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Details

Stereochemistry ACHIRAL
Molecular Formula C6H5Hg.C2H3O2
Molecular Weight 336.74
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PHENYLMERCURIC ACETATE

SMILES

CC([O-])=O.[Hg+]C1=CC=CC=C1

InChI

InChIKey=XEBWQGVWTUSTLN-UHFFFAOYSA-M
InChI=1S/C6H5.C2H4O2.Hg/c1-2-4-6-5-3-1;1-2(3)4;/h1-5H;1H3,(H,3,4);/q;;+1/p-1

HIDE SMILES / InChI
Molecular Formula C6H5Hg
Molecular Weight 277.69
Charge 1
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C2H3O2
Molecular Weight 59.044
Charge -1
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Phenylmercuric ammonium acetate is a fungicide and bactericide. It is used for the seed treatment.

CNS Activity

CNS Non-penetrant
1,014

Originator

British Drug Houses
4

Approval Year

1921
1,467

Targets

Primary TargetPharmacologyConditionPotency
Fusarium sp.
2
Inhibitor
8,297
Aspergillus sp.
2
Inhibitor
8,297
platelet aggregation
76
Inhibitor
8,297
Neisseria gonorrhoeae
5
Inhibitor
8,297

Conditions

ConditionModalityTargetsHighest PhaseProduct
Ocular fungal infections
2
 Curative
Basic research
Unknown
Gonorrhea
30
 Curative
Phase I
428
Unknown
Pregnancy
65
 Preventing
Approved
8,429
Volpar gel

Doses

AEs

Overview

CYP3A4CYP2C9CYP2D6hERG
activator
80
activator
22
activator
23

OverviewOther

Other InhibitorOther SubstrateOther Inducer

Drug as perpetrator​

PubMed

Patents

20060008862
10
7488721
2
US3068142
2

Sample Use Guides

In Vivo Use Guide
Contraceptive suppositories or gel
Route of Administration: Vaginal
In Vitro Use Guide
MIC₉₀s of phenylmercuric acetate were 0.0156, 0.0156, 0.0156 and 0.0156 mg/L for Fusarium spp., Aspergillus spp., A. alternata and other pathogens, respectively.
Substance Class Chemical
Record UNII
OSX88361UX
Record Status Validated (UNII)
Record Version
NIH
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