DORSOMORPHIN

C(CN1CCCCC1)OC2=CC=C(C=C2)C3=CN4N=CC(=C4N=C3)C5=CC=NC=C5

InChIKey=XHBVYDAKJHETMP-UHFFFAOYSA-N

InChI=1S/C24H25N5O/c1-2-12-28(13-3-1)14-15-30-22-6-4-19(5-7-22)21-16-26-24-23(17-27-29(24)18-21)20-8-10-25-11-9-20/h4-11,16-18H,1-3,12-15H2

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Potency
Ephrin type-A receptor 2 6 Target ID: CHEMBL2068 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20932747	Inhibitor 8297	11.0 nM [IC50]
Vascular endothelial growth factor receptor 2 104 Target ID: CHEMBL279 Sources: https://www.ncbi.nlm.nih.gov/pubmed/12443771	Inhibitor 8297	20.0 nM [IC50]
Vascular endothelial growth factor receptor 1 41 Target ID: CHEMBL1868 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20932747	Inhibitor 8297	11.0 nM [IC50]
MAP kinase-interacting serine/threonine-protein kinase MNK1 1 Target ID: CHEMBL4718 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20932747	Inhibitor 8297	11.0 nM [IC50]
Tyrosine-protein kinase LCK 12 Target ID: CHEMBL258 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20932747	Inhibitor 8297	16.0 nM [IC50]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:57:10 GMT 2023` Edited by `admin` on `Sat Dec 16 11:57:10 GMT 2023`
Record UNII	10K52CIC1Z
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

DORSOMORPHIN

Common Name

English

AMPK INHIBITOR, COMPOUND C

Common Name

English

6-(4-(2-(1-PIPERIDINYL)ETHOXY)PHENYL)-3-(4-PYRIDINYL)PYRAZOLO(1,5-A)PYRIMIDINE

Systematic Name

English

PYRAZOLO(1,5-A)PYRIMIDINE, 6-(4-(2-(1-PIPERIDINYL)ETHOXY)PHENYL)-3-(4-PYRIDINYL)-

Systematic Name

English

Code System Code Type Description

CAS

866405-64-3