U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 1961 - 1970 of 2850 results

Status:
US Previously Marketed
Source:
DARTAL 100MG by SEARLE
(1961)
Source URL:
First approved in 1957
Source:
Dartal by Searle
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


THIOPROPAZATE, a phenothiazine derivative, is a typical antipsychotic. It is a prodrug to perphenazine.
Status:
US Previously Marketed
Source:
PACATAL 25MG by WC
(1961)
Source URL:
First approved in 1957
Source:
Pacatal by Warner/Chilcott
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

PECAZINE is a phenothiazine derivative that was used as an antipsychotic. It is also an allosteric inhibitor of MALT1 paracaspase activity.
Status:
US Previously Marketed
Source:
Tromexan by Geigy
(1950)
Source URL:
First approved in 1950
Source:
Tromexan by Geigy
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Ethyl biscoumacetate is a courmarin that is used as an anticoagulant. It has actions similar to those of Warfarin. It has been used in the management of thromboembolic disorders.
Glutamic acid is a non-essential aminoacid used in biosynthesis of proteins. Besides being a building block of proteins, glutamic acid plays a principal role in neural activation. Glutamate is also responsible for the umami (savory) flavor of certain foods. In medicine, glutamate is used as a metabolic supplemnet in patients undergoing coronary surgery.
Status:
US Previously Marketed
Source:
SPARTASE POTASSIUM ASPARTATE by WYETH
(1961)
Source URL:
First marketed in 1921
Source:
potassium aspartate
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



Disodium aspartate is used in organic biosynthesis.
Status:
US Previously Marketed
Source:
Aconitine U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Aconitine U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



Aconitine is an alkaloid found in the Aconitum species. Aconitine is a highly toxic cardiotoxin and neurotoxin. In China and other countries, the herbal extract containing aconitine was used for the treatment of pain in musculoskeletal disorders, however the safety margin between therapeutic analgesic effect of aconitine and its known cardiotoxic effect is so narrow that the treatment may cause poisoning and death. The mechanism of aconitine action is explained by its ability to activate voltage-dependent sodium-ion channels.
Status:
US Previously Marketed
Source:
DL-alpha tocopheryl acetate
(1921)
Source URL:
First marketed in 1921
Source:
DL-alpha tocopheryl acetate
Source URL:

Class (Stereo):
CHEMICAL (MIXED)



dl-α-tocopheryl phosphate has a growth acceleration effect on domestic fowl. Also was confirmed, that in all investigated animals dl-α-tocopheryl phosphate has an ability to being converted into vitamin E.
Status:
US Previously Marketed
Source:
Solution of Ferric Acetate N.F.
(1921)
Source URL:
First marketed in 1921
Source:
Solution of Ferric Acetate N.F.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Ferric acetate is the coordination compound more commonly known as "basic iron acetate". Used in the textile industry as a mordant in dyeing and printing, and for the weighting of silk and felt; as wood preservative; in leather dyes. Ferric acetate method is directly applicable to tissue cholesterol analysis (method of Parekh and Jung).
Phenylmercuric ammonium acetate is a fungicide and bactericide. It is used for the seed treatment.

Showing 1961 - 1970 of 2850 results