EPHRIN TYPE-A RECEPTOR 8

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 16:47:59 GMT 2025` Edited by `admin` on `Tue Apr 01 16:47:59 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	S276B35HIP
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

EEK

Preferred Name

English

EPHRIN TYPE-A RECEPTOR 8

Common Name

English

KIAA1459

Common Name

English

EPH- AND ELK-RELATED KINASE

Common Name

English

TYROSINE-PROTEIN KINASE RECEPTOR EEK

Common Name

English

HEK3

Common Name

English

EPH-LIKE KINASE 3

Common Name

English

Code System Code Type Description

WIKIPEDIA

EPHA8

Created by admin on Tue Apr 01 16:47:59 GMT 2025 , Edited by admin on Tue Apr 01 16:47:59 GMT 2025

PRIMARY

EC (ENZYME CLASS)

EC 2.7.10.1

Created by admin on Tue Apr 01 16:47:59 GMT 2025 , Edited by admin on Tue Apr 01 16:47:59 GMT 2025

PRIMARY

UNIPROT

P29322

Created by admin on Tue Apr 01 16:47:59 GMT 2025 , Edited by admin on Tue Apr 01 16:47:59 GMT 2025

PRIMARY

PHAROS

P29322

Created by admin on Tue Apr 01 16:47:59 GMT 2025 , Edited by admin on Tue Apr 01 16:47:59 GMT 2025

PRIMARY

FDA UNII

S276B35HIP

Created by admin on Tue Apr 01 16:47:59 GMT 2025 , Edited by admin on Tue Apr 01 16:47:59 GMT 2025

PRIMARY

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_313
N	1_380
N	1_405

Related Record Type Details


					F41401512X

Nilotinib

INHIBITOR -> TARGET


					RBZ1571X5H

DASATINIB

INHIBITOR -> TARGET


					YO460OQ37K

INHIBITOR -> TARGET


					H88EPA0A3N

INHIBITOR -> TARGET


					75BNB373NL

1-NM-PP1

INHIBITOR -> TARGET


					5018V4AEZ0

BOSUTINIB

INHIBITOR -> TARGET


					8S7CMB69GB

1H-Imidazo[2,1-f]purine-2,4(3H,8H)-dione, 7-(5-hydroxy-2-methylphenyl)-8-(2-methoxyphenyl)-1-methyl-

INHIBITOR -> TARGET


					10K52CIC1Z

INHIBITOR -> TARGET

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_589] [1_812]		TYROSINE		TYROSINE O-PHOSPHATE	2R86C98KDX

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED)	CHEMICAL