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National Institutes of Health
NCATS
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Development Status
Investigational
144
US Approved Rx
37
Possibly Marketed Outside US
1
US Previously Marketed
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Primary Target
Receptor tyrosine-protein kinase erbB-2
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Approval Year
Unknown
145
2015
5
2014
4
2024
4
2004
3
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Condition
Breast cancer
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Primary
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Originator
Genentech
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Substance Class
Protein
148
Concept
26
Structurally Diverse
5
Nucleic Acid
4
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Code System
FDA UNII
183
NCI_THESAURUS
183
SMS_ID
169
CAS
159
INN
152
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Protein Type
MONOCLONAL ANTIBODY
126
MONOCLONAL ANTIBODY CONJUGATE
12
BISPECIFIC ANTIBODY
7
BISPECIFIC MONOCLONAL FRAGMENTS
1
MONOCLONAL ANTIBODY FUSION PROTEIN
1
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ATC Level 1
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
25
MUSCULO-SKELETAL SYSTEM
1
NERVOUS SYSTEM
1
VARIOUS
1
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ATC Level 2
ANTINEOPLASTIC AGENTS
22
IMMUNOSUPPRESSANTS
4
DRUGS FOR TREATMENT OF BONE DISEASES
1
OTHER NERVOUS SYSTEM DRUGS
1
THERAPEUTIC RADIOPHARMACEUTICALS
1
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ATC Level 3
OTHER ANTINEOPLASTIC AGENTS
22
IMMUNOSUPPRESSANTS
4
DRUGS AFFECTING BONE STRUCTURE AND MINERALIZATION
1
OTHER NERVOUS SYSTEM DRUGS
1
OTHER THERAPEUTIC RADIOPHARMACEUTICALS
1
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ATC Level 4
Monoclonal antibodies
21
Interleukin inhibitors
2
Selective immunosuppressants
2
Iodine (<sup>131</sup>I) compounds
1
Other antineoplastic agents
1
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Substance Form
Principal Form
182
Salts, Hydrates, Esters, etc.
1
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Search results for
"Pharmacologic Substance[C1909]|Biological Agent[C307]|Antineoplastic Biological Agent"
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CEMIPLIMAB
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6QVL057INT
Subunit
1
(444) Similarity Search
Subunit
2
(444) Similarity Search
Subunit
3
(214) Similarity Search
Subunit
4
(214) Similarity Search
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Subunit
1
(444) Similarity Search
Subunit
2
(444) Similarity Search
Subunit
3
(214) Similarity Search
Subunit
4
(214) Similarity Search
Status:
US Approved Rx (2018)
First approved in 2018
Class:
PROTEIN
GUSELKUMAB
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089658A12D
Subunit
1
(446) Similarity Search
Subunit
2
(446) Similarity Search
Subunit
3
(217) Similarity Search
Subunit
4
(217) Similarity Search
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Subunit
1
(446) Similarity Search
Subunit
2
(446) Similarity Search
Subunit
3
(217) Similarity Search
Subunit
4
(217) Similarity Search
Status:
US Approved Rx (2017)
First approved in 2017
Class:
PROTEIN
INOTUZUMAB OZOGAMICIN
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P93RUU11P7
Subunit
1
(446) Similarity Search
Subunit
2
(446) Similarity Search
Subunit
3
(219) Similarity Search
Subunit
4
(219) Similarity Search
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Subunit
1
(446) Similarity Search
Subunit
2
(446) Similarity Search
Subunit
3
(219) Similarity Search
Subunit
4
(219) Similarity Search
Status:
US Approved Rx (2017)
First approved in 2017
Class:
PROTEIN
OLARATUMAB
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TT6HN20MVF
Subunit
1
(457) Similarity Search
Subunit
2
(457) Similarity Search
Subunit
3
(214) Similarity Search
Subunit
4
(214) Similarity Search
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Subunit
1
(457) Similarity Search
Subunit
2
(457) Similarity Search
Subunit
3
(214) Similarity Search
Subunit
4
(214) Similarity Search
Status:
US Approved Rx (2016)
First approved in 2016
Class:
PROTEIN
DINUTUXIMAB
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7SQY4ZUD30
Subunit
1
(443) Similarity Search
Subunit
2
(443) Similarity Search
Subunit
3
(220) Similarity Search
Subunit
4
(220) Similarity Search
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Subunit
1
(443) Similarity Search
Subunit
2
(443) Similarity Search
Subunit
3
(220) Similarity Search
Subunit
4
(220) Similarity Search
Status:
US Approved Rx (2015)
First approved in 2015
Class:
PROTEIN
ELOTUZUMAB
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1351PE5UGS
Subunit
1
(449) Similarity Search
Subunit
2
(449) Similarity Search
Subunit
3
(214) Similarity Search
Subunit
4
(214) Similarity Search
Export Data
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Subunit
1
(449) Similarity Search
Subunit
2
(449) Similarity Search
Subunit
3
(214) Similarity Search
Subunit
4
(214) Similarity Search
Status:
US Approved Rx (2015)
First approved in 2015
Class:
PROTEIN
DARATUMUMAB
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4Z63YK6E0E
Subunit
1
(452) Similarity Search
Subunit
2
(452) Similarity Search
Subunit
3
(214) Similarity Search
Subunit
4
(214) Similarity Search
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Subunit
1
(452) Similarity Search
Subunit
2
(452) Similarity Search
Subunit
3
(214) Similarity Search
Subunit
4
(214) Similarity Search
Status:
US Approved Rx (2020)
First approved in 2015
Class:
PROTEIN
NECITUMUMAB
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2BT4C47RUI
Subunit
1
(451) Similarity Search
Subunit
2
(451) Similarity Search
Subunit
3
(214) Similarity Search
Subunit
4
(214) Similarity Search
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Subunit
1
(451) Similarity Search
Subunit
2
(451) Similarity Search
Subunit
3
(214) Similarity Search
Subunit
4
(214) Similarity Search
Status:
US Approved Rx (2015)
First approved in 2015
Class:
PROTEIN
NIVOLUMAB
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31YO63LBSN
Subunit
1
(440) Similarity Search
Subunit
2
(440) Similarity Search
Subunit
3
(214) Similarity Search
Subunit
4
(214) Similarity Search
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Subunit
1
(440) Similarity Search
Subunit
2
(440) Similarity Search
Subunit
3
(214) Similarity Search
Subunit
4
(214) Similarity Search
Status:
US Approved Rx (2014)
First approved in 2014
Class:
PROTEIN
BLINATUMOMAB
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4FR53SIF3A
Subunit
1
(504) Similarity Search
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Subunit
1
(504) Similarity Search
Status:
US Approved Rx (2014)
First approved in 2014
Class:
PROTEIN
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