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Details

Stereochemistry ACHIRAL
Molecular Formula C6H5Hg.C2H3O2
Molecular Weight 336.74
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PHENYLMERCURIC ACETATE

SMILES

CC([O-])=O.[Hg+]C1=CC=CC=C1

InChI

InChIKey=XEBWQGVWTUSTLN-UHFFFAOYSA-M
InChI=1S/C6H5.C2H4O2.Hg/c1-2-4-6-5-3-1;1-2(3)4;/h1-5H;1H3,(H,3,4);/q;;+1/p-1

HIDE SMILES / InChI
Molecular Formula C2H3O2
Molecular Weight 59.044
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C6H5Hg
Molecular Weight 277.69
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Phenylmercuric ammonium acetate is a fungicide and bactericide. It is used for the seed treatment.

CNS Activity

Originator

Approval Year

1921
1468
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8504
Inhibitor
8504
Inhibitor
8504
Inhibitor
8504
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
Basic research
Unknown

Approved Use

Unknown
Curative
Phase I
438
Unknown

Approved Use

Unknown
Preventing
Approved
8583
Volpar gel

Approved Use

Spermicide

Launch Date

1936
Doses

Doses

DosePopulationAdverse events​
0.01 % 1 times / day multiple, topical
Dose: 0.01 %, 1 times / day
Route: topical
Route: multiple
Dose: 0.01 %, 1 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/8112079
healthy, 54 years
Health Status: healthy
Age Group: 54 years
Sex: F
Sources:
https://pubmed.ncbi.nlm.nih.gov/8112079
Disc. AE: Contact urticaria...
AEs leading to
discontinuation/dose reduction:
Contact urticaria
Sources:
https://pubmed.ncbi.nlm.nih.gov/8112079
AEs

AEs

AESignificanceDosePopulation
Contact urticaria Disc. AE
0.01 % 1 times / day multiple, topical
Dose: 0.01 %, 1 times / day
Route: topical
Route: multiple
Dose: 0.01 %, 1 times / day
Sources:
https://pubmed.ncbi.nlm.nih.gov/8112079
healthy, 54 years
Health Status: healthy
Age Group: 54 years
Sex: F
Sources:
https://pubmed.ncbi.nlm.nih.gov/8112079
Overview

Overview

CYP3A4CYP2C9CYP2D6hERG
activator
150
activator
23
activator
25

OverviewOther

Other InhibitorOther SubstrateOther Inducer
Drug as perpetrator​

Drug as perpetrator​

TargetModalityActivityMetaboliteClinical evidence
CYP2C19
2141
 yes [Activation 1 uM]
CYP3A4
2633
 yes [Activation 1.8 uM]
CYP1A1
272
 yes [Activation 22 uM]
CYP1A2
2333
 yes [Activation 3.2 uM]
CYP2D6
2546
 yes [Activation 4.5 uM]
CYP2C9
2497
 yes [Activation 8.9 uM]
Sourcing

Sourcing

Vendor/AggregatorIDURL
3B Scientific (Wuhan) Corp
3B3-034131
http://www.3bsc.com/index/pro_info.php?id=56000
abcr GmbH
AB121008
http://www.abcr.de/shop/en/AB121008
AK Scientific, Inc. (AKSCI)
8055AF
http://www.aksci.com/item_detail.php?cat=8055AF
Alfa Aesar
37125
https://www.alfa.com/en/catalog/037125/
Alfa Chemistry
ACM62384
https://materials.alfachemic.com/product/phenylmercuric-acetate-cas-62-38-4-329208.html
ChemExper Chemical Directory
HmtD`HX@kIDhhdYVhF@@@@
Chemieliva Pharmaceutical Co., Ltd
PBCM0699947
ChemMol
99117839
http://www.chemmol.com/chemmol/99117839.html
iChemical
EBD578391
http://www.ichemical.com/products/62-38-4.html?utm_source=PubChem&utm_medium=website&utm_campaign=product%20catalogs
NovoSeek
16682730
PubChem
16682730
https://pubchem.ncbi.nlm.nih.gov/compound/16682730
Sigma-Aldrich
79120_SIAL
https://www.sigmaaldrich.com/catalog/product/sial/79120?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
Sigma-Aldrich
P27127_ALDRICH
https://www.sigmaaldrich.com/catalog/product/aldrich/p27127?utm_source=pubchem&utm_campaign=pubchem_2017&utm_medium=referral
VladaChem
VL164284
https://www.vladachem.com/product.php?products=62-38-4
PubMed

PubMed

TitleDatePubMed
A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors.
2015-09
Population-based in vitro hazard and concentration-response assessment of chemicals: the 1000 genomes high-throughput screening study.
2015-05
The antifungal properties of chlorhexidine digluconate and cetylpyrinidinium chloride on oral Candida.
2012-07
The role of mycelium production and a MAPK-mediated immune response in the C. elegans-Fusarium model system.
2012-07
Mercury (Hg) and lead (Pb) in interior and exterior New Orleans house paint films.
2008-06
Characterization and inhibition of SARS-coronavirus main protease.
2006
[Contact sensitization to pharmaceutic aids in dermatologic cosmetic and external use preparations].
2004-05
[Contact eczema caused by pesticides in East Germany].
1989
Bacterial organomercurial lyase: overproduction, isolation, and characterization.
1986-11-04
Patents

Patents

20060008862
10
7488721
2
US3068142
2

Sample Use Guides

In Vivo Use Guide
Contraceptive suppositories or gel
Route of Administration: Vaginal
In Vitro Use Guide
MIC₉₀s of phenylmercuric acetate were 0.0156, 0.0156, 0.0156 and 0.0156 mg/L for Fusarium spp., Aspergillus spp., A. alternata and other pathogens, respectively.
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:45:58 GMT 2025
Edited
by admin
on Mon Mar 31 17:45:58 GMT 2025
Record UNII
OSX88361UX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PHENYLMERCURIC ACETATE
EP   HSDB   II   MART.   MI   VANDF   WHO-DD  
Common Name English
PHENYL MERCURIC ACETATE
INCI  
INCI  
Preferred Name English
PHENYLMERCURIC ACETATE [EP IMPURITY]
Common Name English
PHENYLMERCURIC ACETATE [II]
Common Name English
MERCURY, (ACETATO-O)PHENYL-
Common Name English
PHENYLMERCURIC ACETATE [HSDB]
Common Name English
PHENYLMERCURIC ACETATE [MI]
Common Name English
Phenylmercuric acetate [WHO-DD]
Common Name English
PHENYLMERCURY ACETATE [ISO]
Common Name English
PHENYLMERCURIC ACETATE [VANDF]
Common Name English
PHENYLMERCURIC ACETATE [MART.]
Common Name English
PHENYLMERCURY ACETATE
ISO  
Systematic Name English
(Acetato)phenylmercury
Common Name English
PHENYLMERCURIC ACETATE [EP MONOGRAPH]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 66003
Created by admin on Mon Mar 31 17:45:58 GMT 2025 , Edited by admin on Mon Mar 31 17:45:58 GMT 2025
NCI_THESAURUS C737
Created by admin on Mon Mar 31 17:45:58 GMT 2025 , Edited by admin on Mon Mar 31 17:45:58 GMT 2025
Code System Code Type Description
ECHA (EC/EINECS)
200-532-5
Created by admin on Mon Mar 31 17:45:58 GMT 2025 , Edited by admin on Mon Mar 31 17:45:58 GMT 2025
PRIMARY
SMS_ID
100000079434
Created by admin on Mon Mar 31 17:45:58 GMT 2025 , Edited by admin on Mon Mar 31 17:45:58 GMT 2025
PRIMARY
NCI_THESAURUS
C84050
Created by admin on Mon Mar 31 17:45:58 GMT 2025 , Edited by admin on Mon Mar 31 17:45:58 GMT 2025
PRIMARY
WIKIPEDIA
Phenylmercury acetate
Created by admin on Mon Mar 31 17:45:58 GMT 2025 , Edited by admin on Mon Mar 31 17:45:58 GMT 2025
PRIMARY
CHEBI
27684
Created by admin on Mon Mar 31 17:45:58 GMT 2025 , Edited by admin on Mon Mar 31 17:45:58 GMT 2025
PRIMARY
EVMPD
SUB14841MIG
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PRIMARY
HSDB
1670
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PRIMARY
MESH
D010662
Created by admin on Mon Mar 31 17:45:58 GMT 2025 , Edited by admin on Mon Mar 31 17:45:58 GMT 2025
PRIMARY
PUBCHEM
9905811
Created by admin on Mon Mar 31 17:45:58 GMT 2025 , Edited by admin on Mon Mar 31 17:45:58 GMT 2025
PRIMARY
DAILYMED
OSX88361UX
Created by admin on Mon Mar 31 17:45:58 GMT 2025 , Edited by admin on Mon Mar 31 17:45:58 GMT 2025
PRIMARY
MERCK INDEX
m8681
Created by admin on Mon Mar 31 17:45:58 GMT 2025 , Edited by admin on Mon Mar 31 17:45:58 GMT 2025
PRIMARY Merck Index
FDA UNII
OSX88361UX
Created by admin on Mon Mar 31 17:45:58 GMT 2025 , Edited by admin on Mon Mar 31 17:45:58 GMT 2025
PRIMARY
EPA CompTox
DTXSID7021150
Created by admin on Mon Mar 31 17:45:58 GMT 2025 , Edited by admin on Mon Mar 31 17:45:58 GMT 2025
PRIMARY
CAS
62-38-4
Created by admin on Mon Mar 31 17:45:58 GMT 2025 , Edited by admin on Mon Mar 31 17:45:58 GMT 2025
PRIMARY
ALANWOOD
phenylmercury acetate
Created by admin on Mon Mar 31 17:45:58 GMT 2025 , Edited by admin on Mon Mar 31 17:45:58 GMT 2025
PRIMARY
RXCUI
1426778
Created by admin on Mon Mar 31 17:45:58 GMT 2025 , Edited by admin on Mon Mar 31 17:45:58 GMT 2025
PRIMARY RxNorm
NIH
NCATS
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