BUTAFOSFAN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H18NO2P
Molecular Weight	179.1971
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCNC(C)(C)P(O)=O

InChI

InChIKey=WCXWARPXYQCRPP-UHFFFAOYSA-N

InChI=1S/C7H18NO2P/c1-4-5-6-8-7(2,3)11(9)10/h8,11H,4-6H2,1-3H3,(H,9,10)

HIDE SMILES / InChI

Molecular Formula	C7H18NO2P
Molecular Weight	179.1971
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/27476644 | https://www.ncbi.nlm.nih.gov/pubmed/25916204 | https://www.ncbi.nlm.nih.gov/pubmed/21943742 | https://www.ncbi.nlm.nih.gov/pubmed/17803732

Butafosfan is a phosphororganic supplement that is given, most commonly with cyanocobalamin, to cattle, swine, horses, and poultry for the prevention or treatment of phosphorus deficiencies. Butafosfan also plays a vital role in hepatic carbohydrate metabolism. In addition, butafosfan has been regarded as an antistress agent in combination with vitamin B12. Studies with butafosfan in different animals have shown that it improved general health status by stimulating feed intake, immune system, and digestive function. Butafosfan has been reported for the treatment of metabolic disorders caused by stress or nutrition problems in various species.

Originator

Approval Year

PubMed

Title	Date	PubMed
First report about the mode of action of combined butafosfan and cyanocobalamin on hepatic metabolism in nonketotic early lactating cows.	2011 Oct	21943742
Effects of butafosfan with or without cyanocobalamin on the metabolism of early lactating cows with subclinical ketosis.	2016 Feb	25916204
Pharmacokinetics of butafosfan after intravenous and intramuscular administration in piglets.	2017 Apr	27476644

Patents

Sample Use Guides

In Vivo Use Guide

Cows: 10 ml/100 kg

Route of Administration: Intravenous

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:26:39 GMT 2023` Edited by `admin` on `Fri Dec 15 16:26:39 GMT 2023`
Record UNII	3Q2LQ1149L
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BUTAFOSFAN

Official Name

English

butafosfan [INN]

Common Name

English

BUTAPHOSPHAN

Common Name

English

(1-(BUTYLAMINO)-1-METHYLETHYL)PHOSPHINIC ACID

Systematic Name

English

1-( N-BUTYLAMINO)-1-METHYLETHYL PHOSPHONOUS ACID

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29730