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Details

Stereochemistry ACHIRAL
Molecular Formula CH2O2
Molecular Weight 46.0254
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FORMIC ACID

SMILES

OC=O

InChI

InChIKey=BDAGIHXWWSANSR-UHFFFAOYSA-N
InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)

HIDE SMILES / InChI

Description

Formic acid is the simplest carboxylic acid. In nature, formic acid is found in the stings and bites of many insects of the order Hymenoptera, including bees and ants. The principal use of formic acid is as a preservative and antibacterial agent in livestock feed. When sprayed on fresh hay or other silage, it arrests certain decay processes and causes the feed to retain its nutritive value longer. In medicine 85% formic acid application is a safe, economical, and effective alternative in the treatment of common warts with few side-effects and good compliance.

Originator

Approval Year

1921
1467
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8297
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
Approved
8429
EndWarts PEN

Approved Use

EndWarts PEN is a unique and effective wart treatment
PubMed

PubMed

TitleDatePubMed
Phytanic acid is ligand and transcriptional activator of murine liver fatty acid binding protein.
1999 Apr
Specificity of endogenous fatty acid release during tumor necrosis factor-induced apoptosis in WEHI 164 fibrosarcoma cells.
1999 Dec
Impaired expression of the uncoupling protein-3 gene in skeletal muscle during lactation: fibrates and troglitazone reverse lactation-induced downregulation of the uncoupling protein-3 gene.
2000 Jul
Analysis of triacylglycerols with non-aqueous reversed-phase liquid chromatography and positive ion electrospray tandem mass spectrometry.
2001
Brain dystrophin-glycoprotein complex: persistent expression of beta-dystroglycan, impaired oligomerization of Dp71 and up-regulation of utrophins in animal models of muscular dystrophy.
2001
Growth kinetics, diffraction properties and effect of agarose on the stability of a novel crystal form of Thermus thermophilus aspartyl-tRNA synthetase-1.
2001 Apr
Influence of particle size in the effect of polyethylene on human osteoblastic cells.
2001 Apr
A comparison of salts for the crystallization of macromolecules.
2001 Feb
Nonaqueous capillary electrophoresis-mass spectrometry for separation of venlafaxine and its phase I metabolites.
2001 Feb
Synthesis and biological evaluation of 2-(3'-(1H-tetrazol-5-yl) bicyclo[1.1.1]pent-1-yl)glycine (S-TBPG), a novel mGlu1 receptor antagonist.
2001 Feb
Characterization of the product ions from the collision-induced dissociation of argentinated peptides.
2001 Feb
Efferent neural projections of angiotensin receptor (AT1) expressing neurones in the hypothalamic paraventricular nucleus of the rat.
2001 Feb
Fully automated 96-well liquid-liquid extraction for analysis of biological samples by liquid chromatography with tandem mass spectrometry.
2001 Feb 1
Alternative splicing of fibroblast growth factor receptors in human prostate cancer.
2001 Feb 1
Interaction of hydrophobic anions with the rat skeletal muscle chloride channel ClC-1: effects on permeation and gating.
2001 Feb 1
Physiological responses to mixing in large scale bioreactors.
2001 Feb 13
Exchange coupling in carboxylato-bridged dinuclear copper(II) compounds: a density functional study.
2001 Feb 2
Isoprenylcysteine carboxyl methyltransferase deficiency in mice.
2001 Feb 23
Synthesis, crystal structure, spectral studies, and catechol oxidase activity of trigonal bipyramidal Cu(II) complexes derived from a tetradentate diamide bisbenzimidazole ligand.
2001 Feb 26
Laboratory study on the high-temperature capture of HCl gas by dry-injection of calcium-based sorbents.
2001 Feb-Mar
The inositol 5-phosphatase SHIP is expressed as 145 and 135 kDa proteins in blood and bone marrow cells in vivo, whereas carboxyl-truncated forms of SHIP are generated by proteolytic cleavage in vitro.
2001 Jan
Reclassification of Desulfobacterium phenolicum as Desulfobacula phenolica comb. nov. and description of strain SaxT as Desulfotignum balticum gen. nov., sp. nov.
2001 Jan
Antipseudomonal antibiotics.
2001 Jan
Molecular structure and activity toward DNA of baicalein, a flavone constituent of the Asian herbal medicine "Sho-saiko-to".
2001 Jan
Increased sensitivity of melanocytes to oxidative stress and abnormal expression of tyrosinase-related protein in vitiligo.
2001 Jan
An organically modified silicate-based ethanol biosensor.
2001 Jan 1
Bioisosteres of 9-carboxymethyl-4-oxo-imidazo[1,2-a]indeno-[1,2-e]pyrazin-2-carboxylic acid derivatives. Progress towards selective, potent in vivo AMPA antagonists with longer durations of action.
2001 Jan 22
Ring opening is not rate-limiting in the GTP cyclohydrolase I reaction.
2001 Jan 26
Characterization of BphF, a Rieske-type ferredoxin with a low reduction potential.
2001 Jan 9
Specific glycosidase activity isolated from a random phage display antibody library.
2001 Jan-Feb
Isomerism and solution dynamics of (90)Y-labeled DTPA--biomolecule conjugates.
2001 Jan-Feb
Serum crosslaps correlations with serum ICTP and urine DPD in hemodialyzed and peritoneally dialyzed patients.
2001 Mar
Ultrasonic irradiation of dichlorvos: decomposition mechanism.
2001 Mar
Molecular comparison of the dense granule proteins GRA6 and GRA7 of Neospora hughesi and Neospora caninum.
2001 Mar
Crystallization and preliminary X-ray crystallographic analysis of RNase HIII from Bacillus subtilis.
2001 Mar
Three-dimensional structure of human follicle-stimulating hormone.
2001 Mar
Differential recovery of retinal function after mitochondrial inhibition by methanol intoxication.
2001 Mar
SCO-spondin, a glycoprotein of the subcommissural organ/Reissner's fiber complex: evidence of a potent activity on neuronal development in primary cell cultures.
2001 Mar 1
Papillomavirus capsid protein expression in Escherichia coli: purification and assembly of HPV11 and HPV16 L1.
2001 Mar 16
Induction of activator protein-1 through reactive oxygen species by crystalline silica in JB6 cells.
2001 Mar 23
Expression of monocarboxylate transporter MCT1 in normal and neoplastic human CNS tissues.
2001 Mar 26
Quantitation of itraconazole in rat heparinized plasma by liquid chromatography-mass spectrometry.
2001 Mar 5
Patents

Patents

04061746
3
04337208
3
04345072
3
04350685
3
04400492
8
04555502
3
04639460
3
04661591
3
04665076
3
04757081
4
04829067
3
04870095
4
04871751
6
04886910
30
04894475
3
04916235
70
04929269
3
04965270
7
04978793
3
05037841
3
05041679
6
05053422
4
05087627
6
05099067
3
05101076
6
05130318
4
05130319
3
05141945
3
05143912
5
05147875
3
05153198
3
05153352
36
05173493
3
05175288
3
05198208
8
05198439
5
05200406
3
05221676
3
05232929
3
05236917
27
05245039
3
05246931
6
05246937
4
05250688
3
05258387
9
05266570
4
05274097
3
05286752
3
05288748
4
05290785
3
05292747
4
US20120123157
3
US2160064
3
US5206433
3
WO2013030162A1
3

Sample Use Guides

In Vivo Use Guide
Fifty patients received 85% formic acid application using a topical application/needle puncture technique every other day.
Route of Administration: Topical
In Vitro Use Guide
The adapted Aureobasidium pullulans strain could grow under the stress of 0.5 g/L furfural, 3 g/L HMF, 2g/L acetic acid, and 0.5 g/L formic acid, whereas the wild type did not.
Name Type Language
FORMIC ACID
FCC   FHFI   HSDB   INCI   MART.   MI   USP-RS   VANDF   WHO-DD  
INCI  
Official Name English
VARROMED COMPONENT FORMIC ACID
Brand Name English
FORMIC ACID [MART.]
Common Name English
FORMATE
Common Name English
FORMIC ACID [EP MONOGRAPH]
Common Name English
FORMICUM ACIDUM [HPUS]
Common Name English
FORMIC ACID [FHFI]
Common Name English
FORMIC ACID [MI]
Common Name English
FEMA NO. 2487
Code English
FORMIC ACID COMPONENT OF VARROMED
Brand Name English
METHANOIC ACID
Systematic Name English
FORMIC ACID [FCC]
Common Name English
FORMIC ACID [INCI]
Common Name English
Formic acid [WHO-DD]
Common Name English
FORMICUM ACIDUM
HPUS  
Common Name English
FORMIC ACID [EMA EPAR VETERINARY]
Common Name English
FORMIC ACID [VANDF]
Common Name English
FORMIC ACID [HSDB]
Common Name English
FORMIC ACID [USP-RS]
Common Name English
Classification Tree Code System Code
JECFA EVALUATION FORMIC ACID
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
EMA VETERINARY ASSESSMENT REPORTS VARROMED [AUTHORIZED]
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
DSLD 4255 (Number of products:2)
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
WHO-VATC QP53AG01
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
EPA PESTICIDE CODE 214900
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
CFR 21 CFR 186.1316
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
CFR 21 CFR 172.515
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
Code System Code Type Description
DRUG BANK
DB01942
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY
HSDB
1646
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY
CHEBI
15740
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
CONCEPT Industrial Aid
DAILYMED
0YIW783RG1
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY
EVMPD
SUB13916MIG
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY
FDA UNII
0YIW783RG1
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY
JECFA MONOGRAPH
1
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY
EPA CompTox
DTXSID2024115
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY
RS_ITEM_NUM
1283200
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY
SMS_ID
100000078507
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY
NCI_THESAURUS
C83719
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY
PUBCHEM
284
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY
MERCK INDEX
m5539
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY Merck Index
MESH
C030544
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY
CHEBI
30751
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY
WIKIPEDIA
FORMIC ACID
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY
CAS
64-18-6
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY
CHEBI
52343
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY
RXCUI
4537
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY RxNorm
ECHA (EC/EINECS)
200-579-1
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
PRIMARY
RXCUI
1362748
Created by admin on Fri Dec 15 15:06:12 UTC 2023 , Edited by admin on Fri Dec 15 15:06:12 UTC 2023
ALTERNATIVE
ACTIVE MOIETY
Structure of FORMIC ACID
SALT/SOLVATE (PARENT)
Structure of ALUMINUM FORMATE
SALT/SOLVATE (PARENT)
Structure of AMMONIUM FORMATE
SALT/SOLVATE (PARENT)
Structure of POTASSIUM FORMATE
SALT/SOLVATE (PARENT)
Structure of MAGNESIUM FORMATE DIHYDRATE
SALT/SOLVATE (PARENT)
Structure of CALCIUM FORMATE
SALT/SOLVATE (PARENT)
Structure of SODIUM FORMATE
SALT/SOLVATE (PARENT)
Structure of MAGNESIUM FORMATE
SALT/SOLVATE (PARENT)
Structure of BUTETHAMINE FORMATE
SALT/SOLVATE (PARENT)
Structure of QUININE FORMATE
SALT/SOLVATE (PARENT)
Structure of NICKEL FORMATE
SALT/SOLVATE (PARENT)
Structure of FERRIC FORMATE
NIH
NCATS
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ACCESSIBILITY
DISCLAIMER
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