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Development Status
Other
121,663
Possibly Marketed Outside US
12,951
Investigational
12,823
US Approved Rx
4,326
US Previously Marketed
2,847
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Primary Target
Histamine H1 receptor
315
Dopamine D2 receptor
297
DNA
278
Bacterial penicillin-binding protein
233
Serotonin 2a (5-HT2a) receptor
231
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Highest Phase
Approved
8,429
Phase II
1,132
Phase III
656
Not Provided
504
Phase I
428
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Approval Year
Unknown
139,593
1921
1,467
2020
742
2013
596
2012
595
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Unknown
2,578
Pain
614
Cancer
592
Hypertension
567
Breast cancer
434
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Treatment Modality
Primary
9,569
Curative
2,057
Palliative
1,800
Preventing
1,463
Diagnostic
812
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CNS Activity
CNS Active
3,913
CNS Penetrant
2,554
CNS Non-penetrant
1,014
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Originator
Pfizer
420
Eli Lilly
237
Merck
216
GlaxoSmithKline
193
Novartis
173
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Substance Class
Chemical
111,019
Structurally Diverse
27,047
Protein
6,839
Concept
5,871
Mixture
2,929
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INN Stem
Chemical substance(-ine)
330
Monoclonal antibodies(-mab)
199
Tyrosine-kinase inhibitors(-tinib)
71
Peptides and glycopeptides(-tide)
70
Gene Therapy vectors(-vec)
66
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GInAS Tag
KEW
3,301
84371-57-3
1
ATN-3
1
PUBLIC DOMAIN RELEASE
1
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Code System
FDA UNII
150,149
CAS
113,367
PUBCHEM
108,633
EPA CompTox
76,643
ECHA (EC/EINECS)
33,448
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Protein Type
PEPTIDE
917
MONOCLONAL ANTIBODY
901
ENZYME
484
RECEPTOR
369
MONOCLONAL ANTIBODY CONJUGATE
135
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ATC Level 1
NERVOUS SYSTEM
528
ALIMENTARY TRACT AND METABOLISM
511
CARDIOVASCULAR SYSTEM
416
ANTIINFECTIVES FOR SYSTEMIC USE
405
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
353
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ATC Level 2
ANTIBACTERIALS FOR SYSTEMIC USE
250
ANTINEOPLASTIC AGENTS
217
OPHTHALMOLOGICALS
198
PSYCHOLEPTICS
172
CARDIAC THERAPY
124
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ATC Level 3
OTHER ANTINEOPLASTIC AGENTS
139
DIRECT ACTING ANTIVIRALS
88
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
76
ANTITHROMBOTIC AGENTS
76
OTHER BETA-LACTAM ANTIBACTERIALS
73
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ATC Level 4
Antibiotics
52
Other antineoplastic agents
48
Protein kinase inhibitors
47
Enzymes
39
Benzodiazepine derivatives
38
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Substance Form
Principal Form
132,111
Salts, Hydrates, Esters, etc.
18,037
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N,N,N',N'-TETRABUTYL-N,N'-DIETHYL-1,6-HEXANEDIAMINIUM DIHYDROXIDE
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UD39MJ7397
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
N-(2,4-BIS(1-METHYLETHYL)-3-PYRIDINYL)-N'-(1-BUTYL-1,2-DIHYDRO-4-(3-METHOXYPHENYL)-2-OXO-1,8-NAPHTHYRIDIN-3-YL)UREA HYDROCHLORIDE
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9G8S8RL1EO
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
IMINOCTADINE TRIACETATE
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1FTU5HTW7L
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
MS-377
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XJ9U35H4R3
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Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
5-BUTYL-7-CHLORO-6-HYDROXY-11LAMBDA5-PYRIDO(1,2-A)QUINOLIN-11-YLIUM CHLORIDE
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3A275XZP9L
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
ASOXIME CHLORIDE MONOHYDRATE
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FE358MQ67Y
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Acetylcholinesterase
207
DIRHODIUM TETRAACETATE
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NK3058Z56X
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
METHYL VIOLET 6B
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9691711H0F
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
POTASSIUM URANYL SULFATE DIHYDRATE
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EG0NI8388Q
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Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
GEISSOSCHIZOLINE DIHYDROCHLORIDE
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41UDD1CBR4
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Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
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