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ELOTUZUMAB
1351PE5UGS
US Approved Rx (2015)
First approved in 2015
General
Record Details
Names
14
Classification
7
Identifiers
16
Subunits
4
Disulfide Links
16
Relationships
1
Active Moiety
1
Characteristic Attributes
2
ELOTUZUMAB
1351PE5UGS
US Approved Rx (2015)
First approved in 2015
General
Approval Year
2015
471
Record Details
Substance Class
Protein
Protein Type
MONOCLONAL ANTIBODY
Protein Sub Type
IGG1
Sequence Origin
HUMANIZED MOUSE
Sequence Type
COMPLETE
Record UNII
1351PE5UGS
Record Status
Validated (UNII)
Record Version
31
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Names
14
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entries
Name
Type
Language
Name
Type
Language
ELOTUZUMAB
Official Name
English
Elotuzumab [WHO-DD]
Common Name
English
HULUC63
Code
English
elotuzumab [INN]
Common Name
English
PDL063
Code
English
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Classification
7
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Classification Tree
Code System
Code
Classification Tree
Code System
Code
Withdrawn
EU ORPHAN DRUG
Withdrawn
Treatment of multiple myeloma
EU-Orphan Drug
EU/3/12/1037
Biological Agent
Pharmacologic Substance
[C1909]
Biological Agent
[C307]
Monoclonal Antibody
NCI_THESAURUS
C20401
Established Pharmacologic Class
Established Pharmacologic Class
[EPC]
SLAMF7-directed Immunostimulatory Antibody
[EPC]
NDF-RT
N0000192338
NEOPLASMS, PLASMA CELL
EMA EPAR
DISEASES
CANCER
NEOPLASMS BY HISTOLOGIC TYPE
NEOPLASMS, PLASMA CELL
MULTIPLE MYELOMA
EMA ASSESSMENT REPORTS
EMPLICITI (AUTHORIZED: MULTIPLE MYELOMA)
Designated/Approved
ORPHAN DRUG
Designated/Approved
Treatment of multiple myeloma
FDA ORPHAN DRUG
348411
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Identifiers
16
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entries
Code System
Code
Type
Description
Code System
Code
Type
Description
NDF-RT
N0000192337
PRIMARY
SLAMF7-directed Antibody Interactions [MoA]
SMS_ID
100000144872
PRIMARY
INN
9074
PRIMARY
DRUG CENTRAL
5072
PRIMARY
FDA UNII
1351PE5UGS
PRIMARY
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Subunits
4
Disulfide Links
16
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entries
From
To
From
To
1_22
1_96
1_146
1_202
1_222
3_214
1_228
2_228
1_231
2_231
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Relationships
1
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Related Record
Type
Details
Related Record
Type
Details
0KAU401ANQ
SLAM FAMILY MEMBER 7
TARGET -> AGONIST
Amount:
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Active Moiety
1
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Related Record
Type
Details
Related Record
Type
Details
1351PE5UGS
ELOTUZUMAB
ACTIVE MOIETY
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Characteristic Attributes
2
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entries
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
MOL_WEIGHT:SEQUENCE
CHEMICAL
SEQUENCE 145420.5 Da (average)
Molecular Formula
CHEMICAL
ESTIMATED
C6476H9962N1714O2016S42
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