GUSELKUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 21:31:11 GMT 2025` Edited by `admin` on `Mon Mar 31 21:31:11 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	089658A12D
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

GUSELKUMAB

Official Name

English

guselkumab [INN]

Preferred Name

English

CNTO-1959

Code

English

GUSELKUMAB [MI]

Common Name

English

CNTO 1959

Code

English

TREMFYA

Brand Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN INTERLEUKIN 23) (HUMAN CNTO 1959 HEAVY CHAIN), DISULFIDE WITH HUMAN CNTO 1959 .LAMBDA.-CHAIN, DIMER

Common Name

English

GUSELKUMAB [PURPLE BOOK CDER]

Common Name

English

GUSELKUMAB [JAN]

Common Name

English

GUSELKUMAB [USAN]

Common Name

English

Guselkumab [WHO-DD]

Common Name

English

Classification Tree Code System Code

WHO-ATC

L04AC16

Created by admin on Mon Mar 31 21:31:12 GMT 2025 , Edited by admin on Mon Mar 31 21:31:12 GMT 2025

NDF-RT

N0000192799

Created by admin on Mon Mar 31 21:31:12 GMT 2025 , Edited by admin on Mon Mar 31 21:31:12 GMT 2025

NCI_THESAURUS

C129822

Created by admin on Mon Mar 31 21:31:12 GMT 2025 , Edited by admin on Mon Mar 31 21:31:12 GMT 2025

NCI_THESAURUS

C20401

Created by admin on Mon Mar 31 21:31:12 GMT 2025 , Edited by admin on Mon Mar 31 21:31:12 GMT 2025

Code System Code Type Description

USAN

ZZ-118

Created by admin on Mon Mar 31 21:31:12 GMT 2025 , Edited by admin on Mon Mar 31 21:31:12 GMT 2025

PRIMARY

RXCUI

1928588

Created by admin on Mon Mar 31 21:31:12 GMT 2025 , Edited by admin on Mon Mar 31 21:31:12 GMT 2025

PRIMARY

NCI_THESAURUS

C150390

Created by admin on Mon Mar 31 21:31:12 GMT 2025 , Edited by admin on Mon Mar 31 21:31:12 GMT 2025

PRIMARY

DAILYMED

089658A12D

Created by admin on Mon Mar 31 21:31:12 GMT 2025 , Edited by admin on Mon Mar 31 21:31:12 GMT 2025

PRIMARY

DRUG CENTRAL

5246

Created by admin on Mon Mar 31 21:31:12 GMT 2025 , Edited by admin on Mon Mar 31 21:31:12 GMT 2025

PRIMARY

SMS_ID

100000165895

Created by admin on Mon Mar 31 21:31:12 GMT 2025 , Edited by admin on Mon Mar 31 21:31:12 GMT 2025

PRIMARY

ChEMBL

CHEMBL2364648

Created by admin on Mon Mar 31 21:31:12 GMT 2025 , Edited by admin on Mon Mar 31 21:31:12 GMT 2025

PRIMARY

DRUG BANK

DB11834

Created by admin on Mon Mar 31 21:31:12 GMT 2025 , Edited by admin on Mon Mar 31 21:31:12 GMT 2025

PRIMARY

FDA UNII

089658A12D

Created by admin on Mon Mar 31 21:31:12 GMT 2025 , Edited by admin on Mon Mar 31 21:31:12 GMT 2025

PRIMARY

LACTMED

Guselkumab

Created by admin on Mon Mar 31 21:31:12 GMT 2025 , Edited by admin on Mon Mar 31 21:31:12 GMT 2025

PRIMARY

EVMPD

SUB179789

Created by admin on Mon Mar 31 21:31:12 GMT 2025 , Edited by admin on Mon Mar 31 21:31:12 GMT 2025

PRIMARY

MERCK INDEX

m12024

Created by admin on Mon Mar 31 21:31:12 GMT 2025 , Edited by admin on Mon Mar 31 21:31:12 GMT 2025

PRIMARY

WIKIPEDIA

Guselkumab

Created by admin on Mon Mar 31 21:31:12 GMT 2025 , Edited by admin on Mon Mar 31 21:31:12 GMT 2025

PRIMARY

INN

9774

Created by admin on Mon Mar 31 21:31:12 GMT 2025 , Edited by admin on Mon Mar 31 21:31:12 GMT 2025

PRIMARY

CAS

1350289-85-8

Created by admin on Mon Mar 31 21:31:12 GMT 2025 , Edited by admin on Mon Mar 31 21:31:12 GMT 2025

PRIMARY

From	To
1_22	1_96
3_22	3_90
2_22	2_96
4_22	4_90
3_139	3_198
4_139	4_198
1_144	1_200
2_144	2_200
1_220	3_216
2_220	4_216
1_226	2_226
1_229	2_229
1_261	1_321
2_261	2_321
1_367	1_425
2_367	2_425

Glycosylation Link Type	Site
N	1_297
N	2_297

Related Record Type Details


					5OL0CTF85B

INTERLEUKIN-23 SUBUNIT ALPHA

TARGET -> INHIBITOR

Amount:

Related Record Type Details

089658A12D

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
amino acid substitution	[1_1] [2_1]		Gln		PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Biological Half-life	PHARMACOKINETIC

Volume of Distribution	PHARMACOKINETIC