced histamine release. At higher concentrations, cloxacepride caused the release of histamine. These findings indicate that cloxacepride acts through calmodulin antagonism.

Clorindanic acid is a choleretic indanol derivative. Sterling Drug Inc. patented the compound in the 1960s. The compound is claimed to cause an increase in the rate of bile flow when administered to dogs. In rats, clorindanic acid was shown to have mild analgesic activity and hyperthermic effect.