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Search results for venlafaxine in Related Substance Name (approximate match)

Showing 11 - 20 of 29 results

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DESVENLAFAXINE-O-GLUCURONIDE

68PDXVEFMN

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (EPIMERIC)

N,O-DIDESMETHYLVENLAFAXINE-GLUCURONIDE

1H23L3816Q

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (EPIMERIC)

TRIDESMETHYLVENLAFAXINE

L00G2AX0BL

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (RACEMIC)

2-(Cyclohex-1-en-1-yl)-2-(4-methoxyphenyl)-N, N-dimethylethan-1-amine

NX18EMS9OI

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (RACEMIC)

2-CYCLOHEXYL-2-(4-METHOXYPHENYL)-N,N-DIMETHYLETHYLAMINE

2CH6VK3N06

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (RACEMIC)

N-DESMETHYLVENLAFAXINE

19V5EX4E8B

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (RACEMIC)

Targets:

Serotonin transporter

Norepinephrine transporter

N,O-DIDESMETHYLVENLAFAXINE

DYW3W9739Y

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (RACEMIC)

Conditions:

N,O-Didesmethylvenlafaxine is a metabolite of venlafaxine, an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. In humans, venlafaxine is biotransformed for the most part by CYP2D6 and CYP2C19 isoenzymes to its major metabolite O-desmethylvenlafaxine, and in parallel to N-desmethylvenlafaxine and N,O-didesmethylvenlafaxine. It was shown, that CYP2D6 genotype influenced the O-demethylation whereas CYP2C19 influenced the N-demethylation of venlafaxine and its metabolites.

PLASMA PROTEIN FRACTION (HUMAN)

6D53G0FD0Z

Status:

US Approved Rx (2013)

Source:

BLA125416

(2013)

Source URL:

https://www.fda.gov/media/113210/download

First approved in 1958

Source:

BLA101140

Source URL:

https://www.fda.gov/media/113210/download

Class:

MIXTURE

CYTOCHROME P450 2D6

8E4LAA4357

Subunit 1 (497) Similarity Search

Sequence Search

Subunit 1 (497) Similarity Search

Status:

Investigational

Source:

NCT03534063: Not Applicable Interventional Completed Pain, Postoperative

(2018)

Source URL:

https://clinicaltrials.gov/ct2/show/NCT03534063

Class:

PROTEIN

SODIUM-DEPENDENT NORADRENALINE TRANSPORTER

HN86OLH1NW

Subunit 1 (617) Similarity Search

Sequence Search

Subunit 1 (617) Similarity Search

Status:

Other

Class:

PROTEIN

Structure of DESVENLAFAXINE-O-GLUCURONIDE

EPIMERIC

DESVENLAFAXINE-O-GLUCURONIDE

Structure of N,O-DIDESMETHYLVENLAFAXINE-GLUCURONIDE

EPIMERIC

N,O-DIDESMETHYLVENLAFAXINE-GLUCURONIDE

Structure of TRIDESMETHYLVENLAFAXINE

RACEMIC

TRIDESMETHYLVENLAFAXINE

Structure of 2-(Cyclohex-1-en-1-yl)-2-(4-methoxyphenyl)-N, N-dimethylethan-1-amine

RACEMIC

2-(Cyclohex-1-en-1-yl)-2-(4-methoxyphenyl)-N, N-dimethylethan-1-amine

Structure of 2-CYCLOHEXYL-2-(4-METHOXYPHENYL)-N,N-DIMETHYLETHYLAMINE

RACEMIC

2-CYCLOHEXYL-2-(4-METHOXYPHENYL)-N,N-DIMETHYLETHYLAMINE

Structure of N-DESMETHYLVENLAFAXINE

RACEMIC

N-DESMETHYLVENLAFAXINE

Structure of N,O-DIDESMETHYLVENLAFAXINE

RACEMIC

N,O-DIDESMETHYLVENLAFAXINE

6D53G0FD0Z
Not a public record

Mixture

PLASMA PROTEIN FRACTION (HUMAN)

Protein

CYTOCHROME P450 2D6

Protein

SODIUM-DEPENDENT NORADRENALINE TRANSPORTER

Showing 11 - 20 of 29 results

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