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Search results for "EPA PESTICIDE" in comments (approximate match)
Status:
Investigational
Source:
NCT01827605: Phase 3 Interventional Active, not recruiting Relapsed Follicular Lymphoma
(2012)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Tricyclazole is a systemic fungicide for control of Pyricularia oryzae on rice. Tricyclazole protects plants from infection by P. oryzae by preventing penetration of the epidermis by the fungus. The compound acts by inhibiting melanization within the appressorium, thus causing a lack of rigidity in the appressorial wall. Tricyclazole has no apparent effect on spore germination although sporulation is reduced. Tricyclazole is not curative but is protective in its activity. Tricyclazole can influence the pathogenic ability of aspergillus aculeatus by damaging the cell structure of hyphae and conidia, reducing the melanin production, and altering the expression of pathogenic-related gene. Tricyclazole toxin can impair testosterone secretion and the testicular structure in mice, leaving an adversely effect on sperm production system.
Status:
Investigational
Source:
NCT03513159: Not Applicable Interventional Completed Geriatric Patients in the Transition From Hospital to Home
(2018)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Triclopyr-butotyl is an ester form of selective systemic herbicide triclopyr. Prolonged or frequently repeated skin contact with triclopyr-butotyl may cause allergic skin reactions in some individuals. Animal and in-vitro genetic studies were negative for triclopyr-butotyl. Triclopyr-butotyl did not cause cancer in laboratory animals.
Status:
Investigational
Source:
JAN:CHLORPYRIFOS-METHYL [JAN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Chlorpyrifos-methyl is a broad-spectrum organophosphorous insecticide and potential toxic pollutant widely used in agriculture and effective against a wide range of insect pests in commercial importance crops. Chlorpyrifos-methyl have endocrine disruption activity, especially anti-androgenic effects and Chlorpyrifos-methyl administration leads to hepatotoxicity and neurotoxicity in mammals. The fish exposed to chlorpyrifos-methyl exhibited behavioral changes in the form of neurotoxin toxicity: less general activity than control group, loss of equilibrium, erratic swimming and staying motionless at a certain location
Status:
Investigational
Source:
NCT04317417: Not Applicable Interventional Active, not recruiting Cancer
(2022)
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Bifenthrin is a pyrethroid insecticide used in urban and agricultural applications. Bifenthrin is a broad-spectrum insecticide that modifies voltage-gated ion channels disrupting the normal function of nerve cells. In May 2010 EU Commission withdrawn plant protection products containing bifenthrin.
Status:
Investigational
Source:
INN:triclofenol piperazine [INN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
2,4,5-Trichlorophenol is a grey flake or needle-shaped solid. It is used as an intermediate in the manufacture of the herbicide 2,4,5-Trichlorophenoxyacetic Acid (2,4,5-T) and as a fungicide and bactericide. 2,4,5-trichlorophenol (triclofenol piperazine, Ranestol) is an antifungal agent, which was also used against light hookworm infections. Thirty persons who were positive for hookworm eggs in their stools were treated with 50 mg/kg of triclofenol piperazine dissolved in 5 per cent polyethylene glycol Ranestol® in soft gelatin capsules. Nineteen of these showed 77 to 100 % reduction in egg count average when compared with the pre-treatment counts. Side reactions were limited to mild and transient nausea in 23, vomiting in 7, transient abdominal cramps and headache in 2 each. 2,4,5-trichlorophenol complexed with dicyclohexylamine was used for treatment of experimental mycosis. From the mycological and clinical evaluation the conclusion can be drawn that the effect of phenol in lipophilic ointment is comparable to that of clotrimazole.
Status:
Investigational
Source:
NCT04182126: Not Applicable Interventional Completed LLIN, PBO LLIN, IRS, Larviciding
(2019)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Class (Stereo):
CHEMICAL (ACHIRAL)
Guanoctine was studied as an antihypertensive agent.
Status:
Investigational
Source:
NCT03658096: Not Applicable Interventional Enrolling by invitation Distal Radioulnar Joint Sprain
(2017)
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Status:
Investigational
Class (Stereo):
CHEMICAL (ABSOLUTE)
Demiditraz is used in veterinary as acaricide/tick repellant.
Status:
Investigational
Source:
INN:bromociclen [INN]
Source URL:
Class (Stereo):
CHEMICAL (EPIMERIC)
Conditions:
Bromociclen (5-(Bromomethyl)-1,2,3,4,7,7-hexachlorobicyclo[2.2.1]hept-2-ene; 5-(Bromomethyl)-1,2,3,4,7,7-hexachloro-2-norbornene) is a halogenated bicyclic insecticide. Bromociclen is used for the control of stored-product insects as well as against ecto-parasites.