Details
Stereochemistry | RACEMIC |
Molecular Formula | C13H22NO3PS |
Molecular Weight | 303.357 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCOP(=O)(NC(C)C)OC1=CC(C)=C(SC)C=C1
InChI
InChIKey=ZCJPOPBZHLUFHF-UHFFFAOYSA-N
InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)
Fenamiphos is an organophosphate insecticide and nematicide used for the control of nematodes and sucking insects (including aphids and thrips) on food and non-food crops, and for the control of nematodes in the turf. Fenamiphos blocks the enzyme acetylcholinesterase in the target pests. Fenamiphos is a highly toxic poison that acts by inhibiting cholinesterase (ChE) enzymes in the blood and central and peripheral nervous systems. Inhibition of plasma cholinesterase activity is the most sensitive toxicological endpoint in acute and short-term studies on experimental animals. Fenamiphos is applied on a variety of plants such as tobacco, turf, bananas, pineapples, citrus, and other fruit vines, some vegetables, and grains. In Brazil, this pesticide has been extensively used in tomato crop at planting and also in melon.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL1743122 Sources: https://www.ncbi.nlm.nih.gov/pubmed/29448871 |
2.8 µM [IC50] | ||
Target ID: CHEMBL5685 Sources: https://www.ncbi.nlm.nih.gov/pubmed/29448871 |
27.5 µM [IC50] | ||
Target ID: CHEMBL220 Sources: https://www.ncbi.nlm.nih.gov/pubmed/17382909 |
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Classification Tree | Code System | Code | ||
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EPA PESTICIDE CODE |
100601
Created by
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Code System | Code | Type | Description | ||
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H4NO3L2HBE
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H4NO3L2HBE
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6452
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FENAMIPHOS
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22224-92-6
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195106
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31070
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DTXSID3024102
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C002698
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38680
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C163656
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244-848-1
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1869713
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fenamiphos
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m5261
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admin on Fri Dec 15 17:48:46 GMT 2023 , Edited by admin on Fri Dec 15 17:48:46 GMT 2023
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PRIMARY | Merck Index |
SUBSTANCE RECORD