U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C24H31NO4
Molecular Weight 397.5072
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIETHYLAMINO HYDROXYBENZOYL HEXYL BENZOATE

SMILES

CCCCCCOC(=O)C1=CC=CC=C1C(=O)C2=C(O)C=C(C=C2)N(CC)CC

InChI

InChIKey=FDATWRLUYRHCJE-UHFFFAOYSA-N
InChI=1S/C24H31NO4/c1-4-7-8-11-16-29-24(28)20-13-10-9-12-19(20)23(27)21-15-14-18(17-22(21)26)25(5-2)6-3/h9-10,12-15,17,26H,4-8,11,16H2,1-3H3

HIDE SMILES / InChI
Diethylamino hydroxybenzoyl hexyl benzoate (DHHB) is an organic UV filter with high absorption in the UV-A range that minimizes the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic photodamage. In in vitro studies, DHHB was not shown to be mutagenic, clastogenic, or phototoxic. DHHB was approved in Europe in 2005, is also marketed in the U.S., South America, Mexico, Japan and Taiwan, and is used in concentrations up to 10% in sunscreen products, either alone or in combination with other UV absorbers. Only a minor amount of diethylamino hydroxybenzoyl hexyl benzoate will undergo percutaneous absorption and most will remain in the upper layers of the skin. Fluorescence spectroscopy showed that DHHB and avobenzone (another chemical sunscreen ingredient) interact by a static quenching mechanism and DHHB did not affect the avobenzone excited state lifetime.

Approval Year

Name Type Language
DIETHYLAMINO HYDROXYBENZOYL HEXYL BENZOATE
INCI  
INCI  
Official Name English
HEXYL 2-(4-(DIETHYLAMINO)-2-HYDROXYBENZOYL)BENZOATE
Systematic Name English
BENZOIC ACID, 2-(4-(DIETHYLAMINO)-2-HYDROXYBENZOYL)-, HEXYL ESTER
Common Name English
Diethylamino hydroxybenzoyl hexyl benzoate [WHO-DD]
Common Name English
UVINUL A PLUS
Common Name English
DIETHYLAMINO HYDROXYBENZOYL HEXYL BENZOATE [INCI]
Common Name English
DIETHYLAMINO HYDROXYBENZOYL HEXYL BENZOATE [MI]
Common Name English
Code System Code Type Description
FDA UNII
ANQ870JD20
Created by admin on Fri Dec 15 17:12:08 GMT 2023 , Edited by admin on Fri Dec 15 17:12:08 GMT 2023
PRIMARY
CAS
302776-68-7
Created by admin on Fri Dec 15 17:12:08 GMT 2023 , Edited by admin on Fri Dec 15 17:12:08 GMT 2023
PRIMARY
SMS_ID
100000170390
Created by admin on Fri Dec 15 17:12:08 GMT 2023 , Edited by admin on Fri Dec 15 17:12:08 GMT 2023
PRIMARY
DAILYMED
ANQ870JD20
Created by admin on Fri Dec 15 17:12:08 GMT 2023 , Edited by admin on Fri Dec 15 17:12:08 GMT 2023
PRIMARY
EPA CompTox
DTXSID60184370
Created by admin on Fri Dec 15 17:12:08 GMT 2023 , Edited by admin on Fri Dec 15 17:12:08 GMT 2023
PRIMARY
DRUG BANK
DB11269
Created by admin on Fri Dec 15 17:12:08 GMT 2023 , Edited by admin on Fri Dec 15 17:12:08 GMT 2023
PRIMARY
PUBCHEM
10111431
Created by admin on Fri Dec 15 17:12:08 GMT 2023 , Edited by admin on Fri Dec 15 17:12:08 GMT 2023
PRIMARY
WIKIPEDIA
Diethylamino hydroxybenzoyl hexyl benzoate
Created by admin on Fri Dec 15 17:12:08 GMT 2023 , Edited by admin on Fri Dec 15 17:12:08 GMT 2023
PRIMARY
DRUG CENTRAL
4602
Created by admin on Fri Dec 15 17:12:08 GMT 2023 , Edited by admin on Fri Dec 15 17:12:08 GMT 2023
PRIMARY
EVMPD
SUB184267
Created by admin on Fri Dec 15 17:12:08 GMT 2023 , Edited by admin on Fri Dec 15 17:12:08 GMT 2023
PRIMARY
RXCUI
1426392
Created by admin on Fri Dec 15 17:12:08 GMT 2023 , Edited by admin on Fri Dec 15 17:12:08 GMT 2023
PRIMARY RxNorm
MERCK INDEX
m11780
Created by admin on Fri Dec 15 17:12:08 GMT 2023 , Edited by admin on Fri Dec 15 17:12:08 GMT 2023
PRIMARY