U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Tue Apr 01 16:48:27 GMT 2025
Edited
by admin
on Tue Apr 01 16:48:27 GMT 2025
Protein Sub Type
Sequence Type COMPLETE
Record UNII
C1P36E2V4Q
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DEVELOPMENTALLY-REGULATED EPH-RELATED TYROSINE KINASE
Preferred Name English
EPHRIN TYPE-B RECEPTOR 2
Common Name English
EPHT3
Common Name English
TYRO5
Common Name English
ELK-RELATED TYROSINE KINASE
Common Name English
TYROSINE-PROTEIN KINASE RECEPTOR EPH-3
Common Name English
DRT
Common Name English
RENAL CARCINOMA ANTIGEN NY-REN-47
Common Name English
HEK5
Common Name English
TYROSINE-PROTEIN KINASE TYRO5
Common Name English
ERK
Common Name English
EPH TYROSINE KINASE 3
Common Name English
EPH-LIKE KINASE 5
Common Name English
Code System Code Type Description
FDA UNII
C1P36E2V4Q
Created by admin on Tue Apr 01 16:48:27 GMT 2025 , Edited by admin on Tue Apr 01 16:48:27 GMT 2025
PRIMARY
UNIPROT
P29323
Created by admin on Tue Apr 01 16:48:27 GMT 2025 , Edited by admin on Tue Apr 01 16:48:27 GMT 2025
PRIMARY
EC (ENZYME CLASS)
EC 2.7.10.1
Created by admin on Tue Apr 01 16:48:27 GMT 2025 , Edited by admin on Tue Apr 01 16:48:27 GMT 2025
PRIMARY
PHAROS
P29323
Created by admin on Tue Apr 01 16:48:27 GMT 2025 , Edited by admin on Tue Apr 01 16:48:27 GMT 2025
PRIMARY
WIKIPEDIA
EPH RECEPTOR B2
Created by admin on Tue Apr 01 16:48:27 GMT 2025 , Edited by admin on Tue Apr 01 16:48:27 GMT 2025
PRIMARY
From To
1_44 1_166
1_79 1_89
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_247
N 1_318
N 1_410
N 1_464
Related Record Type Details
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Structure of 1H-Imidazo[2,1-f]purine-2,4(3H,8H)-dione, 7-(5-hydroxy-2-methylphenyl)-8-(2-methoxyphenyl)-1-methyl-
INHIBITOR -> TARGET
Structure of Nilotinib
INHIBITOR -> TARGET
Structure of DASATINIB
INHIBITOR -> TARGET
Structure of VANDETANIB
INHIBITOR -> TARGET
Structure of Glaucarubinone
INHIBITOR -> TARGET
Inhibits phosphorylation and activation of ERK.
Structure of DORSOMORPHIN
INHIBITOR -> TARGET
Structure of WHI-P 154
INHIBITOR -> TARGET

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO ACID SUBSTITUTION [1_584] TYROSINE TYROSINE O-PHOSPHATE 2R86C98KDX
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED) CHEMICAL
NIH
NCATS
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