U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 12101 - 12110 of 12523 results

Status:
US Previously Marketed
Source:
DARTAL 100MG by SEARLE
(1961)
Source URL:
First approved in 1957
Source:
Dartal by Searle
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


THIOPROPAZATE, a phenothiazine derivative, is a typical antipsychotic. It is a prodrug to perphenazine.
Status:
US Previously Marketed
Source:
Leritine by Merck Sharp & Dohme
(1957)
Source URL:
First approved in 1957
Source:
Leritine by Merck Sharp & Dohme
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Aniledrine is a narcotic pain reliver. The drug was prescribed as an analgesic in anaesthesia (Leritine brand name), however, it is no longer available on the market. Although the exact mechanism is not fully understood, aniledrine appears to elicit its action by binding to endorphine receptors in CNS.
Status:
US Previously Marketed
Source:
Zactane by Wyeth
(1957)
Source URL:
First approved in 1957
Source:
Zactane by Wyeth
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)



Ethoheptazine is an analgesic, which belongs to the proheptazine group. It was used either alone (Zactane trade name) or in combination with meprobamate and aspirin (Equagesic) for the pain relief in patients with headache or musculoskeletal disorders. Currently all mediactions containing ethoheptazine are withdrawn from the market. The exact target of ethoheptazine is unknow, but it is believed that it may have modulatory effect on opioid receptors.
Status:
First approved in 1957
Source:
Suavitil by Merck Sharp & Dohme
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Benactyzine, an anticholinergic drug, had been used as an antidepressant in the treatment of depression and associated anxiety. It is no longer used in medicine due to its ineffectiveness but is widely used in scientific research. Benactyzine is a muscarinic antagonist which also inhibits the nicotinic acetylcholine receptor.
Status:
US Previously Marketed
Source:
SUL-SPANSION by SKF
(1961)
Source URL:
First approved in 1956
Source:
Sul-Spansion by Smith Kline & French
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Sulfaethidole is an antibacterial agent, indicated for the treatment of urinary tract infection.
Status:
US Previously Marketed
Source:
Neraval Sodium by Schering
(1956)
Source URL:
First approved in 1956
Source:
Neraval Sodium by Schering
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)


METHITURAL (as sodium salt) is a barbiturate derivative which was used as an ultrashort-acting intravenous anesthetic.
Status:
US Previously Marketed
Source:
Ecolid Chloride by Ciba
(1956)
Source URL:
First approved in 1956
Source:
Ecolid Chloride by Ciba
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

CHLORISONDAMINE is a nicotinic acetylcholine receptor antagonist used as a ganglionic blocking agent in animal research. It was used precedently in the prolonged treatment of hypertension.
Status:
First approved in 1955
Source:
Piptal by Lakeside (MerrellNational)
Source URL:

Class (Stereo):
CHEMICAL (MIXED)



Pipenzolate bromide (JB-323), an anticholinergic agent, which binds to muscarinic acetylcholine receptors as an antagonist. Pipenzolate bromide was studied as an antispasmodic agent, and to treat peptic ulcer.
Status:
US Previously Marketed
Source:
Candettes Lozenges by Pfizer
(1958)
Source URL:
First approved in 1955
Source:
Toclase by Pfizer
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Pentoxyverine is a non-opioid antitussive used to prevent cough caused by common cold. It is used as an active ingredient of several oral over-the-counter cough suppressants alone or in combination with other medications, especially decongestants. Certuss is a combination of pentoxyverine and guaifenesin. Pentoxyverine is FDA pregnancy category C drug. Known as anticonvulsant, and spasmolytic agent.
Status:
US Previously Marketed
Source:
Candettes Lozenges by Pfizer
(1958)
Source URL:
First approved in 1955
Source:
Toclase by Pfizer
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Pentoxyverine is a non-opioid antitussive used to prevent cough caused by common cold. It is used as an active ingredient of several oral over-the-counter cough suppressants alone or in combination with other medications, especially decongestants. Certuss is a combination of pentoxyverine and guaifenesin. Pentoxyverine is FDA pregnancy category C drug. Known as anticonvulsant, and spasmolytic agent.

Showing 12101 - 12110 of 12523 results