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Details

Stereochemistry ACHIRAL
Molecular Formula C10H11N4O2S2.Na
Molecular Weight 306.34
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SULFAETHIDOLE SODIUM

SMILES

[Na+].CCC1=NN=C([N-]S(=O)(=O)C2=CC=C(N)C=C2)S1

InChI

InChIKey=XUGKCAXBCXJYCD-UHFFFAOYSA-N
InChI=1S/C10H11N4O2S2.Na/c1-2-9-12-13-10(17-9)14-18(15,16)8-5-3-7(11)4-6-8;/h3-6H,2,11H2,1H3;/q-1;+1

HIDE SMILES / InChI
Molecular Formula C10H12N4O2S2
Molecular Weight 284.358
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Na
Molecular Weight 22.98976928
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Sulfaethidole is an antibacterial agent, indicated for the treatment of urinary tract infection.

Originator

Approval Year

1956
94
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
Approved
8583
Sul-Spansion

Approved Use

Urinary tract infections

Launch Date

1958
Cmax

Cmax

ValueDoseCo-administeredAnalytePopulation
125 μg/mL
EXPERIMENT
https://doi.org/10.1002/j.1552-4604.1980.tb02547.x
1 g single, oral
dose: 1 g
route of administration: Oral
experiment type: SINGLE
co-administered: DICLOXACILLIN
DICLOXACILLIN
 SULFAETHIDOLE serum
Homo sapiens
population: HEALTHY
age: ADULT
sex: MALE
food status: UNKNOWN
Funbound

Funbound

ValueDoseCo-administeredAnalytePopulation
2.5%
OTHER
https://www.karger.com/Article/Abstract/414185
SULFAETHIDOLE plasma
Homo sapiens
population: UNKNOWN
age: UNKNOWN
sex: UNKNOWN
food status: UNKNOWN
Sourcing

Sourcing

Vendor/AggregatorIDURL
3B Scientific (Wuhan) Corp
3B3-044092
http://www.3bsc.com/index/pro_info.php?id=76291
AA Blocks
AA005SWT
https://www.aablocks.com/goods/Goods/detail?id=AA005SWT
Acadechem
ACDR-030610
http://acadechemical.com/product/43112
AHH Chemical co.,ltd
MT-41364
http://www.ahhchemical.com/product/MT-41364.html
Angene
AGN-PC-0JK7YM
http://www.angenechemical.com/productshow/AGN-PC-0JK7YM.html
Aronis
ARONIS018063
http://www.aronis.ru/store/index.php?main_page=product_info&cPath=1&products_id=1486
Aurum Pharmatech LLC
Z-2045
http://www.Aurumpharmatech.com/Product/ProductDetails/Z_2045
BLD Pharm
BD94193
http://www.bldpharm.com/products/94-19-9.html
ChemMol
80101503
http://www.chemmol.com/chemmol/80101503.html
Chemspace
CSSB00000389409
https://chem-space.com/CSSB00000389409
Clearsynth
CS-M-04062
https://www.clearsynth.com/en/CSM04062.html
eNovation Chemicals
D112666
https://www.enovationchem.com/ProductDetails.asp?ProductID=D112666
Finetech
FT-0676645
http://www.finetechnology-ind.com/prod/detail/pub/94-19-9.html
LGC Standards
DRE-C16990660
https://www.lgcstandards.com/US/en/p/DRE-C16990660
Matrix Scientific
8104
https://www.matrixscientific.com/008104.html
mcule
MCULE-9256808333
https://mcule.com/MCULE-9256808333/
Oakwood
30934
http://www.oakwoodchemical.com/ProductsList.aspx?CategoryID=-2&txtSearch=24812&ExtHyperLink=1
Smolecule
S592133
https://www.smolecule.com/products/s592133
THE BioTek
bt-318415
https://www.thebiotek.com/product/others/bt-318415
PubMed

PubMed

TitleDatePubMed
Pharmacokinetics of sulfaethidole in the rat: nonlinear multicompartment solution.
1982-02
Influence of sulfaethidole on the human pharmacokinetics of dicloxacillin.
1980-08-01
Drug absorption VII: influence of mesenteric blood flow on intestinal drug absorption in dogs.
1975-04
Patents

Patents

US9016221
15
US9775802
2

Sample Use Guides

In Vivo Use Guide
Urinary tract infections Adult: 1.5-4 g/day in 3-4 divided doses. Child: 30-45 mg/kg/day in 4 divided doses.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 22:58:04 GMT 2025
Edited
by admin
on Mon Mar 31 22:58:04 GMT 2025
Record UNII
389JVK194W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SULFAETHIDOLE SODIUM
Common Name English
SULFAETHIDOLE SUDIUM SALT
MI  
Preferred Name English
ETAZOLE SOLUBLE
Common Name English
SULFAETHIDOLE SUDIUM SALT [MI]
Common Name English
SODIUM ETHAZOLE
Common Name English
N1-(5-ETHYL-1,3,4-THIADIAZOL-2-YL)SULFANILAMIDE, SODIUM SALT
Systematic Name English
BENZENESULFONAMIDE, 4-AMINO-N-(5-ETHYL-1,3,4-THIADIAZOL-2-YL)-, MONOSODIUM SALT
Systematic Name English
BENZENESULFONAMIDE, 4-AMINO-N-(5-ETHYL-1,3,4-THIADIAZOL-2-YL)-, SODIUM SALT (1:1)
Systematic Name English
SULFANILAMIDE, N1-(5-ETHYL-1,3,4-THIADIAZOL-2-YL)-, MONOSODIUM SALT
Systematic Name English
SODIUM ETAZOL
Brand Name English
ETHAZOLE SODIUM
Common Name English
NSC-46052
Code English
SODIUM, (N1-(5-ETHYL-1,3,4-THIADIAZOL-2-YL)SULFANILAMIDO)-
Systematic Name English
ETHAZOLE SODIUM SALT
Common Name English
Code System Code Type Description
FDA UNII
389JVK194W
Created by admin on Mon Mar 31 22:58:04 GMT 2025 , Edited by admin on Mon Mar 31 22:58:04 GMT 2025
PRIMARY
NSC
46052
Created by admin on Mon Mar 31 22:58:04 GMT 2025 , Edited by admin on Mon Mar 31 22:58:04 GMT 2025
PRIMARY
PUBCHEM
12835056
Created by admin on Mon Mar 31 22:58:04 GMT 2025 , Edited by admin on Mon Mar 31 22:58:04 GMT 2025
PRIMARY
CAS
1904-95-6
Created by admin on Mon Mar 31 22:58:04 GMT 2025 , Edited by admin on Mon Mar 31 22:58:04 GMT 2025
PRIMARY
Related Record Type Details
Structure of SULFAETHIDOLE
ACTIVE MOIETY
NIH
NCATS
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