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Details

Stereochemistry ACHIRAL
Molecular Formula C6H5Hg.C2H3O2
Molecular Weight 336.74
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PHENYLMERCURIC ACETATE

SMILES

CC([O-])=O.[Hg+]C1=CC=CC=C1

InChI

InChIKey=XEBWQGVWTUSTLN-UHFFFAOYSA-M
InChI=1S/C6H5.C2H4O2.Hg/c1-2-4-6-5-3-1;1-2(3)4;/h1-5H;1H3,(H,3,4);/q;;+1/p-1

HIDE SMILES / InChI

Description

Phenylmercuric ammonium acetate is a fungicide and bactericide. It is used for the seed treatment.

CNS Activity

Originator

Approval Year

1921
1467
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8297
Inhibitor
8297
Inhibitor
8297
Inhibitor
8297
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
Basic research
Unknown

Approved Use

Unknown
Curative
Phase I
428
Unknown

Approved Use

Unknown
Preventing
Approved
8429
Volpar gel

Approved Use

Spermicide

Launch Date

-1.04137923E12
Doses

Doses

DosePopulationAdverse events​
0.01 % 1 times / day multiple, topical
Dose: 0.01 %, 1 times / day
Route: topical
Route: multiple
Dose: 0.01 %, 1 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/8112079
healthy, 54 years
n = 1
Health Status: healthy
Age Group: 54 years
Sex: F
Population Size: 1
Sources:
https://pubmed.ncbi.nlm.nih.gov/8112079
Disc. AE: Contact urticaria...
AEs leading to
discontinuation/dose reduction:
Contact urticaria
Sources:
https://pubmed.ncbi.nlm.nih.gov/8112079
AEs

AEs

AESignificanceDosePopulation
Contact urticaria Disc. AE
0.01 % 1 times / day multiple, topical
Dose: 0.01 %, 1 times / day
Route: topical
Route: multiple
Dose: 0.01 %, 1 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/8112079
healthy, 54 years
n = 1
Health Status: healthy
Age Group: 54 years
Sex: F
Population Size: 1
Sources:
https://pubmed.ncbi.nlm.nih.gov/8112079
Overview

Overview

CYP3A4CYP2C9CYP2D6hERG
activator
80
activator
22
activator
23

OverviewOther

Other InhibitorOther SubstrateOther Inducer
Drug as perpetrator​

Drug as perpetrator​

TargetModalityActivityMetaboliteClinical evidence
CYP2C19
1553
 yes [Activation 1 uM]
CYP3A4
1925
 yes [Activation 1.8 uM]
CYP1A1
218
 yes [Activation 22 uM]
CYP1A2
1692
 yes [Activation 3.2 uM]
CYP2D6
1891
 yes [Activation 4.5 uM]
CYP2C9
1819
 yes [Activation 8.9 uM]
Sourcing

Sourcing

Vendor/AggregatorIDURL
3B Scientific (Wuhan) Corp
3B3-034131
http://www.3bsc.com/index/pro_info.php?id=56000
AK Scientific, Inc. (AKSCI)
8055AF
http://www.aksci.com/item_detail.php?cat=8055AF
Alfa Aesar
37125
https://www.alfa.com/en/catalog/037125/
Alfa Chemistry
ACM62384
https://materials.alfachemic.com/product/phenylmercuric-acetate-cas-62-38-4-329208.html
ChemExper Chemical Directory
HmtD`HX@kIDhhdYVhF@@@@
ChemMol
99117839
http://www.chemmol.com/chemmol/99117839.html
Chemieliva Pharmaceutical Co., Ltd
PBCM0699947
NovoSeek
16682730
PubChem
16682730
https://pubchem.ncbi.nlm.nih.gov/compound/16682730
Sigma-Aldrich
P27127_ALDRICH
https://www.sigmaaldrich.com/catalog/product/aldrich/p27127?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
Sigma-Aldrich
79120_SIAL
https://www.sigmaaldrich.com/catalog/product/sial/79120?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
VladaChem
VL164284
https://www.vladachem.com/product.php?products=62-38-4
abcr GmbH
AB121008
http://www.abcr.de/shop/en/AB121008
iChemical
EBD578391
http://www.ichemical.com/products/62-38-4.html?utm_source=PubChem&utm_medium=website&utm_campaign=product%20catalogs
PubMed

PubMed

TitleDatePubMed
Mercury (Hg) and lead (Pb) in interior and exterior New Orleans house paint films.
2008 Jun
The role of mycelium production and a MAPK-mediated immune response in the C. elegans-Fusarium model system.
2012 Jul
Patents

Patents

20060008862
10
7488721
2
US3068142
2

Sample Use Guides

In Vivo Use Guide
Contraceptive suppositories or gel
Route of Administration: Vaginal
In Vitro Use Guide
MIC₉₀s of phenylmercuric acetate were 0.0156, 0.0156, 0.0156 and 0.0156 mg/L for Fusarium spp., Aspergillus spp., A. alternata and other pathogens, respectively.
Name Type Language
PHENYLMERCURIC ACETATE
EP   HSDB   II   MART.   MI   VANDF   WHO-DD  
Common Name English
PHENYLMERCURIC ACETATE [EP IMPURITY]
Common Name English
PHENYLMERCURIC ACETATE [II]
Common Name English
MERCURY, (ACETATO-O)PHENYL-
Common Name English
PHENYLMERCURIC ACETATE [HSDB]
Common Name English
PHENYLMERCURIC ACETATE [MI]
Common Name English
PHENYL MERCURIC ACETATE
INCI  
INCI  
Official Name English
Phenylmercuric acetate [WHO-DD]
Common Name English
PHENYLMERCURY ACETATE [ISO]
Common Name English
PHENYLMERCURIC ACETATE [VANDF]
Common Name English
PHENYLMERCURIC ACETATE [MART.]
Common Name English
PHENYL MERCURIC ACETATE [INCI]
Common Name English
PHENYLMERCURY ACETATE
ISO  
Systematic Name English
(Acetato)phenylmercury
Common Name English
PHENYLMERCURIC ACETATE [EP MONOGRAPH]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 66003
Created by admin on Fri Dec 15 15:05:15 UTC 2023 , Edited by admin on Fri Dec 15 15:05:15 UTC 2023
NCI_THESAURUS C737
Created by admin on Fri Dec 15 15:05:15 UTC 2023 , Edited by admin on Fri Dec 15 15:05:15 UTC 2023
Code System Code Type Description
ECHA (EC/EINECS)
200-532-5
Created by admin on Fri Dec 15 15:05:15 UTC 2023 , Edited by admin on Fri Dec 15 15:05:15 UTC 2023
PRIMARY
SMS_ID
100000079434
Created by admin on Fri Dec 15 15:05:15 UTC 2023 , Edited by admin on Fri Dec 15 15:05:15 UTC 2023
PRIMARY
NCI_THESAURUS
C84050
Created by admin on Fri Dec 15 15:05:15 UTC 2023 , Edited by admin on Fri Dec 15 15:05:15 UTC 2023
PRIMARY
WIKIPEDIA
Phenylmercury acetate
Created by admin on Fri Dec 15 15:05:15 UTC 2023 , Edited by admin on Fri Dec 15 15:05:15 UTC 2023
PRIMARY
CHEBI
27684
Created by admin on Fri Dec 15 15:05:15 UTC 2023 , Edited by admin on Fri Dec 15 15:05:15 UTC 2023
PRIMARY
EVMPD
SUB14841MIG
Created by admin on Fri Dec 15 15:05:15 UTC 2023 , Edited by admin on Fri Dec 15 15:05:15 UTC 2023
PRIMARY
HSDB
1670
Created by admin on Fri Dec 15 15:05:15 UTC 2023 , Edited by admin on Fri Dec 15 15:05:15 UTC 2023
PRIMARY
MESH
D010662
Created by admin on Fri Dec 15 15:05:15 UTC 2023 , Edited by admin on Fri Dec 15 15:05:15 UTC 2023
PRIMARY
PUBCHEM
9905811
Created by admin on Fri Dec 15 15:05:15 UTC 2023 , Edited by admin on Fri Dec 15 15:05:15 UTC 2023
PRIMARY
DAILYMED
OSX88361UX
Created by admin on Fri Dec 15 15:05:15 UTC 2023 , Edited by admin on Fri Dec 15 15:05:15 UTC 2023
PRIMARY
MERCK INDEX
m8681
Created by admin on Fri Dec 15 15:05:15 UTC 2023 , Edited by admin on Fri Dec 15 15:05:15 UTC 2023
PRIMARY Merck Index
FDA UNII
OSX88361UX
Created by admin on Fri Dec 15 15:05:15 UTC 2023 , Edited by admin on Fri Dec 15 15:05:15 UTC 2023
PRIMARY
EPA CompTox
DTXSID7021150
Created by admin on Fri Dec 15 15:05:15 UTC 2023 , Edited by admin on Fri Dec 15 15:05:15 UTC 2023
PRIMARY
CAS
62-38-4
Created by admin on Fri Dec 15 15:05:15 UTC 2023 , Edited by admin on Fri Dec 15 15:05:15 UTC 2023
PRIMARY
ALANWOOD
phenylmercury acetate
Created by admin on Fri Dec 15 15:05:15 UTC 2023 , Edited by admin on Fri Dec 15 15:05:15 UTC 2023
PRIMARY
RXCUI
1426778
Created by admin on Fri Dec 15 15:05:15 UTC 2023 , Edited by admin on Fri Dec 15 15:05:15 UTC 2023
PRIMARY RxNorm
NIH
NCATS
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