BETIATIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H17N3O6S
Molecular Weight	367.377
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)CNC(=O)CNC(=O)CNC(=O)CSC(=O)C1=CC=CC=C1

InChI

InChIKey=VDPYMEBVIDZKMD-UHFFFAOYSA-N

InChI=1S/C15H17N3O6S/c19-11(16-6-12(20)18-8-14(22)23)7-17-13(21)9-25-15(24)10-4-2-1-3-5-10/h1-5H,6-9H2,(H,16,19)(H,17,21)(H,18,20)(H,22,23)

HIDE SMILES / InChI

Description
Sources: http://www.tracer-pharma.com/products/

Betiatide (CAS 103725-47-9; aka S-benzoylmercapto¬acetyltriglycine or 2-[[2-[[2-[(2-benzoylsulfanylacetyl)¬amino]¬acetyl]¬amino]¬acetyl]¬amino] acetic acid) is the API in TechneScan MAG3™; a kit for the preparation of technetium Tc 99m mertiatide. It is used in the diagnosis of congenital and acquired abnormalities, renal failure, urinary tract obstruction and calculi. Furthermore it is used in providing renal function, split function, renal angiograms and renogram curves for whole kidney and renal cortex. Betiatide is light sensitive and must be protected as such.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Renal failure 9 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0571c18b-1d5e-47bd-bddf-54d74ce1b442	Diagnostic		Approved 8429	Technescan MAG3™ Approved Use Technetium Tc 99m mertiatide is a renal imaging agent for use in the diagnosis of congenital and acquired abnormalities, renal failure, urinary tract obstruction, and calculi in adults and pediatric patients. (See Pediatric Use.) It is a diagnostic aid in providing renal function, split function, renal angiograms, and renogram curves for whole kidney and renal cortex Launch Date 2008

PubMed

Title	Date	PubMed
[(99m)Tc]MAG(3)-mannosyl-dextran: a receptor-binding radiopharmaceutical for sentinel node detection.	2001 Jul	11516693

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Name

Type

Language

BETIATIDE

Official Name

English

S-BENZOYLMERCAPTOACETYLTRIGLYCINE

Common Name

English

N-[N-[N-(Mercaptoacetyl)glycyl]glycyl]glycine benzoate (ester)

Common Name

English

GLYCINE, N-(N-(N-((BENZOYLTHIO)ACETYL)GLYCYL)GLYCYL)-

Systematic Name

English

THIOBENZOIC ACID, S-ESTER WITH N-(N-(N-(MERCAPTOACETYL)GLYCYL)GLYCYL)GLYCINE

Common Name

English

betiatide [INN]

Common Name

English

BETIATIDE [USAN]

Common Name

English

MP-600

Code

English

Betiatide [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1937