U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 13:49:13 GMT 2023
Edited
by admin
on Sat Dec 16 13:49:13 GMT 2023
Protein Type TRANSPORTER
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
HN86OLH1NW
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM-DEPENDENT NORADRENALINE TRANSPORTER
Common Name English
NOREPINEPHRINE TRANSPORTER
Common Name English
NET1
Common Name English
SLC6A5
Common Name English
NET
Common Name English
SOLUTE CARRIER FAMILY 6 MEMBER 2
Common Name English
NAT1
Common Name English
SLC6A2
Common Name English
Code System Code Type Description
WIKIPEDIA
Norepinephrine transporter
Created by admin on Sat Dec 16 13:49:17 GMT 2023 , Edited by admin on Sat Dec 16 13:49:17 GMT 2023
PRIMARY
FDA UNII
HN86OLH1NW
Created by admin on Sat Dec 16 13:49:17 GMT 2023 , Edited by admin on Sat Dec 16 13:49:17 GMT 2023
PRIMARY
UNIPROT
P23975
Created by admin on Sat Dec 16 13:49:17 GMT 2023 , Edited by admin on Sat Dec 16 13:49:17 GMT 2023
PRIMARY
From To
1_176 1_185
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_184
N 1_192
N 1_198
Related Record Type Details
INHIBITOR -> TARGET
INHIBITOR -> TARGET
RADIOLIGAND->TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
RADIOLIGAND->TARGET
RADIOLIGAND->TARGET
Kd
INHIBITOR -> TARGET
BINDING
IC50
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
IC50
INHIBITOR -> TRANSPORTER
INHIBITOR -> TARGET
Ki
RADIOLIGAND->TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
(−)-tramadol inhibits norepinephrine reuptake
INHIBITOR -> TARGET
Ki
SUBSTRATE -> TARGET
INHIBITOR -> TARGET
IN-VITRO
IC50
RADIOLIGAND->TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
RADIOLIGAND->TARGET
INHIBITOR -> TRANSPORTER
RADIOLIGAND->TARGET
INHIBITOR -> TRANSPORTER
INHIBITOR -> TARGET
LIGAND->TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TARGET
BINDING
IC50
INHIBITOR -> TARGET
INHIBITOR -> TRANSPORTER
INHIBITOR -> TARGET
Ki
INHIBITOR -> TRANSPORTER
WEAK INHIBITOR->TARGET
The weak monoaminergic activity of DPIA suggest no major pharmacological contribution when present in street amphetamine
INHIBITOR -> TARGET
INHIBITOR -> TARGET
IC50
RADIOLIGAND->TARGET
Transport affinity almost identical to norepinephrine.
IC50
INHIBITOR -> TARGET
BINDING
IC50
INHIBITOR -> TRANSPORTER
IN-VITRO
RADIOLIGAND->TARGET
INHIBITOR -> TARGET
INHIBITOR -> TRANSPORTER
IN RAT
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TRANSPORTER
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL