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14
Investigational
2
Possibly Marketed Outside US
1
US Approved Rx
1
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Primary Target
Epidermal growth factor receptor
1
Vascular endothelial growth factor receptor 2
1
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Highest Phase
Approved
1
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Approval Year
Unknown
16
2011
1
2013
1
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Condition
Thyroid cancer
1
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Treatment Modality
Primary
1
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CNS Activity
CNS Penetrant
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Originator
AstraZeneca
1
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Substance Class
Protein
14
Chemical
3
Mixture
1
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Code System
FDA UNII
18
UNIPROT
10
CAS
6
EC (ENZYME CLASS)
6
WIKIPEDIA
6
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Protein Type
ENZYME
4
RECEPTOR
1
TRANSPORTER
1
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ATC Level 1
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
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ATC Level 2
ANTINEOPLASTIC AGENTS
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ATC Level 3
OTHER ANTINEOPLASTIC AGENTS
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ATC Level 4
Protein kinase inhibitors
1
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Substance Form
Principal Form
18
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"vandetanib"
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EPHRIN TYPE-A RECEPTOR 8
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S276B35HIP
Subunit
1
(978) Similarity Search
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Subunit
1
(978) Similarity Search
Status:
Other
Class:
PROTEIN
EPHRIN TYPE-A RECEPTOR 3
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13U1W2G8EZ
Subunit
1
(963) Similarity Search
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Subunit
1
(963) Similarity Search
Status:
Other
Class:
PROTEIN
MULTIDRUG RESISTANCE PROTEIN 1
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22ES734693
Subunit
1
(1280) Similarity Search
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Subunit
1
(1280) Similarity Search
Status:
Other
Class:
PROTEIN
FETAL HEPATIC FLAVIN-CONTAINING MONOOXYGENASE 1 (HUMAN)
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IHD25862WV
Subunit
1
(531) Similarity Search
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Subunit
1
(531) Similarity Search
Status:
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Class:
PROTEIN
FETAL HEPATIC FLAVIN-CONTAINING MONOOXYGENASE 3 (HUMAN)
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9971WH3C6O
Subunit
1
(531) Similarity Search
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Subunit
1
(531) Similarity Search
Status:
Other
Class:
PROTEIN
OCT-2
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482M00274D
Subunit
1
(555) Similarity Search
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Subunit
1
(555) Similarity Search
Status:
Other
Class:
PROTEIN
OATP-8
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66DDF797LP
Subunit
1
(702) Similarity Search
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Subunit
1
(702) Similarity Search
Status:
Other
Class:
PROTEIN
CYTOCHROME P450 3A4
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PUO0521HZV
Subunit
1
(502) Similarity Search
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Subunit
1
(502) Similarity Search
Status:
Other
Class:
PROTEIN
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