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Restrict the search for
m ceftaroline
to a specific field?
Status:
Possibly Marketed Outside US
Source:
21 CFR 333E
(2020)
Source URL:
First approved in 2020
Source:
21 CFR 333E
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
AQUA DE FOLLI HAIR BOOSTER PRO by ROKIT HEALTHCARE Inc.
(2020)
Source URL:
First approved in 2020
Source:
AQUA DE FOLLI HAIR BOOSTER PRO by ROKIT HEALTHCARE Inc.
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Thymidine is a water-soluble pyrimidine deoxynucleoside and potent thymidine kinase substrate. Thymidine is known to be converted to dTTP and utilized for DNA synthesis. It is also known that thymidine is converted by catabolic enzymes to several end products. Excess thymidine results in high levels of dTTP, which exerts a regulatory feedback inhibition in the nucleotide biosynthesis pathways leading to DNA synthesis. This property of thymidine is used when it is given in high doses to patients with solid tumors. Thymidine is being tested in Phase II of clinical trials for the treatment of cancer and 5'-Nucleotidase Syndrome.
Status:
Possibly Marketed Outside US
Source:
21 CFR 333E
(2020)
Source URL:
First approved in 2020
Source:
21 CFR 333E
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
M016
(2019)
Source URL:
First approved in 2019
Source:
M016
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
21 CFR 348
(2018)
Source URL:
First approved in 2018
Source:
21 CFR 348
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Status:
Possibly Marketed Outside US
First approved in 2018
Source:
AZULENE FINISHING OIL INGREDIENTS by Coty US LLC
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Guaiazulene is a blue compound. It is a derivative of azulene, guaiazulene is a bicyclic sesquiterpene that is a constituent of some essential oils, mainly oil of guaiac and chamomile oil. Guaiazulene is an U.S. FDA-approved cosmetic color additive. Guaiazulene is used in the formulation of bath products, cleansing products, depilatories, hair bleaches, hair conditioners, hair dyes and colors, hair straighteners, permanent waves, skin care products and skin fresheners. Guaiazulene has antioxidant, antifungal, antimicrobial, anti-inflammatory, anti-spasmodic, anti-ulcer, antitumoral activities and relaxant properties. Common side effects are: diarrhea, constipation, etc.
Status:
Possibly Marketed Outside US
Source:
21 CFR 333A
(2017)
Source URL:
First approved in 2017
Source:
21 CFR 333A
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Pigment blue 16 is the metal-free phtalocyane, once found an outlet as a green shade blue but its inferior heat stability and its poorer chemical fastness, coupled with a price almost three times that of the copper containing salt, has resulted in a rapid decline in its consumption for all but very special applications. Pigment blue 16 is used especially to produce metallic finishes. Incorporated in acrylate resin system for this purpose, the pigment is more weatherfast than types of Copper Phthalocyanine Blue. Pigment blue 16 is also used for artists’ paints.
Status:
Possibly Marketed Outside US
First approved in 2017
Source:
M020
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Cinnamic acid is a polyphenol found in cinnamon oil and used in commercial flavorings. Recent studies have shown the pharmacological properties of cinnamic acid and its derivatives, including hepatoprotective, anti-oxidant, and anti-diabetic activities. In preclinical studies cinnamic acid demonstrated to be a promising candidate for the treatment ob obesity and diabetes. The mechanism of action of cinnamic acid in obesity is explained by its ability to inhibit lipases and ACE (angiotensin-converting enzyme). However, there are several hypotesis regarding the effect of cinnamic acid in diabetes: cinnamic acid enhances glucose-induced insulin secretion, prevents palmitic acid-induced lipotoxicity, inhibits palmitic acid-induced alteration of lipogenic gene and protein expression (AMPK, SREBP-1c, FAS, ACC), inhibits DPP IV, exhibits an additive effect on the uptake of glucose, stimulates adiponectin secretion, etc.
Status:
Possibly Marketed Outside US
Source:
21 CFR 348
(2017)
Source URL:
First approved in 2017
Source:
21 CFR 348
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Possibly Marketed Outside US
Source:
T-Support Max by TMIG Inc.
(2017)
Source URL:
First approved in 2017
Source:
T-Support Max by TMIG Inc.
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Fenamiphos is an organophosphate insecticide and nematicide used for the control of nematodes and sucking insects (including aphids and thrips) on food and non-food crops, and for the control of nematodes in the turf. Fenamiphos blocks the enzyme acetylcholinesterase in the target pests. Fenamiphos is a highly toxic poison that acts by inhibiting cholinesterase (ChE) enzymes in the blood and central and peripheral nervous systems. Inhibition of plasma cholinesterase activity is the most sensitive toxicological endpoint in acute and short-term studies on experimental animals. Fenamiphos is applied on a variety of plants such as tobacco, turf, bananas, pineapples, citrus, and other fruit vines, some vegetables, and grains. In Brazil, this pesticide has been extensively used in tomato crop at planting and also in melon.
