COTRIPTYLINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H21NO
Molecular Weight	291.3868
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN(C)CC(=O)C=C1C2=C(CCC3=C1C=CC=C3)C=CC=C2

InChI

InChIKey=DRNINDKQWDOFMO-UHFFFAOYSA-N

InChI=1S/C20H21NO/c1-21(2)14-17(22)13-20-18-9-5-3-7-15(18)11-12-16-8-4-6-10-19(16)20/h3-10,13H,11-12,14H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C20H21NO
Molecular Weight	291.3868
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://patents.google.com/patent/GB1205356A/en

Cotriptyline is a tricyclic antidepressant, discovered by French Societe Industrielle pour la Fabrication des Antibiotiques. The compound antagonized reserpine-induced ptosis and bradycardia in rodents and potentiated stereotyped behavior induced by administration of d-amphetamine.

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:18:12 GMT 2023` Edited by `admin` on `Fri Dec 15 16:18:12 GMT 2023`
Record UNII	KQJ4QI511C
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

COTRIPTYLINE

Official Name

English

cotriptyline [INN]

Common Name

English

1-(DIMETHYLAMINO)-3-(10,11-DIHYDRO-5H-DIBENZO(A,D)CYCLOHEPTEN-5-YLIDENE)-2-PROPANONE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265