IODOFILTIC ACID I-123

Details

Stereochemistry	RACEMIC
Molecular Formula	C22H35IO2
Molecular Weight	454.4177
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(CCCCCCCCCCCCC1=CC=C([123I])C=C1)CC(O)=O

InChI

InChIKey=NPCIWINHUDIWAV-NSYCNWAXSA-N

InChI=1S/C22H35IO2/c1-19(18-22(24)25)12-10-8-6-4-2-3-5-7-9-11-13-20-14-16-21(23)17-15-20/h14-17,19H,2-13,18H2,1H3,(H,24,25)/i23-4

HIDE SMILES / InChI

Molecular Formula	C22H35IO2
Molecular Weight	454.4177
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/30000773 | https://www.ncbi.nlm.nih.gov/pubmed/19907882 | https://www.ncbi.nlm.nih.gov/pubmed/20633821 | https://www.ncbi.nlm.nih.gov/pubmed/26477356

Iodofiltic Acid I-123 is a single-photon branching free fatty acid radiopharmaceutical with potential application in single-photon emission computed tomography (SPECT). Assessment of fatty acid metabolism by radionuclide techniques has a potential role for the early detection of myocardial ischaemia and the assessment of the severity of ischaemic heart disease. The Iodofiltic Acid I-123 scan is preferable because it can provide suitable information for risk stratification just after an acute myocardial infarction (AMI) without requiring the patient to exercise; it can also detect previous ischaemic insult even after recovery of myocardial perfusion, the so- called "ischaemic memory".

Originator

Approval Year

PubMed

Title	Date	PubMed
Iodofiltic Acid I 123.	2006	30000773

Patents

Sample Use Guides

In Vivo Use Guide

111MBq

Route of Administration: Intravenous

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:26:25 UTC 2023` Edited by `admin` on `Fri Dec 15 16:26:25 UTC 2023`
Record UNII	0J7USQ749M
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

IODOFILTIC ACID I-123

Common Name

English

BMIPP I-123

Code

English

IODOFILTIC ACID (123I)

Official Name

English

BENZENEPENTADECANOIC ACID, 4-(IODO-(SUP 123)I)-.BETA.-METHYL-

Common Name

English

IODOFILTIC ACID I 123 [USAN]

Common Name

English

ZEMIVA

Brand Name

English

iodofiltic acid (¹²³I) [INN]

Common Name

English

IODOFILTIC ACID I 123

Official Name

English

123I-BMIPP

Common Name

English

(3RS)-15-(4-((SUP 123)I)IODOPHENYL)-3-METHYLPENTADECANOIC ACID

Common Name

English

BMIP-P I-123

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C2124