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Restrict the search for doravirine to a specific field?

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Showing 11 - 17 of 17 results

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BENZONITRILE, 3-CHLORO-5-((1-((2,5-DIHYDRO-5-OXO-1H-1,2,4-TRIAZOL-3-YL)METHYL)-1,2-DIHYDRO-2-OXO-4-(TRIFLUOROMETHYL)-3-PYRIDINYL)OXY)-

3HPG3X2D6A

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

3-CHLORO-5-((1-((4-METHYL-3,5-DIOXO-1,2,4-TRIAZOLIDIN-1-YL)METHYL)-2-OXO-4-(TRIFLUOROMETHYL)-3-PYRIDYL)OXY)BENZONITRILE

68YY6J2MH4

Search for Structure

Status:

Other

Class (Stereo):

CHEMICAL (ACHIRAL)

PLASMA PROTEIN FRACTION (HUMAN)

6D53G0FD0Z

Status:

US Approved Rx (2013)

Source:

BLA125416

(2013)

Source URL:

https://www.fda.gov/media/113210/download

First approved in 1958

Source:

BLA101140

Source URL:

https://www.fda.gov/media/113210/download

Class:

MIXTURE

CYTOCHROME P450 3A4

PUO0521HZV

Subunit 1 (502) Similarity Search

Sequence Search

Subunit 1 (502) Similarity Search

Status:

Other

Class:

PROTEIN

HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 POLYMERASE

A3Z87NSO0U

Status:

Other

Class:

STRUCTURALLY DIVERSE

HUMAN IMMUNODEFICIENCY VIRUS TYPE 1

859A956UY8

Status:

Other

Class:

STRUCTURALLY DIVERSE

TENOFOVIR DISOPROXIL

F4YU4LON7I

Search for Structure

Status:

US Approved Rx (2021)

Source:

ANDA213541

(2021)

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=213541

First approved in 2001

Source:

NDA021356

Source URL:

https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=021356

Class (Stereo):

CHEMICAL (ABSOLUTE)

Targets:

HIV-1, subtype A 92RW009

HBV replication

Glutamate carboxypeptidase II

Human immunodeficiency virus type 1 reverse transcriptase

Conditions:

HIV-1 infection

HIV-1 infection

(R)-9-(2-Phosphonylmethoxypropyl)adenine (PMPA known as tenofovir) is an antiviral drug. Diphosphate of PMPA acts as a selective inhibitor of the HIV-1 reverse transcriptase. Tenofovir disoproxil was approved for clinical use for the treatment of HIV infection (AIDS) and chronic HBV infection.

Structure of BENZONITRILE, 3-CHLORO-5-((1-((2,5-DIHYDRO-5-OXO-1H-1,2,4-TRIAZOL-3-YL)METHYL)-1,2-DIHYDRO-2-OXO-4-(TRIFLUOROMETHYL)-3-PYRIDINYL)OXY)-

ACHIRAL

BENZONITRILE, 3-CHLORO-5-((1-((2,5-DIHYDRO-5-OXO-1H-1,2,4-TRIAZOL-3-YL)METHYL)-1,2-DIHYDRO-2-OXO-4-(TRIFLUOROMETHYL)-3-PYRIDINYL)OXY)-

Structure of 3-CHLORO-5-((1-((4-METHYL-3,5-DIOXO-1,2,4-TRIAZOLIDIN-1-YL)METHYL)-2-OXO-4-(TRIFLUOROMETHYL)-3-PYRIDYL)OXY)BENZONITRILE

ACHIRAL

3-CHLORO-5-((1-((4-METHYL-3,5-DIOXO-1,2,4-TRIAZOLIDIN-1-YL)METHYL)-2-OXO-4-(TRIFLUOROMETHYL)-3-PYRIDYL)OXY)BENZONITRILE

6D53G0FD0Z
Not a public record

Mixture

PLASMA PROTEIN FRACTION (HUMAN)

Protein

CYTOCHROME P450 3A4

Structurally Diverse

HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 POLYMERASE

Structurally Diverse

HUMAN IMMUNODEFICIENCY VIRUS TYPE 1

Structure of TENOFOVIR DISOPROXIL

ABSOLUTE

TENOFOVIR DISOPROXIL

Showing 11 - 17 of 17 results

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