CYCLOPREGNOL

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H32O2
Molecular Weight	316.4776
Optical Activity	UNSPECIFIED
Defined Stereocenters	9 / 9
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@]12C[C@]13[C@H](O)C[C@@]4([H])[C@]5([H])CC[C@H](C(C)=O)[C@@]5(C)CC[C@]4([H])[C@@]3(C)CC2

InChI

InChIKey=UGIARLNNAPRCPF-HUPPADNKSA-N

InChI=1S/C21H32O2/c1-12(22)15-4-5-16-14-10-18(23)21-11-13(21)6-9-20(21,3)17(14)7-8-19(15,16)2/h13-18,23H,4-11H2,1-3H3/t13-,14-,15+,16-,17-,18+,19+,20+,21+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C21H32O2
Molecular Weight	316.4776
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	9 / 9
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://books.google.ru/books?id=rDUMWpvOgjkC&pg=PA3&redir_esc=y#v=onepage&q&f=false | https://doi.org/10.1192/bjp.114.512.843 | https://doi.org/10.1039/JR9570000665

Cyclopregnol (neurosterone) is a synthetic pregnane steroid, developed in the 1950s by the British Drug Houses, Ltd, for the treatment of psychiatric disorders, such as anxiety, depression and obsessive behavior. In a clinical study, cyclopregnol was not superior to placebo and was inferior to chlorpromazine.

Originator

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:18:13 UTC 2023` Edited by `admin` on `Fri Dec 15 16:18:13 UTC 2023`
Record UNII	Z06494074X
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CYCLOPREGNOL

Official Name

English

6.BETA.-HYDROXY-3,5-CYCLOPREGNAN-20-ONE

Common Name

English

cyclopregnol [INN]

Common Name

English

3,5-CYCLOPREGNAN-20-ONE, 6-HYDROXY-, (3.BETA.,5S,6.BETA.)-

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29756