U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 621 - 630 of 824 results

Status:
Possibly Marketed Outside US
Source:
Kiehls Ultra Light Daily UV Defense Aqua Gel SPF 50 Anti-Pollution by L'Oreal USA Products Inc.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Diethylamino hydroxybenzoyl hexyl benzoate (DHHB) is an organic UV filter with high absorption in the UV-A range that minimizes the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic photodamage. In in vitro studies, DHHB was not shown to be mutagenic, clastogenic, or phototoxic. DHHB was approved in Europe in 2005, is also marketed in the U.S., South America, Mexico, Japan and Taiwan, and is used in concentrations up to 10% in sunscreen products, either alone or in combination with other UV absorbers. Only a minor amount of diethylamino hydroxybenzoyl hexyl benzoate will undergo percutaneous absorption and most will remain in the upper layers of the skin. Fluorescence spectroscopy showed that DHHB and avobenzone (another chemical sunscreen ingredient) interact by a static quenching mechanism and DHHB did not affect the avobenzone excited state lifetime.
Status:
Possibly Marketed Outside US
Source:
Technescan MAG3™ by Tracer Pharma
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Betiatide (CAS 103725-47-9; aka S-benzoylmercapto¬acetyltriglycine or 2-[[2-[[2-[(2-benzoylsulfanylacetyl)¬amino]¬acetyl]¬amino]¬acetyl]¬amino] acetic acid) is the API in TechneScan MAG3™; a kit for the preparation of technetium Tc 99m mertiatide. It is used in the diagnosis of congenital and acquired abnormalities, renal failure, urinary tract obstruction and calculi. Furthermore it is used in providing renal function, split function, renal angiograms and renogram curves for whole kidney and renal cortex. Betiatide is light sensitive and must be protected as such.
Status:
Possibly Marketed Outside US
Source:
Fluoxetine
Source URL:
First approved in 1984
Source:
NU-DERM SUNFADER Skin Lightener with Sunscreen (SPF 15) PABA FREE by OMP, INC.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Parabens are widely used preservatives in basic necessities such as cosmetic and pharmaceutical products. It was found, that butylparaben has estrogenic and antiandrogenic properties and is known to reduce sperm counts in rats following perinatal exposure. In addition was observed, that butylparaben exerted endocrine disrupting effects on both male and female offspring. In 2009-2010, 80 pregnant women from Ottawa Canada participated in the Plastics and Personal-Care Product Use in Pregnancy (P4) Study. Women kept a diary of products that they used 24 h prior to and during the collection. All parabens measured in maternal urine had moderate to high reproducibility. Women who used lotions in the past 24 h had significantly higher geometric mean paraben concentrations (80-110%) in their urine than women who reported no use in the past 24 h. Women who used shampoo, conditioner, and cosmetics also showed 70-80% higher butylparaben concentrations in their urine.

Showing 621 - 630 of 824 results