U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 1091 - 1100 of 12523 results

Status:
Investigational
Source:
INN:lodiperone
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Lodiperon exhibited neuroleptic activity with very low liability to the extrapyramidal side effects. Its activity was greater than that of butropipazone and fluanisone, while of the same order of that of chlorpromazine; however, lodiperon showed a longer lasting activity and minor ability to produce catalepsy as compared with the reference drugs.
Status:
Investigational
Source:
INN:elfazepam
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Elfazepam is a benzodiazepine and a feed intake stimulant. Administration of elfazepam can induce animals to eat large meals. While rumen fermentation per se is not influenced by elfazepam, ruminal and abomasal motility and secretory functions are reduced.
Status:
Investigational
Source:
INN:elisartan
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)


Elisartan (HN 65021) is a selective, orally active, nonpeptide angiotensin II (AT1) antagonist. It antagonizes angiotensin receptor-mediated vasoconstriction. Elisartan was being assessed for the treatment of hypertension.
Status:
Investigational
Source:
INN:binfloxacin
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Binfloxacin is a topoisomerase inhibitor that was studied as an antibacterial agent.
Status:
Investigational
Source:
INN:fluoresone [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Fluoresone is an anticonvulsant, analgesic, anxiolytic agent. It is used in the treatment of epilepsy.
Fluprazine (previously known as DU27716), a psychoactive drug was studied as a behaviorally selective, anti-aggressive agent. Experiments on rodents have shown that fluprazine didn’t appreciably affect defensive attack or other defensive behaviors even though it strongly inhibited offensive attack. This agent is used to test both differences and similarities in neurochemical substrates and adaptive significance of different forms of intraspecific aggression.
Status:
Investigational
Source:
INN:ibrotamide [INN]
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Ibrotamide (also known as 2-Bromo-2-ethylisovaleramide) was developed as a hypnotic and sedative agent. Information about the current use of this drug is not available.
Status:
Investigational
Source:
INN:amoxecaine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

AMOXECAINE is an local anaesthetic.
Status:
Investigational
Source:
JAN:BEPERIDIUM IODIDE [JAN]
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Beperidium (also known as SX-810 ) is a competitive antagonist against acetylcholine. Experiments on animal have shown that this compound exhibited spasmolytic and antiulcerative activities without exerting systemic antimuscarinic side effects.
Rubitecan [Orathecin™] is a topoisomerase I inhibitor extracted from the bark and leaves of the Camptotheca acuminata tree, which is native to China. Rubitecan is an oral compound being developed for the treatment of pancreatic cancer and other solid tumours by SuperGen. Rubitecan binds to and inhibits the enzyme topoisomerase I and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells; this agent also prevents repair of reversible single-strand DNA breaks.

Showing 1091 - 1100 of 12523 results