U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C22H35IO2
Molecular Weight 454.4177
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of IODOFILTIC ACID I-123

SMILES

CC(CCCCCCCCCCCCC1=CC=C([123I])C=C1)CC(O)=O

InChI

InChIKey=NPCIWINHUDIWAV-NSYCNWAXSA-N
InChI=1S/C22H35IO2/c1-19(18-22(24)25)12-10-8-6-4-2-3-5-7-9-11-13-20-14-16-21(23)17-15-20/h14-17,19H,2-13,18H2,1H3,(H,24,25)/i23-4

HIDE SMILES / InChI
Iodofiltic Acid I-123 is a single-photon branching free fatty acid radiopharmaceutical with potential application in single-photon emission computed tomography (SPECT). Assessment of fatty acid metabolism by radionuclide techniques has a potential role for the early detection of myocardial ischaemia and the assessment of the severity of ischaemic heart disease. The Iodofiltic Acid I-123 scan is preferable because it can provide suitable information for risk stratification just after an acute myocardial infarction (AMI) without requiring the patient to exercise; it can also detect previous ischaemic insult even after recovery of myocardial perfusion, the so- called "ischaemic memory".

Approval Year

PubMed

PubMed

TitleDatePubMed
Iodofiltic Acid I 123.
2006
Patents

Patents

Sample Use Guides

111MBq
Route of Administration: Intravenous
Name Type Language
IODOFILTIC ACID I-123
Common Name English
BMIPP I-123
Code English
IODOFILTIC ACID (123I)
INN  
INN  
Official Name English
BENZENEPENTADECANOIC ACID, 4-(IODO-(SUP 123)I)-.BETA.-METHYL-
Common Name English
IODOFILTIC ACID I 123 [USAN]
Common Name English
ZEMIVA
Brand Name English
iodofiltic acid (¹²³I) [INN]
Common Name English
IODOFILTIC ACID I 123
USAN  
USAN  
Official Name English
123I-BMIPP
Common Name English
(3RS)-15-(4-((SUP 123)I)IODOPHENYL)-3-METHYLPENTADECANOIC ACID
Common Name English
BMIP-P I-123
Code English
Classification Tree Code System Code
NCI_THESAURUS C2124
Created by admin on Fri Dec 15 16:26:25 GMT 2023 , Edited by admin on Fri Dec 15 16:26:25 GMT 2023
Code System Code Type Description
ChEMBL
CHEMBL2111094
Created by admin on Fri Dec 15 16:26:25 GMT 2023 , Edited by admin on Fri Dec 15 16:26:25 GMT 2023
PRIMARY
PUBCHEM
636427
Created by admin on Fri Dec 15 16:26:25 GMT 2023 , Edited by admin on Fri Dec 15 16:26:25 GMT 2023
PRIMARY
USAN
RR-122
Created by admin on Fri Dec 15 16:26:25 GMT 2023 , Edited by admin on Fri Dec 15 16:26:25 GMT 2023
PRIMARY
DRUG BANK
DB05683
Created by admin on Fri Dec 15 16:26:25 GMT 2023 , Edited by admin on Fri Dec 15 16:26:25 GMT 2023
PRIMARY
EPA CompTox
DTXSID60924591
Created by admin on Fri Dec 15 16:26:25 GMT 2023 , Edited by admin on Fri Dec 15 16:26:25 GMT 2023
PRIMARY
EVMPD
SUB184431
Created by admin on Fri Dec 15 16:26:25 GMT 2023 , Edited by admin on Fri Dec 15 16:26:25 GMT 2023
PRIMARY
SMS_ID
100000170452
Created by admin on Fri Dec 15 16:26:25 GMT 2023 , Edited by admin on Fri Dec 15 16:26:25 GMT 2023
PRIMARY
LACTMED
Iodofiltic Acid I 123
Created by admin on Fri Dec 15 16:26:25 GMT 2023 , Edited by admin on Fri Dec 15 16:26:25 GMT 2023
PRIMARY
FDA UNII
0J7USQ749M
Created by admin on Fri Dec 15 16:26:25 GMT 2023 , Edited by admin on Fri Dec 15 16:26:25 GMT 2023
PRIMARY
INN
8745
Created by admin on Fri Dec 15 16:26:25 GMT 2023 , Edited by admin on Fri Dec 15 16:26:25 GMT 2023
PRIMARY
CAS
123748-56-1
Created by admin on Fri Dec 15 16:26:25 GMT 2023 , Edited by admin on Fri Dec 15 16:26:25 GMT 2023
PRIMARY
NCI_THESAURUS
C76684
Created by admin on Fri Dec 15 16:26:25 GMT 2023 , Edited by admin on Fri Dec 15 16:26:25 GMT 2023
PRIMARY