Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C7H7Cl3NO3PS |
| Molecular Weight | 322.533 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COP(=S)(OC)OC1=NC(Cl)=C(Cl)C=C1Cl
InChI
InChIKey=HRBKVYFZANMGRE-UHFFFAOYSA-N
InChI=1S/C7H7Cl3NO3PS/c1-12-15(16,13-2)14-7-5(9)3-4(8)6(10)11-7/h3H,1-2H3
Chlorpyrifos-methyl is a broad-spectrum organophosphorous insecticide and potential toxic pollutant widely used in agriculture and effective against a wide range of insect pests in commercial importance crops. Chlorpyrifos-methyl have endocrine disruption activity, especially anti-androgenic effects and Chlorpyrifos-methyl administration leads to hepatotoxicity and neurotoxicity in mammals. The fish exposed to chlorpyrifos-methyl exhibited behavioral changes in the form of neurotoxin toxicity: less general activity than control group, loss of equilibrium, erratic swimming and staying motionless at a certain location
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Pesticide residues in dried table grapes from the Aegean region of Turkey. | 2010-08 |
|
| Impact of food consumption habits on the pesticide dietary intake: comparison between a French vegetarian and the general population. | 2009-10 |
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| Comparing the inhibitory effects of five protoxicant organophosphates (azinphos-methyl, parathion-methyl, chlorpyriphos-methyl, methamidophos and diazinon) on the spontaneously beating auricle of Sparus aurata: an in vitro study. | 2009-09-14 |
|
| Evaluation of multi-walled carbon nanotubes as solid-phase extraction adsorbents of pesticides from agricultural, ornamental and forestal soils. | 2009-08-11 |
|
| Comparative efficacy of spinosad with conventional acaricides against hard and soft tick populations from Antalya, Turkey. | 2009-07-07 |
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| Exposure to pesticides residues from consumption of Italian blood oranges. | 2009-07 |
|
| Identification and characterization of chlorpyrifos-methyl and 3,5,6-trichloro-2-pyridinol degrading Burkholderia sp. strain KR100. | 2009-07 |
|
| Monitoring of pesticides and heavy metals in cucumber fruits produced from different farming systems. | 2009-05 |
|
| A biomarker validation study of prenatal chlorpyrifos exposure within an inner-city cohort during pregnancy. | 2009-04 |
|
| Solubility and adsorption behaviors of chlorpyriphos-methyl in the presence of surfactants. | 2009-03 |
|
| Development and validation of a multiresidue method for determination of 82 pesticides in water using GC. | 2009-02 |
|
| Semen quality in Peruvian pesticide applicators: association between urinary organophosphate metabolites and semen parameters. | 2008-11-17 |
|
| Mixture for controlling insecticide-resistant malaria vectors. | 2008-11 |
|
| Multiwalled carbon nanotubes as solid-phase extraction materials for the gas chromatographic determination of organophosphorus pesticides in waters. | 2008-10 |
|
| Evidence of increasing Leu-Phe knockdown resistance mutation in Anopheles gambiae from Niger following a nationwide long-lasting insecticide-treated nets implementation. | 2008-09-25 |
|
| Dynamics of multiple insecticide resistance in the malaria vector Anopheles gambiae in a rice growing area in South-Western Burkina Faso. | 2008-09-25 |
|
| Evaluation of working air quality by using semipermeable membrane devices. Analysis of organophosphorus pesticides. | 2008-09-19 |
|
| Comparison of gas chromatography-mass spectrometry and gas chromatography-tandem mass spectrometry with electron ionization and negative-ion chemical ionization for analyses of pesticides at trace levels in atmospheric samples. | 2008-09-09 |
|
| Synthesis and insecticidal activity of new 3-benzylfuran-2-yl N,N,N',N'-tetraethyldiamidophosphate derivatives. | 2008-08 |
|
| Parallel assessment of male reproductive function in workers and wild rats exposed to pesticides in banana plantations in Guadeloupe. | 2008-07-30 |
|
| Comparison of different extraction methods for the simultaneous determination of pesticide residues in kiwi fruit using gas chromatography-mass spectrometry. | 2008-07 |
|
| [Survey of pesticide residues in imported cereal products (1994.4 approximately 2006.3)]. | 2008-06 |
|
| Optimization of separation and detection conditions for the multiresidue analysis of pesticides in grapes by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry. | 2008-05-09 |
|
| Costs and benefits of multiple resistance to insecticides for Culex quinquefasciatus mosquitoes. | 2008-04-08 |
|
| Headspace single-drop microextraction and GC-ECD determination of chlorpyrifos-ethyl in rat liver. | 2008-04 |
|
| Dynamics of insecticide resistance in the malaria vector Anopheles gambiae s.l. from an area of extensive cotton cultivation in Northern Cameroon. | 2008-04 |
|
| Circulating estradiol in men is inversely related to urinary metabolites of nonpersistent insecticides. | 2008-02 |
|
| Solid-phase microextraction-liquid chromatography-mass spectrometry applied to the analysis of insecticides in honey. | 2008-01 |
|
| Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment. | 2008 |
|
| Simple one-step extraction and cleanup by pressurized liquid extraction for gas chromatographic-mass spectrometric determination of pesticides in green leafy vegetables. | 2007-12-21 |
|
| Determination of pesticides in milk-based infant formulas by pressurized liquid extraction followed by gas chromatography tandem mass spectrometry. | 2007-11 |
|
| Cutinase inhibition by means of insecticidal organophosphates and carbamates. 3. Oxidation of phosphorothionates by chloroperoxidase from Caldariomyces fumago. | 2007-10-03 |
|
| Interdependence of domestic malaria prevention measures and mosquito-human interactions in urban Dar es Salaam, Tanzania. | 2007-09-19 |
|
| Pesticide residues in Italian Ready-Meals and dietary intake estimation. | 2007-09-01 |
|
| Characterization of insensitive acetylcholinesterase (ace-1R) in Anopheles gambiae (Diptera: Culicidae): resistance levels and dominance. | 2007-09 |
|
| Exploring the contributions of bed nets, cattle, insecticides and excitorepellency to malaria control: a deterministic model of mosquito host-seeking behaviour and mortality. | 2007-09 |
|
| Performance assessment and validation of a paramagnetic particle-based enzyme-linked immunosorbent assay for chlorpyrifos in agricultural runoff waters. | 2007-08-08 |
|
| Multiresidue analysis of four pesticide residues in water dropwort (Oenanthe javanica) via pressurized liquid extraction, supercritical fluid extraction, and liquid-liquid extraction and gas chromatographic determination. | 2007-08 |
|
| Ovicidal and larvicidal effectiveness of insecticides applied by dipping apples on the small fruit tortrix Grapholita lobarzewskii. | 2007-07 |
|
| Pseudomonas-induced defence molecules in rice plants against leaffolder (Cnaphalocrocis medinalis) pest. | 2007-07 |
|
| Safe apples for baby-food production: survey of pesticide treatment regimes leaving minimum residues. | 2007-06 |
|
| [Determination of organic phosphorus pesticide residues in scallion by gas chromatography coupled with microwave clean-up]. | 2007-05 |
|
| Determination of vapor pressure-temperature relationships of current-use pesticides and transformation products. | 2007-05 |
|
| Reduced efficacy of insecticide-treated nets and indoor residual spraying for malaria control in pyrethroid resistance area, Benin. | 2007-02 |
|
| Combined treatments of spinosad and chlorpyrifos-methyl for management of resistant psocid pests (Psocoptera: Liposcelididae) of stored grain. | 2007-01 |
|
| Quantifying behavioural interactions between humans and mosquitoes: evaluating the protective efficacy of insecticidal nets against malaria transmission in rural Tanzania. | 2006-11-10 |
|
| Evaluation of temephos and chlorpyrifos-methyl against Culex pipiens (Diptera: Culicidae) larvae in septic tanks in Antalya, Turkey. | 2006-11 |
|
| Potential uses of biomonitoring data: a case study using the organophosphorus pesticides chlorpyrifos and malathion. | 2006-11 |
|
| Efficacy of bifenthrin-impregnated bednets against Anopheles funestus and pyrethroid-resistant Anopheles gambiae in North Cameroon. | 2006-09-11 |
|
| Nucleophilic substitution of phosphorothionate ester pesticides with bisulfide (HS-) and polysulfides (S(n)2-). | 2006-09-01 |
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EPA PESTICIDE CODE |
59102
Created by
admin on Mon Mar 31 18:53:05 GMT 2025 , Edited by admin on Mon Mar 31 18:53:05 GMT 2025
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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chlorpyrifos-methyl
Created by
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O49S38267J
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6981
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C163642
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227-011-5
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21803
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60380
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DTXSID6032352
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5598-13-0
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34632
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C007031
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m3465
Created by
admin on Mon Mar 31 18:53:05 GMT 2025 , Edited by admin on Mon Mar 31 18:53:05 GMT 2025
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PRIMARY | Merck Index |
SUBSTANCE RECORD