Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C7H7Cl3NO3PS |
| Molecular Weight | 322.533 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COP(=S)(OC)OC1=C(Cl)C=C(Cl)C(Cl)=N1
InChI
InChIKey=HRBKVYFZANMGRE-UHFFFAOYSA-N
InChI=1S/C7H7Cl3NO3PS/c1-12-15(16,13-2)14-7-5(9)3-4(8)6(10)11-7/h3H,1-2H3
| Molecular Formula | C7H7Cl3NO3PS |
| Molecular Weight | 322.533 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Chlorpyrifos-methyl is a broad-spectrum organophosphorous insecticide and potential toxic pollutant widely used in agriculture and effective against a wide range of insect pests in commercial importance crops. Chlorpyrifos-methyl have endocrine disruption activity, especially anti-androgenic effects and Chlorpyrifos-methyl administration leads to hepatotoxicity and neurotoxicity in mammals. The fish exposed to chlorpyrifos-methyl exhibited behavioral changes in the form of neurotoxin toxicity: less general activity than control group, loss of equilibrium, erratic swimming and staying motionless at a certain location
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Biochemical mechanisms of resistance in strains of Oryzaephilus surinamensis (Coleoptera: Silvanidae) resistant to malathion and chlorpyrifos-methyl. | 2001 Jun |
|
| Biological monitoring of exposure of the general population to the organophosphorus pesticides chlorpyrifos and chlorpyrifos-methyl by determination of their specific metabolite 3,5,6-trichloro-2-pyridinol. | 2001 Nov |
|
| Analysis of pesticide residues in eggs by direct sample introduction/gas chromatography/tandem mass spectrometry. | 2001 Oct |
|
| Electrochemical bioassay for the investigation of chlorpyrifos-methyl in vine samples. | 2002 Dec 4 |
|
| Reaction of chlorpyrifos-methyl in aqueous hydrogen sulfide/bisulfide solutions. | 2003 Mar 26 |
|
| Topical applications of pyrethroid and organophosphate mixtures revealed positive interactions against pyrethroid-resistant Anopheles gambiae. | 2004 Dec |
|
| Impact of residual spraying of Reldan against Anopheles culicifacies in selected villages of District Ghaziabad (Uttar pradesh), India. | 2004 Sep-Dec |
|
| Investigation of acute toxicity of chlorpyrifos-methyl on Nile tilapia (Oreochromis niloticus L.) larvae. | 2005 Apr |
|
| Application of hollow fiber liquid phase microextraction for the determination of insecticides in water. | 2005 Apr 22 |
|
| Pesticide testing on human subjects: weighing benefits and risks. | 2005 Jul |
|
| Chlorpyrifos-methyl dissipation in a small adjacent water body following application to citrus. | 2005 Mar |
|
| A study of the disappearance of pesticides during composting using a gas chromatography-tandem mass spectrometry technique. | 2005 May |
|
| Experimental hut evaluation of bednets treated with an organophosphate (chlorpyrifos-methyl) or a pyrethroid (lambdacyhalothrin) alone and in combination against insecticide-resistant Anopheles gambiae and Culex quinquefasciatus mosquitoes. | 2005 May 26 |
|
| Concentrations of selective metabolites of organophosphorus pesticides in the United States population. | 2005 Nov |
|
| Nucleophilic substitution reactions of chlorpyrifos-methyl with sulfur species. | 2006 Feb 1 |
|
| Exposure to nonpersistent insecticides and male reproductive hormones. | 2006 Jan |
|
| Effect of surface waxes on the persistence of chlorpyrifos-methyl in apples, strawberries and grapefruits. | 2006 Jul |
|
| Biomonitoring of exposure in farmworker studies. | 2006 Jun |
|
| Potential uses of biomonitoring data: a case study using the organophosphorus pesticides chlorpyrifos and malathion. | 2006 Nov |
|
| Quantifying behavioural interactions between humans and mosquitoes: evaluating the protective efficacy of insecticidal nets against malaria transmission in rural Tanzania. | 2006 Nov 10 |
|
| Thyroid hormones in relation to urinary metabolites of non-persistent insecticides in men of reproductive age. | 2006 Oct |
|
| Development and single-laboratory validation of a new gas chromatographic multi-pesticide method of analysis of commercial emulsifiable concentrate formulations containing alachlor, chlorpyrifos methyl, fenthion and trifluralin as active ingredients. | 2006 Oct 6 |
|
| Nucleophilic substitution of phosphorothionate ester pesticides with bisulfide (HS-) and polysulfides (S(n)2-). | 2006 Sep 1 |
|
| Efficacy of bifenthrin-impregnated bednets against Anopheles funestus and pyrethroid-resistant Anopheles gambiae in North Cameroon. | 2006 Sep 11 |
|
| Performance assessment and validation of a paramagnetic particle-based enzyme-linked immunosorbent assay for chlorpyrifos in agricultural runoff waters. | 2007 Aug 8 |
|
| Combined treatments of spinosad and chlorpyrifos-methyl for management of resistant psocid pests (Psocoptera: Liposcelididae) of stored grain. | 2007 Jan |
|
| Safe apples for baby-food production: survey of pesticide treatment regimes leaving minimum residues. | 2007 Jun |
|
| [Determination of organic phosphorus pesticide residues in scallion by gas chromatography coupled with microwave clean-up]. | 2007 May |
|
| Cutinase inhibition by means of insecticidal organophosphates and carbamates. 3. Oxidation of phosphorothionates by chloroperoxidase from Caldariomyces fumago. | 2007 Oct 3 |
|
| Pesticide residues in Italian Ready-Meals and dietary intake estimation. | 2007 Sep-Oct |
|
| Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment. | 2008 |
|
| Dynamics of insecticide resistance in the malaria vector Anopheles gambiae s.l. from an area of extensive cotton cultivation in Northern Cameroon. | 2008 Apr |
|
| Costs and benefits of multiple resistance to insecticides for Culex quinquefasciatus mosquitoes. | 2008 Apr 8 |
|
| Circulating estradiol in men is inversely related to urinary metabolites of nonpersistent insecticides. | 2008 Feb |
|
| Comparison of different extraction methods for the simultaneous determination of pesticide residues in kiwi fruit using gas chromatography-mass spectrometry. | 2008 Jul |
|
| Survey of pesticide residues in imported cereal products (1994.4 approximately 2006.3). | 2008 Jun |
|
| Optimization of separation and detection conditions for the multiresidue analysis of pesticides in grapes by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry. | 2008 May 9 |
|
| Evaluation of working air quality by using semipermeable membrane devices. Analysis of organophosphorus pesticides. | 2008 Sep 19 |
|
| A biomarker validation study of prenatal chlorpyrifos exposure within an inner-city cohort during pregnancy. | 2009 Apr |
|
| Exposure to pesticides residues from consumption of Italian blood oranges. | 2009 Jul |
|
| Impact of food consumption habits on the pesticide dietary intake: comparison between a French vegetarian and the general population. | 2009 Oct |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 17:47:44 GMT 2023
by
admin
on
Fri Dec 15 17:47:44 GMT 2023
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| Record UNII |
O49S38267J
|
| Record Status |
Validated (UNII)
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| Record Version |
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EPA PESTICIDE CODE |
59102
Created by
admin on Fri Dec 15 17:47:44 GMT 2023 , Edited by admin on Fri Dec 15 17:47:44 GMT 2023
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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chlorpyrifos-methyl
Created by
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O49S38267J
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6981
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C163642
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227-011-5
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21803
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60380
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DTXSID6032352
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5598-13-0
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34632
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C007031
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m3465
Created by
admin on Fri Dec 15 17:47:44 GMT 2023 , Edited by admin on Fri Dec 15 17:47:44 GMT 2023
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PRIMARY | Merck Index |