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Details

Stereochemistry ACHIRAL
Molecular Formula C20H21NO
Molecular Weight 291.3868
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of COTRIPTYLINE

SMILES

CN(C)CC(=O)C=C1C2=C(CCC3=C1C=CC=C3)C=CC=C2

InChI

InChIKey=DRNINDKQWDOFMO-UHFFFAOYSA-N
InChI=1S/C20H21NO/c1-21(2)14-17(22)13-20-18-9-5-3-7-15(18)11-12-16-8-4-6-10-19(16)20/h3-10,13H,11-12,14H2,1-2H3

HIDE SMILES / InChI

Description

Cotriptyline is a tricyclic antidepressant, discovered by French Societe Industrielle pour la Fabrication des Antibiotiques. The compound antagonized reserpine-induced ptosis and bradycardia in rodents and potentiated stereotyped behavior induced by administration of d-amphetamine.

Approval Year

Unknown
139594
Name Type Language
COTRIPTYLINE
INN  
INN  
Official Name English
cotriptyline [INN]
Common Name English
1-(DIMETHYLAMINO)-3-(10,11-DIHYDRO-5H-DIBENZO(A,D)CYCLOHEPTEN-5-YLIDENE)-2-PROPANONE
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C265
Created by admin on Fri Dec 15 16:18:12 UTC 2023 , Edited by admin on Fri Dec 15 16:18:12 UTC 2023
Code System Code Type Description
EVMPD
SUB06812MIG
Created by admin on Fri Dec 15 16:18:12 UTC 2023 , Edited by admin on Fri Dec 15 16:18:12 UTC 2023
PRIMARY
SMS_ID
100000084271
Created by admin on Fri Dec 15 16:18:12 UTC 2023 , Edited by admin on Fri Dec 15 16:18:12 UTC 2023
PRIMARY
WIKIPEDIA
Cotriptyline
Created by admin on Fri Dec 15 16:18:12 UTC 2023 , Edited by admin on Fri Dec 15 16:18:12 UTC 2023
PRIMARY
NCI_THESAURUS
C78004
Created by admin on Fri Dec 15 16:18:12 UTC 2023 , Edited by admin on Fri Dec 15 16:18:12 UTC 2023
PRIMARY
EPA CompTox
DTXSID50188221
Created by admin on Fri Dec 15 16:18:12 UTC 2023 , Edited by admin on Fri Dec 15 16:18:12 UTC 2023
PRIMARY
CAS
34662-67-4
Created by admin on Fri Dec 15 16:18:12 UTC 2023 , Edited by admin on Fri Dec 15 16:18:12 UTC 2023
PRIMARY
ChEMBL
CHEMBL2106088
Created by admin on Fri Dec 15 16:18:12 UTC 2023 , Edited by admin on Fri Dec 15 16:18:12 UTC 2023
PRIMARY
PUBCHEM
71935
Created by admin on Fri Dec 15 16:18:12 UTC 2023 , Edited by admin on Fri Dec 15 16:18:12 UTC 2023
PRIMARY
INN
3110
Created by admin on Fri Dec 15 16:18:12 UTC 2023 , Edited by admin on Fri Dec 15 16:18:12 UTC 2023
PRIMARY
FDA UNII
KQJ4QI511C
Created by admin on Fri Dec 15 16:18:12 UTC 2023 , Edited by admin on Fri Dec 15 16:18:12 UTC 2023
PRIMARY
MESH
C000965
Created by admin on Fri Dec 15 16:18:12 UTC 2023 , Edited by admin on Fri Dec 15 16:18:12 UTC 2023
PRIMARY
ACTIVE MOIETY
Structure of COTRIPTYLINE
NIH
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