Flumoxonide, an acetal derivative, is a synthetic glucocorticoid corticosteroid, it is an antiinflammatory agent for topical use.

Quinterenol is a substituted 8-hydroxyquinoline derivative patented by Pfizer, Chas., and Co., Inc. as a bronchodilator. Quinterenol acts as a beta-adrenergic agonist that increased ventricular rate in most of the experimental animals.

AR-42, also known as (S)-HDAC-42, is a phenylbutyrate-based histone deacetylase (HDAC) inhibitor. HDACs are enzymes that determine acetylation status of histones, thereby affecting chromatin structure and regulating the expression and activity of numerous proteins involved in both cancer initiation and cancer progression. AR-42 possesses antitumor activity at multiple cellular levels. It is currently in Phase I/Ib trials for hematological malignancies and solid tumors.

Metoserpate (SU9064) is a sedative drug used in veterinary. PACITRAN (metoserpate hydrochloride) is indicated as a tranquilizer in stressed poultry.

Lortalamine is a new non-tricyclic anti-depressant compound. Lortalamine antagonizes in a dose-related manner reserpine-induced ptosis and hypothermia, and is far more potent than imipramine in this regard. The compound potentiates yohimbine toxicity in mice and, in the anesthetized dog, diminishes the tyramine pressure response while increasing the response to norepinephrine. These results would indicate the capacity for lortalamine to act as a norepinephrine uptake inhibitor, and indeed, lortalamine is more potent than imipramine in inhibiting norepinephrine uptake by rat brain cortex slices. Lortalamine does not inhibit serotonin uptake by rat midbrain slices. Lortalamine has a high affinity and high selectivity for the norepinephrine transporter. Lortalamine treated dogs showed, progressively, bilateral mydriasis, conjunctivitis, epiphora, corneal oedema and corneal erosions.

Ethynerone (MK 665) is an oral contraceptive steroid. In preclinical studies, it induced mammary tumors.

Ciprocinonide (RS-2386) is a synthetic glucocorticoid corticosteroid. It was developed in the 1980s for a topical administration as a component of the Triple Corticoid Integrated System.

Procinonide is a derivative of fluocinolone acetonide that has been applied topically with fluocinonide and ciprocinonide in the management of various skin disorders.

KETAZOCINE, a benzomorphan derivative, is a kappa opioid receptor agonist. It is used in opioid receptor research.