SULFAETHIDOLE SODIUM

US Previously Marketed

First approved in 1956

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H11N4O2S2.Na
Molecular Weight	306.34
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].CCC1=NN=C([N-]S(=O)(=O)C2=CC=C(N)C=C2)S1

InChI

InChIKey=XUGKCAXBCXJYCD-UHFFFAOYSA-N

InChI=1S/C10H11N4O2S2.Na/c1-2-9-12-13-10(17-9)14-18(15,16)8-5-3-7(11)4-6-8;/h3-6H,2,11H2,1H3;/q-1;+1

HIDE SMILES / InChI

Molecular Formula	C10H12N4O2S2
Molecular Weight	284.358
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.drugfuture.com/chemdata/sulfaethidole.html | https://www.ndrugs.com/?s=sulfamethizole/sulfaethidole | https://www.ncbi.nlm.nih.gov/pubmed/13636044

Sulfaethidole is an antibacterial agent, indicated for the treatment of urinary tract infection.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Urinary tract infections 205 Sources: https://www.ncbi.nlm.nih.gov/pubmed/13636044 http://pharmabook.net/en/protivomikrobnye--protivoparaz/sinteti4eskie-antibakterialnye/sulfanilamidy/sulfaethidole.html	Curative		Approved 8429	Sul-Spansion Approved Use Urinary tract infections Launch Date 1958

C_max

Value	Dose	Co-administered	Analyte	Population
125 μg/mL EXPERIMENT https://doi.org/10.1002/j.1552-4604.1980.tb02547.x	1 g single, oral dose: 1 g route of administration: Oral experiment type: SINGLE co-administered: DICLOXACILLIN	DICLOXACILLIN	SULFAETHIDOLE serum	Homo sapiens population: HEALTHY age: ADULT sex: MALE food status: UNKNOWN

F_unbound

Value	Dose	Co-administered	Analyte	Population
2.5% OTHER https://www.karger.com/Article/Abstract/414185			SULFAETHIDOLE plasma	Homo sapiens population: UNKNOWN age: UNKNOWN sex: UNKNOWN food status: UNKNOWN

Sourcing

Vendor/Aggregator	ID	URL
3B Scientific (Wuhan) Corp	3B3-044092	http://www.3bsc.com/index/pro_info.php?id=76291
AA Blocks	AA005SWT	https://www.aablocks.com/goods/Goods/detail?id=AA005SWT
AHH Chemical co.,ltd	MT-41364	http://www.ahhchemical.com/product/MT-41364.html
Acadechem	ACDR-030610	http://acadechemical.com/product/43112
Angene	AGN-PC-0JK7YM	http://www.angenechemical.com/productshow/AGN-PC-0JK7YM.html
Aronis	ARONIS018063	http://www.aronis.ru/store/index.php?main_page=product_info&cPath=1&products_id=1486
Aurum Pharmatech LLC	Z-2045	http://www.Aurumpharmatech.com/Product/ProductDetails/Z_2045
BLD Pharm	BD94193	http://www.bldpharm.com/products/94-19-9.html
ChemMol	80101503	http://www.chemmol.com/chemmol/80101503.html
Chemspace	CSSB00000389409	https://chem-space.com/CSSB00000389409
Clearsynth	CS-M-04062	https://www.clearsynth.com/en/CSM04062.html
Finetech	FT-0676645	http://www.finetechnology-ind.com/prod/detail/pub/94-19-9.html
LGC Standards	DRE-C16990660	https://www.lgcstandards.com/US/en/p/DRE-C16990660
Matrix Scientific	8104	https://www.matrixscientific.com/008104.html
Oakwood	30934	http://www.oakwoodchemical.com/ProductsList.aspx?CategoryID=-2&txtSearch=24812&ExtHyperLink=1
Smolecule	S592133	https://www.smolecule.com/products/s592133
THE BioTek	bt-318415	https://www.thebiotek.com/product/others/bt-318415
eNovation Chemicals	D112666	https://www.enovationchem.com/ProductDetails.asp?ProductID=D112666
mcule	MCULE-9256808333	https://mcule.com/MCULE-9256808333/

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

Urinary tract infections Adult: 1.5-4 g/day in 3-4 divided doses. Child: 30-45 mg/kg/day in 4 divided doses.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:00:50 GMT 2023` Edited by `admin` on `Sat Dec 16 10:00:50 GMT 2023`
Record UNII	389JVK194W
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SULFAETHIDOLE SODIUM

Common Name

English

ETAZOLE SOLUBLE

Common Name

English

SULFAETHIDOLE SUDIUM SALT [MI]

Common Name

English

SODIUM ETHAZOLE

Common Name

English

N1-(5-ETHYL-1,3,4-THIADIAZOL-2-YL)SULFANILAMIDE, SODIUM SALT

Systematic Name

English

BENZENESULFONAMIDE, 4-AMINO-N-(5-ETHYL-1,3,4-THIADIAZOL-2-YL)-, MONOSODIUM SALT

Systematic Name

English

BENZENESULFONAMIDE, 4-AMINO-N-(5-ETHYL-1,3,4-THIADIAZOL-2-YL)-, SODIUM SALT (1:1)

Systematic Name

English

SULFANILAMIDE, N1-(5-ETHYL-1,3,4-THIADIAZOL-2-YL)-, MONOSODIUM SALT

Systematic Name

English

SODIUM ETAZOL

Brand Name

English

ETHAZOLE SODIUM

Common Name

English

NSC-46052

Code

English

SODIUM, (N1-(5-ETHYL-1,3,4-THIADIAZOL-2-YL)SULFANILAMIDO)-

Systematic Name

English

SULFAETHIDOLE SUDIUM SALT

Common Name

English

ETHAZOLE SODIUM SALT

Common Name

English

Code System Code Type Description

FDA UNII

389JVK194W

Created by admin on Sat Dec 16 10:00:50 GMT 2023 , Edited by admin on Sat Dec 16 10:00:50 GMT 2023

PRIMARY

NSC

46052

Created by admin on Sat Dec 16 10:00:50 GMT 2023 , Edited by admin on Sat Dec 16 10:00:50 GMT 2023

PRIMARY

PUBCHEM

12835056

Created by admin on Sat Dec 16 10:00:50 GMT 2023 , Edited by admin on Sat Dec 16 10:00:50 GMT 2023

PRIMARY

CAS

1904-95-6

Created by admin on Sat Dec 16 10:00:50 GMT 2023 , Edited by admin on Sat Dec 16 10:00:50 GMT 2023

PRIMARY

Related Record Type Details


					R77Q4O5ZMD

SULFAETHIDOLE

ACTIVE MOIETY

Details

SMILES

InChI

DescriptionSources: http://www.drugfuture.com/chemdata/sulfaethidole.html | https://www.ndrugs.com/?s=sulfamethizole/sulfaethidole | https://www.ncbi.nlm.nih.gov/pubmed/13636044

Originator

Approval Year

Conditions

Approved Use

Launch Date

Cmax

Funbound

Sourcing

PubMed

Patents

Sample Use Guides

Description
Sources: http://www.drugfuture.com/chemdata/sulfaethidole.html | https://www.ndrugs.com/?s=sulfamethizole/sulfaethidole | https://www.ncbi.nlm.nih.gov/pubmed/13636044

C_max

F_unbound