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Details

Stereochemistry RACEMIC
Molecular Formula C17H18ClNO6
Molecular Weight 367.781
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of QUINCARBATE

SMILES

CCOCC1COC2=C(Cl)C3=C(NC=C(C(=O)OCC)C3=O)C=C2O1

InChI

InChIKey=AZOPNLGKZVSIIQ-UHFFFAOYSA-N
InChI=1S/C17H18ClNO6/c1-3-22-7-9-8-24-16-12(25-9)5-11-13(14(16)18)15(20)10(6-19-11)17(21)23-4-2/h5-6,9H,3-4,7-8H2,1-2H3,(H,19,20)

HIDE SMILES / InChI
Quincarbate is a quinoline derivative patented by N. V. Philips' Gloeilampenfabrieken as diuretic. At 12.5 mg/kg orally in rats Quincarbate increased urine excretion by 130%.

Approval Year

PubMed

PubMed

TitleDatePubMed
A new class of diuretics with the 1,4-dioxino(2,3-g)quinolone structure.
1976 Jul
Patents

Patents

Name Type Language
QUINCARBATE
INN  
INN  
Official Name English
1,4-DIOXINO(2,3-G)QUINOLINE-8-CARBOXYLIC ACID, 10-CHLORO-3-(ETHOXYMETHYL)-2,3,6,9-TETRAHYDRO-9-OXO-, ETHYL ESTER
Systematic Name English
DU-23187
Code English
NSC-287475
Code English
ETHYL 10-CHLORO-3-(ETHOXYMETHYL)-2,3,6,9-TETRAHYDRO-9-OXO-P-DIOXINO(2,3-G)QUINOLINE-8-CARBOXYLATE
Common Name English
quincarbate [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C448
Created by admin on Fri Dec 15 16:02:27 GMT 2023 , Edited by admin on Fri Dec 15 16:02:27 GMT 2023
Code System Code Type Description
PUBCHEM
323967
Created by admin on Fri Dec 15 16:02:27 GMT 2023 , Edited by admin on Fri Dec 15 16:02:27 GMT 2023
PRIMARY
EVMPD
SUB10205MIG
Created by admin on Fri Dec 15 16:02:27 GMT 2023 , Edited by admin on Fri Dec 15 16:02:27 GMT 2023
PRIMARY
EPA CompTox
DTXSID201023897
Created by admin on Fri Dec 15 16:02:27 GMT 2023 , Edited by admin on Fri Dec 15 16:02:27 GMT 2023
PRIMARY
FDA UNII
U40Q9GE876
Created by admin on Fri Dec 15 16:02:27 GMT 2023 , Edited by admin on Fri Dec 15 16:02:27 GMT 2023
PRIMARY
CAS
54340-59-9
Created by admin on Fri Dec 15 16:02:27 GMT 2023 , Edited by admin on Fri Dec 15 16:02:27 GMT 2023
PRIMARY
SMS_ID
100000080273
Created by admin on Fri Dec 15 16:02:27 GMT 2023 , Edited by admin on Fri Dec 15 16:02:27 GMT 2023
PRIMARY
INN
3612
Created by admin on Fri Dec 15 16:02:27 GMT 2023 , Edited by admin on Fri Dec 15 16:02:27 GMT 2023
PRIMARY
NCI_THESAURUS
C74410
Created by admin on Fri Dec 15 16:02:27 GMT 2023 , Edited by admin on Fri Dec 15 16:02:27 GMT 2023
PRIMARY
CAS
50352-23-3
Created by admin on Fri Dec 15 16:02:27 GMT 2023 , Edited by admin on Fri Dec 15 16:02:27 GMT 2023
ALTERNATIVE
ChEMBL
CHEMBL2104710
Created by admin on Fri Dec 15 16:02:27 GMT 2023 , Edited by admin on Fri Dec 15 16:02:27 GMT 2023
PRIMARY
NSC
287475
Created by admin on Fri Dec 15 16:02:27 GMT 2023 , Edited by admin on Fri Dec 15 16:02:27 GMT 2023
PRIMARY