U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 141 - 150 of 2893 results

Status:
Investigational
Source:
NCT01644682: Phase 3 Interventional Completed Cost-effective and Sustainable Vector Control Methods Will be Established to Reduce VL in India, Bangladesh and Nepal
(2012)
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Status:
Investigational
Source:
INN:quintiofos
Source URL:

Class (Stereo):
CHEMICAL (UNKNOWN)

Quintiofos is phosphonothioic ester derivative patented by Farbenfabriken Bayer A.-G. as insecticide and ascaricide, particularly against parasites of the larger animals.
Status:
Investigational
Source:
JAN:PROPETAMPHOS [JAN]
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Status:
Investigational
Source:
INN:niclofolan
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Niclofolan (bayer 9015, Bilevon) is a biphenyl anthelmintic compound. Niclofolan is used orally towards the treatment of Fasciola hepatica infection. Niclofolan therapy achieved elimination of eggs from the feces and normalization of eosinophil counts, liver enzymes and Fasciola titers, suggesting eradication of biliary flukes. Niclofolan has also been used in the treatment of Paragonimus westermani in dogs and cats and P. iloktsuenensis in rats. It was proved that administration of daily dose of 1.0 mg/kg body weight for 3 days or in 2 doses of 2.0 mg/kg body weight by alternate days were evidently effective for the infected dogs, cats and rats with the lung flukes, and toxic manifestations were not found.
Status:
Investigational
Source:
INN:diprogulic acid [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Diprogulic acid (Dikegulac) is used as a precursor in vitamin C synthesis. It is plant growth regulator for hedges. Dikegulac is used to differentially kill terminal apices, and it analogously inhibits basic metabolic functions in dividing cells, but not stationary cells, in suspension culture. At the lowest concentrations, dikegulac partially suppresses division of the isolated tobacco protoplasts. Higher concentrations are required to produce visual cytoplasmic damage to the protoplasts, which probably first occurs at the level of the plasmalemma, as the vacuoles can be released intact. Later, tonoplast disruption occurs. It does not inhibit mature leaves.
Status:
Investigational
Source:
INN:crufomate
Source URL:

Class (Stereo):
CHEMICAL (UNKNOWN)

Crufomate is an insecticide and antihelmintic drug which acts by inhibition of acetylcholinesterase. Crufomate was used on or in cattle, sheep, and goats to control internal cattle grubs and external horn flies and cattle lice. Crufomate is administered by injection, oral administration, and spraying. For the treatment of internal helminth parasites, crufomate is administered by the oral drench directly into the rumen.
Status:
Investigational
Source:
INN:etofenprox
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Etofenprox is a synthetic pyrethroid insecticide compound used in agricultural production. Etofenprox acts on the nervous system of insects by disrupting their neuron sodium channels. Etofenprox is a contact-kill adulticide used to control a wide variety of insects including weevils, beetles, aphids, moths, whiteflies, thrips, borers, fleas and mosquitoes. Etofenprox is well tolerated by mammals, including cats, and is environmentally friendly.
Status:
Investigational
Source:
INN:dicloralurea [INN]
Source URL:

Class (Stereo):
CHEMICAL (MIXED)

Conditions:

Dicloralurea is a herbicide and veterinary food additive that inhibits methane production in herbicide ruminants. It acts as a growth stimulant and now superseded.
Status:
Investigational
Source:
INN:bromofos
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Bromofos is an organic thiophosphate used as pesticide and insecticide for apple-pest control. Bromophos possesses remarkable stability in alkaline media and extremely low mammalian toxicity. The oral toxicity for small rodents is 3.75 to 13.4 mg/kg. body wt. Bromofos acts as contact and stomach poison. Very good efficacy is obtained against flies and their larvae, especially against parasitic species on sheep. Bromopros in sheep dip soln. is as effective as diazinon. It is effective in stables for fly control, depending on the surface, for up to 14 weeks.
Status:
Investigational
Source:
NCT02883751: Not Applicable Interventional Withdrawn Diabetes Mellitus
(2017)
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)