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Restrict the search for
m nalidixic acid
to a specific field?
Status:
Class (Stereo):
CHEMICAL (ACHIRAL)
Hydroxypethidine, an opioid analgesic is an opioid receptor agonist. Hydroxypethidine is under the control of narcotic drugs according to US Single Convention 1961.
Status:
Investigational
Source:
NCT02265289: Phase 1 Interventional Completed Healthy
(1999)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Lefradafiban, an orally active prodrug of fradafiban, is a novel glycoprotein (IIb/IIIa) inhibitor for the treatment of unstable angina. The pharmacokinetic and pharmacodynamic properties of lefradafiban were assessed in 130 healthy male volunteers who received a single dose of 10, 50, 75, 100, or 150 mg or multiple doses of 25, 50, 60, 75, 90, or 100 mg three times daily for one week. After both single and multiple doses, receptor occupancy and plasma lefradafiban levels correlated with platelet aggregation. Lefradafiban had been in phase II clinical trials by Boehringer Ingelheim for the treatment of thrombosis. However, it has been terminated.
Status:
Investigational
Source:
NCT00914186: Phase 2 Interventional Completed Atopic Dermatitis
(2009)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Fosfosal (2-phosphonoxybenzoic acid) is a O-phosphorylated derivative of salicylic acid used in analgesic and anti-inflammatory therapy. Fosfosal showed analgesic effect in the acetic acid-induced writhing and in the hot plate tests in mice, and showed antiinflammatory effect in the xylene induced mice ears swelling and in acetic acid induced increased vascular permeability tests in mice. Both the effects had no significant differences between fosfosal and aspirin, but the former had less stomach irritation.
Class (Stereo):
CHEMICAL (ACHIRAL)
ISOFEZOLAC is a non-steroid anti-inflammatory drug, prostaglandin synthetase inhibitor. It is indicated for use in various forms of rheumatoid arthritis and osteoarthritis.
Class (Stereo):
CHEMICAL (ACHIRAL)
Acetiamine (syn. thianeurone or diacetamine) is a thiamine derivative which is rarely used in pharmaceuticals. It is lipid-soluble. It has been studied for the treatment of rheumatic diseases.
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Duometacin is indomethacin derivative. It was developed as analgesic and anti-inflammatory agent.
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Brofezil (ICI 54594) is an ibuprofen derivative with anti-inflammatory and analgesic activity.
Status:
Investigational
Class (Stereo):
CHEMICAL (RACEMIC)
Dapabutan an antiseptic bacteriostatic drug, active against Gram-positive bacteria. Dapabutan is a component of a local antiseptic drug Sterlane.
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Danosteine is an alkylthioacetic acid, developed by the French company Joullie International. The compound is claimed to have mucolytic action, demonstrated by inhibition of endobronchial retention of mucus induced by inhalation of SO2 in rats.
