CRUFOMATE

Details

Stereochemistry	UNKNOWN
Molecular Formula	C12H19ClNO3P
Molecular Weight	291.711
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CNP(=O)(OC)OC1=C(Cl)C=C(C=C1)C(C)(C)C

InChI

InChIKey=BOFHKBLZOYVHSI-UHFFFAOYSA-N

InChI=1S/C12H19ClNO3P/c1-12(2,3)9-6-7-11(10(13)8-9)17-18(15,14-4)16-5/h6-8H,1-5H3,(H,14,15)

HIDE SMILES / InChI

Molecular Formula	C12H19ClNO3P
Molecular Weight	291.711
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7059283 | http://www.inchem.org/documents/jmpr/jmpmono/v068pr11.htm

Crufomate is an insecticide and antihelmintic drug which acts by inhibition of acetylcholinesterase. Crufomate was used on or in cattle, sheep, and goats to control internal cattle grubs and external horn flies and cattle lice. Crufomate is administered by injection, oral administration, and spraying. For the treatment of internal helminth parasites, crufomate is administered by the oral drench directly into the rumen.

Approval Year

PubMed

Title	Date	PubMed
Reactivation of acetylcholinesterase inhibited by methamidophos and analogous (di)methylphosphoramidates.	1982 Jan	7059283
Longitudinal trends in organophosphate incidents reported to the National Pesticide Information Center, 1995-2007.	2009 Apr 20	19379510

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:20:43 GMT 2023` Edited by `admin` on `Fri Dec 15 16:20:43 GMT 2023`
Record UNII	V82Q65924L
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CRUFOMATE

Official Name

English

(RS)-(4-TERT-BUTYL-2-CHLOROPHENYL METHYL METHYLPHOSPHORAMIDATE)

Systematic Name

English

4-tert-Butyl-2-chlorophenyl methyl methylphosphoramidate

Systematic Name

English

CRUFOMATE [USAN]

Common Name

English

CRUFOMATE [HSDB]

Common Name

English

2-CHLORO-4-(1,1-DIMETHYLETHYL)PHENYL METHYL METHYLPHOSPHORAMIDATE

Systematic Name

English

crufomate [INN]

Common Name

English

PHOSPHORAMIDIC ACID METHYL-, 2-CHLORO-4-(1,1-DIMETHYLETHYL)PHENYL METHYL ESTER

Common Name

English

NSC-253463

Code

English

CRUFOMATE [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C250