1-NM-PP1

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H21N5
Molecular Weight	331.4142
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)(C)N1N=C(CC2=C3C=CC=CC3=CC=C2)C4=C1N=CN=C4N

InChI

InChIKey=GDQXJQSQYMMKRA-UHFFFAOYSA-N

InChI=1S/C20H21N5/c1-20(2,3)25-19-17(18(21)22-12-23-19)16(24-25)11-14-9-6-8-13-7-4-5-10-15(13)14/h4-10,12H,11H2,1-3H3,(H2,21,22,23)

HIDE SMILES / InChI

Molecular Formula	C20H21N5
Molecular Weight	331.4142
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Cyclin-dependent kinase 7 5 Target ID: CHEMBL3055 Sources: https://www.ncbi.nlm.nih.gov/pubmed/17386261	Inhibitor 8297		50.0 nM [IC50]
c-Jun N-terminal kinase 1 8 Target ID: CHEMBL2276 Sources: https://www.ncbi.nlm.nih.gov/pubmed/17850214	Inhibitor 8297		140.0 nM [IC50]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 19:10:35 GMT 2023` Edited by `admin` on `Sat Dec 16 19:10:35 GMT 2023`
Record UNII	75BNB373NL
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1-NM-PP1

Code

English

MUTANT KINASES INHIBITOR II

Common Name

English

NM-PP1

Code

English

1-(1,1-Dimethylethyl)-3-(1-naphthalenylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Systematic Name

English

1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-(1,1-dimethylethyl)-3-(1-naphthalenylmethyl)-

Systematic Name

English

1-NM-PP 1

Code

English

1-tert-Butyl-3-(naphthalen-1-ylmethyl)pyrazolo[3,4-d]pyrimidin-4-amine

Systematic Name

English

PP 1 ANALOG II

Common Name

English

PP1 ANALOG II

Common Name

English

Code System Code Type Description

FDA UNII

75BNB373NL

Created by admin on Sat Dec 16 19:10:36 GMT 2023 , Edited by admin on Sat Dec 16 19:10:36 GMT 2023

PRIMARY

PUBCHEM

5154691

Created by admin on Sat Dec 16 19:10:36 GMT 2023 , Edited by admin on Sat Dec 16 19:10:36 GMT 2023

PRIMARY

CAS

221244-14-0

Created by admin on Sat Dec 16 19:10:36 GMT 2023 , Edited by admin on Sat Dec 16 19:10:36 GMT 2023

PRIMARY

EPA CompTox

DTXSID30408954

Created by admin on Sat Dec 16 19:10:36 GMT 2023 , Edited by admin on Sat Dec 16 19:10:36 GMT 2023

PRIMARY

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