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Search results for "Pharmacologic Substance[C1909]|Agent Affecting Blood or Body Fluid[C78275]|Diuretic" in comments (approximate match)
Class (Stereo):
CHEMICAL (ACHIRAL)
Sulfonamide derivative Disulfamide was developed as diuretic agent.
Class (Stereo):
CHEMICAL (MIXED)
Bemetizide was used as a thiazidediuretic. The information about the nowadays application of this drug is not available.
Class (Stereo):
CHEMICAL (RACEMIC)
Quincarbate is a quinoline derivative patented by N. V. Philips' Gloeilampenfabrieken as diuretic. At 12.5 mg/kg orally in rats Quincarbate increased urine excretion by 130%.
Status:
Investigational
Source:
INN:sulocarbilate [INN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Sulocarbilate (also known as W-1548-1) is a sulfanilamide derivative and carbonic anhydrase inhibitor with diuretic activity. In preclinical models, Sulocarbilate shows similar efficacy and superior safety profile compared to other agents of this type. Clinically, Sulocarbilate shows the maximum effect as a natriuretic agent in an oral daily dose of 2 g.
Class (Stereo):
CHEMICAL (ACHIRAL)
Sulosemide is a sulfamoylorthanilic acid derivative patented by German chemicals then life-sciences company Hoechst A.-G. as salidiuretic agent.
Class (Stereo):
CHEMICAL (ACHIRAL)
Besunide was studied as a diuretic agent.
Class (Stereo):
CHEMICAL (ACHIRAL)
Besulpamide has been developed as a diuretic agent.
Status:
Investigational
Class (Stereo):
CHEMICAL (RACEMIC)
Ozolinone, an active metabolite of diuretic etozoline was studied also as a loop diuretic. Experiments on dogs have shown that ozolinone, induced stereoselective and prostaglandin-dependent renin secretion, which was involved in the regulation of intra-renal hemodynamics. Information about the current use of this drug is not available.
Status:
Investigational
Source:
INN:hydroxindasate [INN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Hydroxindasate is a 5-hydroxytryptamine receptor antagonist.
Status:
Investigational
Source:
INN:hydracarbazine [INN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Hydracarbazine, a diuretic, was used in France under the brand name Normatensyl as an antihypertensive drug.
