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Restrict the search for
quinine
to a specific field?
Status:
US Previously Marketed
Source:
PYTEST by AVENT
(1997)
Source URL:
First approved in 1997
Source:
PYTEST by AVENT
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Urea C-14 is a urea molecule radiolabelled with a radioactive carbon-14. Urea C-14 Breath Test is indicated for use in the detection of gastric urease as an aid in the diagnosis of H.pylori infection in the human stomach. The test utilizes a liquid scintillation counter for the measurement of CO in breath samples. To detect H.pylori, urea labeled with C is swallowed by the patient. If gastric urease from H.pylori is present, urea is split to form CO and NH at the interface between the gastric epithelium and lumen and CO is absorbed into the blood and exhaled in the breath. Antibiotics, proton pump inhibitors, sucralfate, and bismuth preparations are known to suppress H.pylori. Ingestion of antibiotics or bismuth within 4 weeks and proton pump inhibitors or sucralfate within 2 weeks prior to performing the test may give false negative results.
Status:
US Previously Marketed
Source:
Quinine Valerate N.F.
(1921)
Source URL:
First marketed in 1921
Class (Stereo):
CHEMICAL (ABSOLUTE)
Quinine valerate is a salt of anti-malarial alkaloid quinine. Quinine valerate is considered to exert the same anti-malarial activity as the parent compound. Quinine valerate may be mutagenic in E. coli HCR+ strains.
Status:
US Previously Marketed
Source:
Sodium Hypophosphite U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Sodium Hypophosphite U.S.P.
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Hypophosphite is a strong reducing agent, that has been used in the 1850s as a remedy for pulmonary tuberculosis. Hypophosphites were used extensively in pharmaceutical preparations, elixirs, and tonics. Hypophosphite does not appear to have adverse toxicological effects, and the sodium, calcium, and potassium salts are considered GRAS. Hypophosphite use in foods may not be limited to one function. Hypophosphites have been used in foods as antioxidants, stabilizers, meat pickling accelerator, and vegetable protein flow inducer.
Status:
US Previously Marketed
Source:
Quinine Hypophosphite N.F.
(1921)
Source URL:
First marketed in 1921
Source:
Quinine Hypophosphite N.F.
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
QUININE HYPOPHOSPHITE, a salt of quinine, was formerly used, along with the hypophosphites of sodium, potassium, calcium, and iron, in the treatment of phthisis and neurasthenic conditions.
Status:
US Previously Marketed
Source:
Quinine and Urea Hydrochloride U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Quinine and Urea Hydrochloride U.S.P.
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Quinine urea mixture is a long-acting local anesthetic and analgesic. However, the quinine-urea mixture could delay wound healing if directly injected into wound edges. A syringe with a long offset needle such as Moynihan’s for infiltrating “at a Distance from the Incision.” is recommended for quinine urea delivery.
Status:
US Previously Marketed
Source:
Quinine Salicylate U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Quinine Salicylate U.S.P.
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Quinine soluble salts possess an extremely bitter taste, that may have a perplexing problem especially to children. That is why one of the most common combinations for oral administration is a slightly soluble quinine salicylate salt. It is known that now quinine is used in the absence of artemisin combination therapies (ARTs) to treat CQ resistant (CQR) P. falciparum malaria. Although the precise mechanism of the antimalarial activity of quinine is not completely understood, it can act via the inhibition on nucleic acid synthesis, on protein synthesis, and on glycolysis in Plasmodium falciparum, and also drug can affect via the binding with hemazoin in parasitized erythrocytes.
Status:
US Previously Marketed
Source:
Formic Acid N.F.
(1921)
Source URL:
First marketed in 1921
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Formic acid is the simplest carboxylic acid. In nature, formic acid is found in the stings and bites of many insects of the order Hymenoptera, including bees and ants. The principal use of formic acid is as a preservative and antibacterial agent in livestock feed. When sprayed on fresh hay or other silage, it arrests certain decay processes and causes the feed to retain its nutritive value longer. In medicine 85% formic acid application is a safe, economical, and effective alternative in the treatment of common warts with few side-effects and good compliance.
Status:
US Previously Marketed
Source:
21 CFR 310.544(a) smoking deterrent quinine ascorbate
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Quinine ascorbate is a salt of antimalarial drug quinine and ascorbic acid (vitamin C). Ascorbate reduces the potency of quinolone-containing anti-malarial drugs. Quinine ascorbate was marketed as a component of over-the-counter smoking deterrent products but was not recognized as safe by the FDA regulation in 1993.
Status:
Possibly Marketed Outside US
Source:
ANDA070433
(1987)
Source URL:
First approved in 1987
Source:
ANDA070433
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Water O-15 as a diagnostic agent that was used in H215O-positron emission tomography/magnetic resonance imaging for noninvasive measurement of cerebral blood flow.
Status:
Possibly Marketed Outside US
Source:
21 CFR 333A
(2018)
Source URL:
First approved in 1978
Source:
K-PhosNo. 2 by Beach Products, Inc.
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
