Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C11H16N2O3S |
| Molecular Weight | 256.321 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN1C(=O)C(S\C1=C/C(O)=O)N2CCCCC2
InChI
InChIKey=NQFBZYYUAFJYNS-FPLPWBNLSA-N
InChI=1S/C11H16N2O3S/c1-12-8(7-9(14)15)17-11(10(12)16)13-5-3-2-4-6-13/h7,11H,2-6H2,1H3,(H,14,15)/b8-7-
| Molecular Formula | C11H16N2O3S |
| Molecular Weight | 256.321 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 1 |
| Optical Activity | ( + / - ) |
Ozolinone, an active metabolite of diuretic etozoline was studied also as a loop diuretic. Experiments on dogs have shown that ozolinone, induced stereoselective and prostaglandin-dependent renin secretion, which was involved in the regulation of intra-renal hemodynamics. Information about the current use of this drug is not available.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Effects of ozolinone, a diuretic active metabolite of etozoline, on renal function. I. Clearance studies in dogs. | 1978 Oct |
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| Quantitative evaluation of ototoxic side effects of furosemide, piretanide, bumetanide, azosemide and ozolinone in the cat--a new approach to the problem of ototoxicity. | 1985 Nov |
| Substance Class |
Chemical
Created
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admin
on
Edited
Fri Dec 15 15:40:49 GMT 2023
by
admin
on
Fri Dec 15 15:40:49 GMT 2023
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| Record UNII |
55TIT7J81D
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| Record Status |
Validated (UNII)
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NCI_THESAURUS |
C49184
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56784-39-5
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6436036
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Ozolinone
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C018121
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CHEMBL2105356
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260-383-7
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SUB09582MIG
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C66289
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55TIT7J81D
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100000082777
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3984
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DTXSID30866590
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ENANTIOMER -> RACEMATE | |||
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ENANTIOMER -> RACEMATE |
| Related Record | Type | Details | ||
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PARENT -> METABOLITE ACTIVE |
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| Related Record | Type | Details | ||
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ACTIVE MOIETY |
