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Details

Stereochemistry ABSOLUTE
Molecular Formula C20H24N2O2.CH4N2O.ClH
Molecular Weight 420.9337
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of QUININE UREA HYDROCHLORIDE

SMILES

C=C[C@@]1([H])CN2CC[C@@]1([H])C[C@@]2([H])[C@@]([H])(c3ccnc4ccc(cc34)OC)O.C(=N)(N)O.Cl

InChI

InChIKey=VSBIHZIPRXLKFY-HZQSTTLBSA-N
InChI=1S/C20H24N2O2.CH4N2O.ClH/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;2-1(3)4;/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H4,2,3,4);1H/t13-,14-,19-,20+;;/m0../s1

HIDE SMILES / InChI

Molecular Formula C20H24N2O2
Molecular Weight 324.4175
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula CH4N2O
Molecular Weight 60.0553
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula ClH
Molecular Weight 36.4609
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Quinine urea mixture is a long-acting local anesthetic and analgesic. However, the quinine-urea mixture could delay wound healing if directly injected into wound edges. A syringe with a long offset needle such as Moynihan’s for infiltrating “at a Distance from the Incision.” is recommended for quinine urea delivery.

Approval Year

PubMed

PubMed

TitleDatePubMed
Quinine Urea Hydrochloride.
1918 Jun
[Local anesthetic effect of quinine-urea].
1961
Substance Class Chemical
Created
by admin
on Sat Jun 26 01:23:35 UTC 2021
Edited
by admin
on Sat Jun 26 01:23:35 UTC 2021
Record UNII
MC4F54ADXA
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
QUININE UREA HYDROCHLORIDE
Common Name English
QUININE AND UREA HYDROCHLORIDE
Common Name English
CINCHONAN-9-OL, 6'-METHOXY-, (8.ALPHA.,9R)-, COMPD. WITH UREA (1:1), DIHYDROCHLORIDE
Common Name English
Classification Tree Code System Code
CFR 21 CFR 310.547
Created by admin on Sat Jun 26 01:23:35 UTC 2021 , Edited by admin on Sat Jun 26 01:23:35 UTC 2021
Code System Code Type Description
PUBCHEM
56841939
Created by admin on Sat Jun 26 01:23:35 UTC 2021 , Edited by admin on Sat Jun 26 01:23:35 UTC 2021
PRIMARY
EVMPD
SUB33573
Created by admin on Sat Jun 26 01:23:35 UTC 2021 , Edited by admin on Sat Jun 26 01:23:35 UTC 2021
PRIMARY
CAS
549-52-0
Created by admin on Sat Jun 26 01:23:35 UTC 2021 , Edited by admin on Sat Jun 26 01:23:35 UTC 2021
PRIMARY
CAS
6168-97-4
Created by admin on Sat Jun 26 01:23:35 UTC 2021 , Edited by admin on Sat Jun 26 01:23:35 UTC 2021
SUPERSEDED
FDA UNII
MC4F54ADXA
Created by admin on Sat Jun 26 01:23:35 UTC 2021 , Edited by admin on Sat Jun 26 01:23:35 UTC 2021
PRIMARY
EPA CompTox
549-52-0
Created by admin on Sat Jun 26 01:23:35 UTC 2021 , Edited by admin on Sat Jun 26 01:23:35 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE