Details
Stereochemistry | RACEMIC |
Molecular Formula | C22H35IO2 |
Molecular Weight | 454.4177 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(CCCCCCCCCCCCC1=CC=C([123I])C=C1)CC(O)=O
InChI
InChIKey=NPCIWINHUDIWAV-NSYCNWAXSA-N
InChI=1S/C22H35IO2/c1-19(18-22(24)25)12-10-8-6-4-2-3-5-7-9-11-13-20-14-16-21(23)17-15-20/h14-17,19H,2-13,18H2,1H3,(H,24,25)/i23-4
Iodofiltic Acid I-123 is a single-photon branching free fatty acid radiopharmaceutical with potential application in single-photon emission computed tomography (SPECT). Assessment of fatty acid metabolism by radionuclide techniques has a potential role for the early detection of myocardial ischaemia and the assessment of the severity of ischaemic heart disease. The Iodofiltic Acid I-123 scan is preferable because it can provide suitable information for risk stratification just after an acute myocardial infarction (AMI) without requiring the patient to exercise; it can also detect previous ischaemic insult even after recovery of myocardial perfusion, the so- called "ischaemic memory".
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/26477356
111MBq
Route of Administration:
Intravenous
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NCI_THESAURUS |
C2124
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CHEMBL2111094
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636427
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RR-122
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DB05683
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DTXSID60924591
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SUB184431
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100000170452
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Iodofiltic Acid I 123
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0J7USQ749M
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8745
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123748-56-1
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C76684
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ACTIVE MOIETY