Lifibrate is the antihyperlipidemic agent. It is a potent hepatic peroxisome proliferator. Administration of lifibrate at a dietary concentration of 0.15% for 3 weeks, increased the activity of catalase in both liver and kidney of male wild type (Cs-a strain) mice. The hypolipidemic activity of lifibrate is eight to nine times greater than that of chlorphenoxy isobutyric acid ethyl ester in the male Wistar rat.

Nisobamate is a tranquilizer, sedative and hypnotic.

Harmine (aka telepathine) is a fluorescent harmala alkaloid belonging to the beta-carboline family of compounds. It is a naturally occurring metabolite in a number of plants, notably the Middle Eastern plant harmal or Syrian rue (Peganum harmala) and the South American vine Banisteriopsis caapi. Harmine is a reversible inhibitor of monoamine oxidase A (MAO-A), but not MAO-B. Harmine has been found to have potential anti-cancer and neuroprotective properties, and also promotes differentiation of osteoblasts and chondrocytes while inhibiting osteoclastogenesis. Harmine has also been used as a C-11 labeled probe in positron emission tomography.

Oxotremorine, a metabolite of tremorine, is a non-hydrolyzed muscarinic acetylcholine receptor agonist used as a research tool. This compound is a muscarinic agent equal in potency to acetylcholine, but completely lacking in nicotinic activity.

Gloximonam (SQ-82531) is a beta-lactam antibiotic. This is a class of antibiotics that contains a beta-lactam ring in their molecular structure, such as penicillin derivatives. Gloximonam is orally absorbed and has shown anti-bacterial activity against different bacteria of the Enterobacteriaceae and Haemophilus influenzae families. Gloximonam is not effective against staphylococci and strict anaerobes (like aztreonam) and (unlike aztreonam) against Pseudomonas aeruginosa.

Torbafylline is a xanthine derivative. Torbafylline significantly ameliorated the decreased skeletal muscle blood flow, red cell flux and surface pO2 after acute occlusion of the femoral artery, with more pronounced effects on the microcirculatory parameters, the laser-Doppler flux and pO2. Torbafylline treatment caused an increased lactate dehydrogenase activity in intact fast muscles and decreased it in soleus. Torbafylline decreased the activity of citrate synthase but increased activity of 3-hydroxyacyl-CoA dehydrogenase in soleus. Torbafylline is a powerful inhibitor of muscle wasting that blocks enhanced Ub-proteasome-dependent proteolysis in situations where TNF production rises, including cancer and sepsis. Torbafylline suppresses malaria antigen or LPS-induced secretion of TNF-a and IL-1a secretion, but not of IL-6 from human mononuclear cells in vitro. Torbafylline also blocks TNF-a and IL-1a secretion by malaria parasite preparations indicating that it may be useful in the treatment of malaria. Torbafylline has a protective effect on antigen-induced bronchoconstriction in guinea pigs and may be a useful agent in the therapy of bronchial asthma. Torbafylline had been in phase II clinical trial for the treatment of peripheral arterial occlusive disorders. However, this development was discontinued.

Methanesulfonyl fluoride (SNX 001), a very long-acting CNS-selective acetylcholinesterase inhibitor, was studied as a palliative treatment for senile dementia of the Alzheimer type. This drug successfully completed phase I clinical trials where it showed effectively enhance memory in patients with Alzheimer's disease. However, it appears that further studies were discontinued.

Carperidine is a 4-phenylpiperidine derivative that is related to the opioid analgesic drug pethidine. Carperidine is not currently used in medicine. Presumably it has similar effects to other opioid derivatives, such as analgesia, sedation, nausea and respiratory depression, however unlike most opioid derivatives it is not specifically listed as an illegal drug, although it is on the drugs and poisons lists of some countries, and would probably be regarded as a controlled substance analogue of pethidine on the grounds of its related chemical structure in some jurisdictions such as the USA, Canada, Australia and New Zealand.