BINFLOXACIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H22FN3O3
Molecular Weight	359.3947
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of BINFLOXACIN

Structure Search

SMILES

CCN1C=C(C(O)=O)C(=O)C2=CC(F)=C(C=C12)N3CCN4CCC3CC4

InChI

InChIKey=UBGCCYGMLOBJOJ-UHFFFAOYSA-N

InChI=1S/C19H22FN3O3/c1-2-22-11-14(19(25)26)18(24)13-9-15(20)17(10-16(13)22)23-8-7-21-5-3-12(23)4-6-21/h9-12H,2-8H2,1H3,(H,25,26)

HIDE SMILES / InChI

Molecular Formula	C19H22FN3O3
Molecular Weight	359.3947
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://books.google.ru/books?id=x0hZDwAAQBAJ&pg=PA360&lpg=PA360&dq=BINFLOXACIN&source=bl&ots=AdTIPMVk_L&sig=ACfU3U1LQgbCZ67JNbGP4UzaYSyT1CPMsw&hl=ru&sa=X&ved=2ahUKEwih3OLxs4ziAhXvyKYKHeeLAIY4ChDoATACegQICRAB#v=onepage&q=BINFLOXACIN&f=false

Binfloxacin is a topoisomerase inhibitor that was studied as an antibacterial agent.

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
DNA topoisomerase activity 1 Target ID: GO:0003916 Sources: https://books.google.ru/books?id=x0hZDwAAQBAJ&pg=PA360&lpg=PA360&dq=BINFLOXACIN&source=bl&ots=AdTIPMVk_L&sig=ACfU3U1LQgbCZ67JNbGP4UzaYSyT1CPMsw&hl=ru&sa=X&ved=2ahUKEwih3OLxs4ziAhXvyKYKHeeLAIY4ChDoATACegQICRAB#v=onepage&q=BINFLOXACIN&f=false	Inhibitor 8297

PubMed

PubMed

Title	Date	PubMed
Metabolism of theophylline and its inhibition by fluoroquinolones in rat hepatic microsomes.	1995 Jun	7483657

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:35:16 GMT 2023` Edited by `admin` on `Fri Dec 15 15:35:16 GMT 2023`
Record UNII	78VM28ZA2H
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BINFLOXACIN

Official Name

English

7-(1,4-Diazabicyclo[3.2.2]non-4-yl)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

Systematic Name

English

CP-73,049

Code

English

3-QUINOLINECARBOXYLIC ACID, 7-(1,4-DIAZABICYCLO(3.2.2)NON-4-YL)-1-ETHYL-6-FLUORO-1,4-DIHYDRO-4-OXO-

Common Name

English

CP-73049

Code

English

binfloxacin [INN]

Common Name

English

BINFLOXACIN [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C795

Created by admin on Fri Dec 15 15:35:16 GMT 2023 , Edited by admin on Fri Dec 15 15:35:16 GMT 2023

Code System Code Type Description

CAS

108437-28-1

Created by admin on Fri Dec 15 15:35:16 GMT 2023 , Edited by admin on Fri Dec 15 15:35:16 GMT 2023

PRIMARY

NCI_THESAURUS

C72632

Created by admin on Fri Dec 15 15:35:16 GMT 2023 , Edited by admin on Fri Dec 15 15:35:16 GMT 2023

PRIMARY

FDA UNII

78VM28ZA2H

Created by admin on Fri Dec 15 15:35:16 GMT 2023 , Edited by admin on Fri Dec 15 15:35:16 GMT 2023

PRIMARY

PUBCHEM

166565

Created by admin on Fri Dec 15 15:35:16 GMT 2023 , Edited by admin on Fri Dec 15 15:35:16 GMT 2023

PRIMARY

SMS_ID

100000085887

Created by admin on Fri Dec 15 15:35:16 GMT 2023 , Edited by admin on Fri Dec 15 15:35:16 GMT 2023

PRIMARY

INN

6313

Created by admin on Fri Dec 15 15:35:16 GMT 2023 , Edited by admin on Fri Dec 15 15:35:16 GMT 2023

PRIMARY

EVMPD

SUB05836MIG

Created by admin on Fri Dec 15 15:35:16 GMT 2023 , Edited by admin on Fri Dec 15 15:35:16 GMT 2023

PRIMARY

ChEMBL

CHEMBL346948

Created by admin on Fri Dec 15 15:35:16 GMT 2023 , Edited by admin on Fri Dec 15 15:35:16 GMT 2023

PRIMARY

USAN

Z-68

Created by admin on Fri Dec 15 15:35:16 GMT 2023 , Edited by admin on Fri Dec 15 15:35:16 GMT 2023

PRIMARY

EPA CompTox

DTXSID70148549

Created by admin on Fri Dec 15 15:35:16 GMT 2023 , Edited by admin on Fri Dec 15 15:35:16 GMT 2023

PRIMARY

Related Record Type Details


					78VM28ZA2H

ACTIVE MOIETY