QUINCARBATE

Details

Stereochemistry	RACEMIC
Molecular Formula	C17H18ClNO6
Molecular Weight	367.781
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOCC1COC2=C(Cl)C3=C(NC=C(C(=O)OCC)C3=O)C=C2O1

InChI

InChIKey=AZOPNLGKZVSIIQ-UHFFFAOYSA-N

InChI=1S/C17H18ClNO6/c1-3-22-7-9-8-24-16-12(25-9)5-11-13(14(16)18)15(20)10(6-19-11)17(21)23-4-2/h5-6,9H,3-4,7-8H2,1-2H3,(H,19,20)

HIDE SMILES / InChI

Molecular Formula	C17H18ClNO6
Molecular Weight	367.781
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/940121 | https://www.ncbi.nlm.nih.gov/pubmed/940121

Quincarbate is a quinoline derivative patented by N. V. Philips' Gloeilampenfabrieken as diuretic. At 12.5 mg/kg orally in rats Quincarbate increased urine excretion by 130%.

Originator

Approval Year

PubMed

Title	Date	PubMed
A new class of diuretics with the 1,4-dioxino(2,3-g)quinolone structure.	1976 Jul	940121

Patents

Sample Use Guides

In Vivo Use Guide

rat: 12.5 mg/kg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:02:27 GMT 2023` Edited by `admin` on `Fri Dec 15 16:02:27 GMT 2023`
Record UNII	U40Q9GE876
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

QUINCARBATE

Official Name

English

1,4-DIOXINO(2,3-G)QUINOLINE-8-CARBOXYLIC ACID, 10-CHLORO-3-(ETHOXYMETHYL)-2,3,6,9-TETRAHYDRO-9-OXO-, ETHYL ESTER

Systematic Name

English

DU-23187

Code

English

NSC-287475

Code

English

ETHYL 10-CHLORO-3-(ETHOXYMETHYL)-2,3,6,9-TETRAHYDRO-9-OXO-P-DIOXINO(2,3-G)QUINOLINE-8-CARBOXYLATE

Common Name

English

quincarbate [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C448