KETAZOCINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C18H23NO2
Molecular Weight	285.3807
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of KETAZOCINE

Structure Search

SMILES

C[C@H]1[C@@H]2N(CC3CC3)CC[C@@]1(C)C4=CC(O)=CC=C4C2=O

InChI

InChIKey=HQBZLVPZOGIAIQ-SDDDUWNISA-N

InChI=1S/C18H23NO2/c1-11-16-17(21)14-6-5-13(20)9-15(14)18(11,2)7-8-19(16)10-12-3-4-12/h5-6,9,11-12,16,20H,3-4,7-8,10H2,1-2H3/t11-,16-,18+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C18H23NO2
Molecular Weight	285.3807
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3018228 | https://www.ncbi.nlm.nih.gov/pubmed/6128693

KETAZOCINE, a benzomorphan derivative, is a kappa opioid receptor agonist. It is used in opioid receptor research.

CNS Activity

Approval Year

PubMed

PubMed

Title	Date	PubMed
Kappa-receptor selective binding of opioid ligands with a heterocyclic bicyclo[3.3.1]nonan-9-one structure.	2003	14535620

Patents

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:20:04 GMT 2023` Edited by `admin` on `Fri Dec 15 15:20:04 GMT 2023`
Record UNII	6IO4IG518S
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

KETAZOCINE

Official Name

English

(2R*,6S*,11S*)-3-(CYCLOPROPYLMETHYL)-3,4,5,6-TETRAHYDRO-8-HYDROXY-6,11-DIMETHYL-2,6-METHANO-3-BENZAZOCIN-1(2H)-ONE

Common Name

English

2,6-METHANO-3-BENZAZOCIN-1(2H)-ONE, 3-(CYCLOPROPYLMETHYL)-3,4,5,6-TETRAHYDRO-8-HYDROXY-6,11-DIMETHYL-, (2.ALPHA.,6.ALPHA.,11S*)-

Common Name

English

ketazocine [INN]

Common Name

English

WIN 34,276

Code

English

WIN-34276

Code

English

KETAZOCINE [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C67413

Created by admin on Fri Dec 15 15:20:04 GMT 2023 , Edited by admin on Fri Dec 15 15:20:04 GMT 2023

Code System Code Type Description

PUBCHEM

3054741

Created by admin on Fri Dec 15 15:20:04 GMT 2023 , Edited by admin on Fri Dec 15 15:20:04 GMT 2023

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CAS

36292-69-0

Created by admin on Fri Dec 15 15:20:04 GMT 2023 , Edited by admin on Fri Dec 15 15:20:04 GMT 2023

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WIKIPEDIA

KETAZOCINE

Created by admin on Fri Dec 15 15:20:04 GMT 2023 , Edited by admin on Fri Dec 15 15:20:04 GMT 2023

PRIMARY

INN

3876

Created by admin on Fri Dec 15 15:20:04 GMT 2023 , Edited by admin on Fri Dec 15 15:20:04 GMT 2023

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FDA UNII

6IO4IG518S

Created by admin on Fri Dec 15 15:20:04 GMT 2023 , Edited by admin on Fri Dec 15 15:20:04 GMT 2023

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EVMPD

SUB08367MIG

Created by admin on Fri Dec 15 15:20:04 GMT 2023 , Edited by admin on Fri Dec 15 15:20:04 GMT 2023

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MESH

C012395

Created by admin on Fri Dec 15 15:20:04 GMT 2023 , Edited by admin on Fri Dec 15 15:20:04 GMT 2023

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NCI_THESAURUS

C83853

Created by admin on Fri Dec 15 15:20:04 GMT 2023 , Edited by admin on Fri Dec 15 15:20:04 GMT 2023

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EPA CompTox

DTXSID10897529

Created by admin on Fri Dec 15 15:20:04 GMT 2023 , Edited by admin on Fri Dec 15 15:20:04 GMT 2023

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ChEMBL

CHEMBL2107292

Created by admin on Fri Dec 15 15:20:04 GMT 2023 , Edited by admin on Fri Dec 15 15:20:04 GMT 2023

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SMS_ID

100000082868

Created by admin on Fri Dec 15 15:20:04 GMT 2023 , Edited by admin on Fri Dec 15 15:20:04 GMT 2023

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Related Record Type Details


					2BJ58BX78W

KAPPA-TYPE OPIOID RECEPTOR

TARGET -> AGONIST

Comments:

Mouse tail test.

Qualification:

ED50

Amount:

Related Record Type Details


					6IO4IG518S

ACTIVE MOIETY

Amount: